Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells

Gab2 Phosphorylation by RSK Inhibits Shp2 Recruitment and Cell Motility

(2013) X. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34-positive compartment

(2012) Alfonso Quintás-Cardama et al.   CANCER

Imatinib-dependent tyrosine phosphorylation profiling of Bcr-Abl-positive chronic myeloid leukemia cells

(2012) C Preisinger et al.   LEUKEMIA

Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII

(2012) Wojciech Jankowski et al.   Nature Chemical Biology

The Degradative Inventory of the Cell: Proteomic Insights

(2011) Rudolf Engelke et al.   ANTIOXIDANTS & REDOX SIGNALING

The immunohistochemical staining pattern of Gab2 correlates with distinct stages of chronic myeloid leukemia

(2011) Konrad Aumann et al.   HUMAN PATHOLOGY

Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferation

(2011) Sanjeev K. Baniwal et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Order and disorder in large multi-site docking proteins of the Gab family—implications for signalling complex formation and inhibitor design strategies

(2011) Philip C. Simister et al.   Molecular BioSystems

System-Wide Temporal Characterization of the Proteome and Phosphoproteome of Human Embryonic Stem Cell Differentiation

(2011) K. T. G. Rigbolt et al.   Science Signaling

Self-Organization and Regulation of Intrinsically Disordered Proteins with Folded N-Termini

(2011) Philip C. Simister et al.   PLOS BIOLOGY

Quantitative proteomics for the analysis of spatio-temporal protein dynamics during autophagy

(2010) Andrea C. Zimmermann et al.   Autophagy

Docking proteins

(2010) Tilman Brummer et al.   FEBS Journal

Molecular and clinical analysis ofRAF1in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation

(2010) Tomoko Kobayashi et al.   HUMAN MUTATION

Chronic myeloid leukemia: mechanisms of blastic transformation

(2010) Danilo Perrotti et al.   JOURNAL OF CLINICAL INVESTIGATION

Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation

(2010) Maria Teresa Herrera Abreu et al.   MOLECULAR BIOLOGY OF THE CELL

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization

(2010) B Titz et al.   ONCOGENE

Crk and CrkL adaptor proteins: networks for physiological and pathological signaling

(2009) Raymond B Birge et al.   Cell Communication and Signaling

Altered Distribution of Aquaporin 5 and its C-Terminal Binding Protein in the Lacrimal Glands of a Mouse Model for Sjögren's Syndrome

(2009) Yoshiki Ohashi et al.   CURRENT EYE RESEARCH

SLP-65 Phosphorylation Dynamics Reveals a Functional Basis for Signal Integration by Receptor-proximal Adaptor Proteins

(2009) Thomas Oellerich et al.   MOLECULAR & CELLULAR PROTEOMICS

Charting the molecular network of the drug target Bcr-Abl

(2009) M. Brehme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the SH3C Domain of Grb2

(2009) Maria Harkiolaki et al.   STRUCTURE

How to Grb2 a Gab

(2009) Franziska U. Wöhrle et al.   STRUCTURE

Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells

(2008) J. Wu et al.   BLOOD

Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein

(2008) Tilman Brummer et al.   EMBO JOURNAL

A new mechanism for the regulation of Gab1 recruitment to the plasma membrane

(2008) R. Eulenfeld et al.   JOURNAL OF CELL SCIENCE

Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib

(2008) Oliver Hantschel et al.   LEUKEMIA & LYMPHOMA

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY