Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ
Authors
Keywords
-
Journal
BLOOD
Volume 119, Issue 19, Pages 4499-4511
Publisher
American Society of Hematology
Online
2012-03-23
DOI
10.1182/blood-2011-02-336446
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”
- (2011) Robert Karisch et al. CELL
- Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases
- (2011) Åsa Sandin et al. CELLULAR SIGNALLING
- Protein-tyrosine Phosphatase DEP-1 Controls Receptor Tyrosine Kinase FLT3 Signaling
- (2011) Deepika Arora et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML
- (2011) H J M de Jonge et al. LEUKEMIA
- Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling
- (2010) Hyun Ae Woo et al. CELL
- NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
- (2010) M M Reddy et al. LEUKEMIA
- Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia
- (2010) Maria Kleppe et al. NATURE GENETICS
- 12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases
- (2010) M. Conrad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comprehensive Expression Profiles of Genes for Protein Tyrosine Phosphatases in Immune Cells
- (2010) Y. Arimura et al. Science Signaling
- Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities
- (2009) Georg T. Wondrak ANTIOXIDANTS & REDOX SIGNALING
- Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome
- (2009) S. Kayser et al. BLOOD
- Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
- (2009) H. Dohner et al. BLOOD
- BCR-ABL promotes the frequency of mutagenic single-strand annealing DNA repair
- (2009) M. S. Fernandes et al. BLOOD
- Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality
- (2009) D. Schmidt-Arras et al. BLOOD
- Structural and Functional Alterations of FLT3 in Acute Myeloid Leukemia
- (2009) S. Meshinchi et al. CLINICAL CANCER RESEARCH
- The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers
- (2009) S. Veeriah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor
- (2008) F. Breitenbuecher et al. BLOOD
- Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML
- (2008) A. Sallmyr et al. BLOOD
- Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma
- (2008) D. A. Solomon et al. CANCER RESEARCH
- Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5
- (2008) Judith Müller et al. CHEMBIOCHEM
- Protein tyrosine phosphatases: regulatory mechanisms
- (2008) Jeroen den Hertog et al. FEBS Journal
- Regulation of ROS signal transduction by NADPH oxidase 4 localization
- (2008) Kai Chen et al. JOURNAL OF CELL BIOLOGY
- Role of SHP2 for FLT3-dependent proliferation and transformation in 32D cells
- (2008) J P Müller et al. LEUKEMIA
- Reconciling the chemistry and biology of reactive oxygen species
- (2008) Christine C Winterbourn Nature Chemical Biology
- The structure of the 5′-end of the protein-tyrosine phosphatase PTPRJ mRNA reveals a novel mechanism for translation attenuation
- (2008) Luchezar Karagyozov et al. NUCLEIC ACIDS RESEARCH
- A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells
- (2008) B. Boivin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling
- (2008) J. C. Juarez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NOX enzymes as novel targets for drug development
- (2008) J. David Lambeth et al. Seminars in Immunopathology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started