150thAnniversary Series: Desmosomes and Autoimmune Disease, Perspective of Dynamic Desmosome Remodeling and Its Impairments in Pemphigus

Desmosomal Cadherins and Signaling: Lessons from Autoimmune Disease

(2014) Volker Spindler et al.   CELL COMMUNICATION AND ADHESION

150th anniversary series: Desmosomes in physiology and disease

(2014) Nicola Cirillo   CELL COMMUNICATION AND ADHESION

Pemphigus Vulgaris IgG Directly Inhibit Desmoglein 3-Mediated Transinteraction

(2014) W.-M. Heupel et al.   JOURNAL OF IMMUNOLOGY

Pemphigus herpetiformis: From first description until now

(2014) Michael Kasperkiewicz et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Pemphigus vulgaris autoimmune globulin induces Src-dependent tyrosine-phosphorylation of plakophilin 3 and its detachment from desmoglein 3

(2013) Nicola Cirillo et al.   AUTOIMMUNITY

Desmosomal adhesion and pemphigus vulgaris: the first half of the story

(2013) Nicola Cirillo et al.   CELL COMMUNICATION AND ADHESION

Structural and Functional Diversity of Desmosomes

(2013) Robert M. Harmon et al.   CELL COMMUNICATION AND ADHESION

A Pathophysiologic Role for Epidermal Growth Factor Receptor in Pemphigus Acantholysis

(2013) Meryem Bektas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MAPKAP Kinase 2 (MK2)-Dependent and -Independent Models of Blister Formation in Pemphigus Vulgaris

(2013) Xuming Mao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A New Light on an Old Disease: Adhesion Signaling in Pemphigus Vulgaris

(2013) Arnaud Galichet et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Desmosome assembly and dynamics

(2013) Oxana Nekrasova et al.   TRENDS IN CELL BIOLOGY

Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris

(2012) María P. Gil et al.   EXPERIMENTAL DERMATOLOGY

Direct evidence that PKCα positively regulates wound re-epithelialization: correlation with changes in desmosomal adhesiveness

(2012) Helen A Thomason et al.   JOURNAL OF PATHOLOGY

New insights into desmosome regulation and pemphigus blistering as a desmosome-remodeling disease

(2012) Yasuo Kitajima   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

The Extent of Desmoglein 3 Depletion in Pemphigus Vulgaris Is Dependent on Ca2+-Induced Differentiation

(2011) Volker Spindler et al.   AMERICAN JOURNAL OF PATHOLOGY

Pemphigus autoimmunity: Hypotheses and realities

(2011) Sergei A. Grando   AUTOIMMUNITY

IgG-induced clustering of desmogleins 1 and 3 in skin of patients with pemphigus fits with the desmoglein nonassembly depletion hypothesis

(2011) D.A.M. Oktarina et al.   BRITISH JOURNAL OF DERMATOLOGY

Desmoglein as a Target in Skin Disease and Beyond

(2011) Masayuki Amagai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

An Adult Passive Transfer Mouse Model to Study Desmoglein 3 Signaling in Pemphigus Vulgaris

(2011) Katja Schulze et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Binding of pemphigus vulgaris IgG to antigens in desmosome core domains excludes immune complexes rather than directly splitting desmosomes

(2010) Y. Aoyama et al.   BRITISH JOURNAL OF DERMATOLOGY

E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly

(2010) Prajakta Gosavi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling

(2010) Ryan P. Hobbs et al.   FASEB JOURNAL

Membrane-impermeable Cross-linking Provides Evidence for Homophilic, Isoform-specific Binding of Desmosomal Cadherins in Epithelial Cells

(2010) Zhuxiang Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p38MAPK Signaling and Desmoglein-3 Internalization Are Linked Events in Pemphigus Acantholysis

(2010) Puneet S. Jolly et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homologous regions of autoantibody heavy chain complementarity-determining region 3 (H-CDR3) in patients with pemphigus cause pathogenicity

(2010) Jun Yamagami et al.   JOURNAL OF CLINICAL INVESTIGATION

Desmosome Disassembly in Response to Pemphigus Vulgaris IgG Occurs in Distinct Phases and Can Be Reversed by Expression of Exogenous Dsg3

(2010) Jean M. Jennings et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell–cell detachment and processing of adhesion molecules via mechanisms that involve PKC

(2009) Nicola Cirillo et al.   EXPERIMENTAL CELL RESEARCH

Low to high Ca2+-switch causes phosphorylation and association of desmocollin 3 with plakoglobin and desmoglein 3 in cultured keratinocytes

(2009) Yumi Aoyama et al.   EXPERIMENTAL DERMATOLOGY

An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris

(2009) Maider Pretel et al.   EXPERIMENTAL DERMATOLOGY

Desmocollin 3-mediated Binding Is Crucial for Keratinocyte Cohesion and Is Impaired in Pemphigus

(2009) Volker Spindler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of the Desmosomal Protein Perp Enhances the Phenotypic Effects of Pemphigus Vulgaris Autoantibodies

(2009) Bichchau Nguyen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Classical Cadherins Regulate Desmosome Formation

(2009) Christian Michels et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hyper-adhesion: a new concept in cell–cell adhesion

(2008) David Garrod et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Pemphigus Vulgaris IgG-induced Desmoglein-3 Endocytosis and Desmosomal Disassembly Are Mediated by a Clathrin- and Dynamin-independent Mechanism

(2008) Emmanuella Delva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of Key Role of Cdk2 Overexpression in Pemphigus Vulgaris

(2008) Alessandro Lanza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of Desmosome Assembly by Monovalent Human Pemphigus Vulgaris Monoclonal Antibodies

(2008) Xuming Mao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY