Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression

Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ

(2012) R. Godfrey et al.   BLOOD

Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype

(2011) Victor Chun Lam Wong et al.   INTERNATIONAL JOURNAL OF CANCER

Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 Signaling

(2011) Deepika Arora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications

(2011) Guido Marcucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas

(2011) S Messina et al.   ONCOGENE

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

(2011) Jianbiao Zhou et al.   PLoS One

Pim2 cooperates with PML-RAR  to induce acute myeloid leukemia in a bone marrow transplantation model

(2010) S. Agrawal-Singh et al.   BLOOD

Differential Up-regulation of MAP Kinase Phosphatases MKP3/DUSP6 and DUSP5 by Ets2 and c-Jun Converge in the Control of the Growth ArrestVersusProliferation Response of MCF-7 Breast Cancer Cells to Phorbol Ester

(2010) Caroline E. Nunes-Xavier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Comprehensive Expression Profiles of Genes for Protein Tyrosine Phosphatases in Immune Cells

(2010) Y. Arimura et al.   Science Signaling

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality

(2009) D. Schmidt-Arras et al.   BLOOD

Protein tyrosine phosphatase epsilon and Neu-induced mammary tumorigenesis

(2008) Dalia Berman-Golan et al.   CANCER AND METASTASIS REVIEWS

Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease

(2008) Rafael Pulido et al.   FEBS Journal

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

Role of SHP2 for FLT3-dependent proliferation and transformation in 32D cells

(2008) J P Müller et al.   LEUKEMIA

A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis

(2008) Kristoffer Weber et al.   MOLECULAR THERAPY