Desmin in muscle and associated diseases: beyond the structural function

αB-Crystallin R120G variant causes cardiac arrhythmias and alterations in the expression of Ca2+-handling proteins and endoplasmic reticulum stress in mice

(2014) Qibin Jiao et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dystrophin complex functions as a scaffold for signalling proteins

(2013) Bruno Constantin   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mechanical Players—The Role of Intermediate Filaments in Cell Mechanics and Organization

(2013) Markus J. Buehler   BIOPHYSICAL JOURNAL

Rho-associated coiled-coil kinase (ROCK) signaling and disease

(2013) Alice V. Schofield et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Networking galore: intermediate filaments and cell migration

(2013) Byung-Min Chung et al.   CURRENT OPINION IN CELL BIOLOGY

Μyospryn: a multifunctional desmin-associated protein

(2013) Elsa Tsoupri et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Posttranslational modifications of desmin and their implication in biological processes and pathologies

(2013) Daniel L. Winter et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Plectin–intermediate filament partnership in skin, skeletal muscle, and peripheral nerve

(2013) Maria J. Castañón et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo

(2013) L. Amoasii et al.   JOURNAL OF CELL SCIENCE

Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation

(2013) A. C. Humphries et al.   JOURNAL OF CELL SCIENCE

Knockdown of desmin in zebrafish larvae affects interfilament spacing and mechanical properties of skeletal muscle

(2013) Mei Li et al.   JOURNAL OF GENERAL PHYSIOLOGY

Receptor Tyrosine Kinase Ubiquitylation Involves the Dynamic Regulation of Cbl-Spry2 by Intersectin 1 and the Shp2 Tyrosine Phosphatase

(2013) M. N. Okur et al.   MOLECULAR AND CELLULAR BIOLOGY

Viral-mediated expression of desmin mutants to create mouse models of myofibrillar myopathy

(2013) Pierre Joanne et al.   Skeletal Muscle

The many faces of plectin and plectinopathies: pathology and mechanisms

(2012) Lilli Winter et al.   ACTA NEUROPATHOLOGICA

Desminopathies: pathology and mechanisms

(2012) Christoph S. Clemen et al.   ACTA NEUROPATHOLOGICA

Skeletal muscle fibrosis develops in response to desmin deletion

(2012) Gretchen A. Meyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Vimentin and the K-Ras-induced actin-binding protein control inositol-(1,4,5)-trisphosphate receptor redistribution during MDCK cell differentiation

(2012) Florent Dingli et al.   JOURNAL OF CELL SCIENCE

Intersectin (ITSN) Family of Scaffolds Function as Molecular Hubs in Protein Interaction Networks

(2012) Katy A. Wong et al.   PLoS One

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

Physiology, structure, and susceptibility to injury of skeletal muscle in mice lacking keratin 19-based and desmin-based intermediate filaments

(2011) Richard M. Lovering et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

S100A1 and calmodulin regulation of ryanodine receptor in striated muscle

(2011) Benjamin L. Prosser et al.   CELL CALCIUM

Autophagy and p62 in Cardiac Proteinopathy

(2011) Qingwen Zheng et al.   CIRCULATION RESEARCH

Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration

(2011) Ondra M. Kielbasa et al.   FASEB JOURNAL

Loss of desmin triggers mechanosensitivity and up-regulation of Ankrd1 expression through Akt-NF-κB signaling pathway in smooth muscle cells

(2011) Junaith S. Mohamed et al.   FASEB JOURNAL

Identification and characterization of splicing variants of PLEKHA5 (Plekha5) during brain development

(2011) Kenichiro Yamada et al.   GENE

Characterization of the failing murine heart in a desmin knock-out model using a clinical 3 T MRI scanner

(2011) A. M. Sprinkart et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

Cytoskeleton in motion: the dynamics of keratin intermediate filaments in epithelia

(2011) Reinhard Windoffer et al.   JOURNAL OF CELL BIOLOGY

Inroads into the structure and function of intermediate filament networks

(2011) Robert D. Goldman et al.   JOURNAL OF STRUCTURAL BIOLOGY

Desmin-related myopathy

(2010) KY van Spaendonck-Zwarts et al.   CLINICAL GENETICS

Intersectin multidomain adaptor proteins: Regulation of functional diversity

(2010) Liudmyla Tsyba et al.   GENE

S100A1: A Regulator of Striated Muscle Sarcoplasmic Reticulum Ca2+Handling, Sarcomeric, and Mitochondrial Function

(2010) Mirko Völkers et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle

(2010) Karim Hnia et al.   JOURNAL OF CLINICAL INVESTIGATION

A human MAP kinase interactome

(2010) Sourav Bandyopadhyay et al.   NATURE METHODS

Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1

(2010) Angela Brieger et al.   PROTEOMICS

In-vivo characterization of human dilated cardiomyopathy genes in zebrafish

(2009) Britta Vogel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The dynamic properties of intermediate filaments during organelle transport

(2009) L. Chang et al.   JOURNAL OF CELL SCIENCE

Introducing intermediate filaments: from discovery to disease

(2009) John E. Eriksson et al.   JOURNAL OF CLINICAL INVESTIGATION

Intermediate filaments: primary determinants of cell architecture and plasticity

(2009) Harald Herrmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Tragedy in a heartbeat: malfunctioning desmin causes skeletal and cardiac muscle disease

(2009) Lev G. Goldfarb et al.   JOURNAL OF CLINICAL INVESTIGATION

Desmin and Vimentin Intermediate Filament Networks: Their Viscoelastic Properties Investigated by Mechanical Rheometry

(2009) Michael Schopferer et al.   JOURNAL OF MOLECULAR BIOLOGY

Severe infantile-onset cardiomyopathy associated with a homozygous deletion in desmin

(2009) Gerard Piñol-Ripoll et al.   NEUROMUSCULAR DISORDERS

T-tubule disorganization and defective excitation-contraction coupling in muscle fibers lacking myotubularin lipid phosphatase

(2009) L. Al-Qusairi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Myotubularin Function Results in T-Tubule Disorganization in Zebrafish and Human Myotubular Myopathy

(2009) James J. Dowling et al.   PLoS Genetics

Switch in Fas-activated death signaling pathway as result of keratin 8/18-intermediate filament loss

(2008) Stéphane Gilbert et al.   APOPTOSIS

Human α-synemin interacts directly with vinculin and metavinculin

(2008) Ning Sun et al.   BIOCHEMICAL JOURNAL

Syncoilin, an intermediate filament-like protein linked to the dystrophin associated protein complex in skeletal muscle

(2008) C. Moorwood   CELLULAR AND MOLECULAR LIFE SCIENCES

A missense mutation in desmin tail domain linked to human dilated cardiomyopathy promotes cleavage of the head domain and abolishes its Z-disc localization

(2008) Manolis Mavroidis et al.   FASEB JOURNAL

Deregulated Protein Kinase A Signaling and Myospryn Expression in Muscular Dystrophy

(2008) Joseph G. Reynolds et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms

(2008) Patryk Konieczny et al.   JOURNAL OF CELL BIOLOGY

Mice expressing L345P mutant desmin exhibit morphological and functional changes of skeletal and cardiac mitochondria

(2008) Anna Kostareva et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Distinct muscle imaging patterns in myofibrillar myopathies

(2008) D. Fischer et al.   NEUROLOGY

Electron microscopy in myofibrillar myopathies reveals clues to the mutated gene

(2008) K.G. Claeys et al.   NEUROMUSCULAR DISORDERS

Cell adhesion in zebrafish myogenesis: Distribution of intermediate filaments, microfilaments, intracellular adhesion structures and extracellular matrix

(2008) Manoel L. Costa et al.   CELL MOTILITY AND THE CYTOSKELETON

GeneMANIA: a real-time multiple association network integration algorithm for predicting gene function

(2008) Sara Mostafavi et al.   GENOME BIOLOGY