Structural and Functional Diversity of Desmosomes

Keratins control intercellular adhesion involving PKC-α–mediated desmoplakin phosphorylation

(2013) Cornelia Kröger et al.   JOURNAL OF CELL BIOLOGY

Plakoglobin interacts with the transcription factor p53 and regulates the expression of 14-3-3 

(2013) Z. Aktary et al.   JOURNAL OF CELL SCIENCE

Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation

(2013) Robert M. Harmon et al.   JOURNAL OF CLINICAL INVESTIGATION

DSG3 Facilitates Cancer Cell Growth and Invasion through the DSG3-Plakoglobin-TCF/LEF-Myc/Cyclin D1/MMP Signaling Pathway

(2013) Yin-Ju Chen et al.   PLoS One

Desmosomal cadherins in zebrafish epiboly and gastrulation

(2012) Alexander Goonesinghe et al.   BMC DEVELOPMENTAL BIOLOGY

The p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancer

(2012) Tiantian Cui et al.   CARCINOGENESIS

Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency

(2012) Marina Cerrone et al.   CARDIOVASCULAR RESEARCH

Desmosomal adhesiveness is developmentally regulated in the mouse embryo and modulated during trophectoderm migration

(2012) Tomomi E. Kimura et al.   DEVELOPMENTAL BIOLOGY

The C-terminal unique region of desmoglein 2 inhibits its internalization via tail–tail interactions

(2012) Jing Chen et al.   JOURNAL OF CELL BIOLOGY

Signaling Dependent and Independent Mechanisms in Pemphigus Vulgaris Blister Formation

(2012) Masataka Saito et al.   PLoS One

Ideal, catch, and slip bonds in cadherin adhesion

(2012) S. Rakshit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The  -Catenin Destruction Complex

(2012) J. L. Stamos et al.   Cold Spring Harbor Perspectives in Biology

SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells

(2011) Yu-Heng Lai et al.   BMC CELL BIOLOGY

Molecular changes in the heart of a severe case of arrhythmogenic right ventricular cardiomyopathy caused by a desmoglein-2 null allele

(2011) Katja Gehmlich et al.   CARDIOVASCULAR PATHOLOGY

Plakophilin-2 and the migration, differentiation and transformation of cells derived from the epicardium of neonatal rat hearts

(2011) Stephanie A. Matthes et al.   CELL COMMUNICATION AND ADHESION

Desmosome dynamics in migrating epithelial cells requires the actin cytoskeleton

(2011) Brett J. Roberts et al.   EXPERIMENTAL CELL RESEARCH

Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity

(2011) Manuela Pigors et al.   HUMAN MOLECULAR GENETICS

Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis

(2011) Kaelyn D. Sumigray et al.   JOURNAL OF CELL BIOLOGY

Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes

(2011) Oxana E. Nekrasova et al.   JOURNAL OF CELL BIOLOGY

The Calcium-Sensing Receptor-Dependent Regulation of Cell–Cell Adhesion and Keratinocyte Differentiation Requires Rho and Filamin A

(2011) Chia-Ling Tu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling

(2011) Keli Kolegraff et al.   MOLECULAR BIOLOGY OF THE CELL

The three-dimensional molecular structure of the desmosomal plaque

(2011) A. Al-Amoudi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Extracellular Architecture of Adherens Junctions Revealed by Crystal Structures of Type I Cadherins

(2011) Oliver J. Harrison et al.   STRUCTURE

The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling

(2010) Ryan P. Hobbs et al.   FASEB JOURNAL

Membrane-impermeable Cross-linking Provides Evidence for Homophilic, Isoform-specific Binding of Desmosomal Cadherins in Epithelial Cells

(2010) Zhuxiang Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plakophilin 1 stimulates translation by promoting eIF4A1 activity

(2010) Annika Wolf et al.   JOURNAL OF CELL BIOLOGY

Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling

(2010) V. Todorovic et al.   JOURNAL OF CELL SCIENCE

Plakophilin-1 Localizes to the Nucleus and Interacts with Single-Stranded DNA

(2010) Tammy Sobolik-Delmaire et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Desmosome Disassembly in Response to Pemphigus Vulgaris IgG Occurs in Distinct Phases and Can Be Reversed by Expression of Exogenous Dsg3

(2010) Jean M. Jennings et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Plakophilin 2 Couples Actomyosin Remodeling to Desmosomal Plaque Assembly via RhoA

(2010) Lisa M. Godsel et al.   MOLECULAR BIOLOGY OF THE CELL

Arrhythmogenic right ventricular cardiomyopathy/dysplasia: a not so rare “disease of the desmosome” with multiple clinical presentations

(2009) Thomas Herren et al.   Clinical Research in Cardiology

Low to high Ca2+-switch causes phosphorylation and association of desmocollin 3 with plakoglobin and desmoglein 3 in cultured keratinocytes

(2009) Yumi Aoyama et al.   EXPERIMENTAL DERMATOLOGY

Interactions of Plakoglobin and β-Catenin with Desmosomal Cadherins

(2009) Hee-Jung Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Desmoglein 1–dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis

(2009) Spiro Getsios et al.   JOURNAL OF CELL BIOLOGY

Classical Cadherins Regulate Desmosome Formation

(2009) Christian Michels et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Desmosome

(2009) E. Delva et al.   Cold Spring Harbor Perspectives in Biology

Tensile Properties of Single Desmin Intermediate Filaments

(2008) Laurent Kreplak et al.   BIOPHYSICAL JOURNAL

The desmosome and pemphigus

(2008) Jens Waschke   HISTOCHEMISTRY AND CELL BIOLOGY

Plakophilin3 downregulation leads to a decrease in cell adhesion and promotes metastasis

(2008) Samrat T. Kundu et al.   INTERNATIONAL JOURNAL OF CANCER

Plakophilin 2: a critical scaffold for PKCα that regulates intercellular junction assembly

(2008) Amanda E. Bass-Zubek et al.   JOURNAL OF CELL BIOLOGY

Sequence and Structural Determinants of Strand Swapping in Cadherin Domains: Do All Cadherins Bind Through the Same Adhesive Interface?

(2008) Shoshana Posy et al.   JOURNAL OF MOLECULAR BIOLOGY

The Desmoglein-Specific Cytoplasmic Region Is Intrinsically Disordered in Solution and Interacts with Multiple Desmosomal Protein Partners

(2008) Keiichiro Kami et al.   JOURNAL OF MOLECULAR BIOLOGY

Desmosome structure, composition and function

(2007) David Garrod et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES