An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling

(2010) Nicholas Paquette et al.   MOLECULAR CELL

Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation

(2009) Jing Shan et al.   MOLECULAR CELL

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

(2009) Martin Schwickart et al.   NATURE

BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis

(2008) Georg Gdynia et al.   APOPTOSIS

Deubiquitylating enzymes and disease

(2008) Shweta Singhal et al.   BMC BIOCHEMISTRY

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Positive and negative signaling components involved in TNFα-induced NF-κB activation

(2008) Hongxiu Li et al.   CYTOKINE

Ubiquitin-mediated regulation of TNFR1 signaling

(2008) Ingrid E. Wertz et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Down-regulation of the De-ubiquitinating Enzyme Ubiquitin-specific Protease 2 Contributes to Tumor Necrosis Factor-α-induced Hepatocyte Survival

(2008) Florian Haimerl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

(2008) Véronique Baud et al.   NATURE REVIEWS DRUG DISCOVERY

TNFα blockade in human diseases: Mechanisms and future directions

(2007) Maida Wong et al.   CLINICAL IMMUNOLOGY