Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII

Identification of CrkL-SH3 Binding Proteins from Embryonic Murine Brain: Implications for Reelin Signaling during Brain Development

(2011) Mujeeburahim Cheerathodi et al.   JOURNAL OF PROTEOME RESEARCH

Crk and CrkL present with different expression and significance in epithelial ovarian carcinoma

(2011) Jin Wang et al.   MOLECULAR CARCINOGENESIS

Tuning protein autoinhibition by domain destabilization

(2011) Jae-Hyun Cho et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation

(2011) G Sriram et al.   ONCOGENE

BCR-ABL1 tyrosine kinase activity at diagnosis, as determined via the pCrkL/CrkL ratio, is predictive of clinical outcome in chronic myeloid leukaemia

(2010) Claire M. Lucas et al.   BRITISH JOURNAL OF HAEMATOLOGY

miR-126 functions as a tumour suppressor in human gastric cancer

(2010) Runhua Feng et al.   CANCER LETTERS

A Specific Need for CRKL in p210BCR-ABL-Induced Transformation of Mouse Hematopoietic Progenitors

(2010) J.-H. Seo et al.   CANCER RESEARCH

Downstream of Tyrosine Kinase 1 and 2 Play Opposing Roles in CD200 Receptor Signaling

(2010) R. Mihrshahi et al.   JOURNAL OF IMMUNOLOGY

Structural basis for regulation of the Crk signaling protein by a proline switch

(2010) Paramita Sarkar et al.   Nature Chemical Biology

ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity

(2010) J. Colicelli   Science Signaling

The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3

(2010) Hui Wang et al.   TUMOR BIOLOGY

Crk and CrkL adaptor proteins: networks for physiological and pathological signaling

(2009) Raymond B Birge et al.   Cell Communication and Signaling

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

(2009) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals

(2009) S. Antoku et al.   JOURNAL OF CELL SCIENCE

Proline Isomerization Preorganizes the Itk SH2 Domain for Binding to the Itk SH3 Domain

(2009) Andrew Severin et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural and Functional Basis of a Role for CRKL in a Fibroblast Growth Factor 8-Induced Feed-Forward Loop

(2009) J.-H. Seo et al.   MOLECULAR AND CELLULAR BIOLOGY

Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer

(2009) Y H Kim et al.   ONCOGENE

An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment

(2009) P. J. Mintz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Observing biological dynamics at atomic resolution using NMR

(2009) Anthony K. Mittermaier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Induction of cell retraction by the combined actions of Abl–CrkII and Rho–ROCK1 signaling

(2008) XiaoDong Huang et al.   JOURNAL OF CELL BIOLOGY

Highly parallel identification of essential genes in cancer cells

(2008) B. Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new twist to adaptor proteins contributes to regulation of lymphocyte cell signaling

(2008) Noah Isakov   TRENDS IN IMMUNOLOGY