Histone variants: key players of chromatin

Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma

(2014) H. Li et al.   BLOOD

CENP-A octamers do not confer a reduction in nucleosome height by AFM

(2014) Christine A Codomo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CENP-A octamers do not confer a reduction in nucleosome height by AFM

(2014) Marcin P Walkiewicz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Octameric CENP-A Nucleosomes Are Present at Human Centromeres throughout the Cell Cycle

(2013) Abbas Padeganeh et al.   CURRENT BIOLOGY

Histone variants in pluripotency and disease

(2013) P. J. Skene et al.   DEVELOPMENT

The Embryonic Linker Histone H1 Variant of Drosophila, dBigH1, Regulates Zygotic Genome Activation

(2013) Salvador Pérez-Montero et al.   DEVELOPMENTAL CELL

SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal

(2013) Olivier Binda et al.   Epigenetics

H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin

(2013) P. Chen et al.   GENES & DEVELOPMENT

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

(2013) K.-M. Chan et al.   GENES & DEVELOPMENT

Histone Variants in Development and Diseases

(2013) Ping Chen et al.   Journal of Genetics and Genomics

CENP-A confers a reduction in height on octameric nucleosomes

(2013) Matthew D D Miell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The octamer is the major form of CENP-A nucleosomes at human centromeres

(2013) Dan Hasson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

H1 histones: current perspectives and challenges

(2013) S. W. Harshman et al.   NUCLEIC ACIDS RESEARCH

Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma

(2013) Francesca Rappa et al.   PLoS One

Phosphorylation of the CENP-A amino-terminus in mitotic centromeric chromatin is required for kinetochore function

(2013) D. Goutte-Gattat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Posttranslational modification of CENP-A influences the conformation of centromeric chromatin

(2013) A. O. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

(2013) P. W. Lewis et al.   SCIENCE

Prognostic value of centromere protein-A expression in patients with epithelial ovarian cancer

(2013) Jun-Jun Qiu et al.   TUMOR BIOLOGY

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency

(2013) Alexandre Gaspar-Maia et al.   Nature Communications

The Genomic Landscape of the Somatic Linker Histone Subtypes H1.1 to H1.5 in Human Cells

(2013) Annalisa Izzo et al.   Cell Reports

Foxa2 and H2A.Z Mediate Nucleosome Depletion during Embryonic Stem Cell Differentiation

(2012) Zhaoyu Li et al.   CELL

Oocyte-specific linker histone H1foo is an epigenomic modulator that decondenses chromatin and impairs pluripotency

(2012) Koji Hayakawa et al.   Epigenetics

ATRX-mediated chromatin association of histone variant macroH2A1 regulates  -globin expression

(2012) K. Ratnakumar et al.   GENES & DEVELOPMENT

A dual role of linker histone H1.4 Lys 34 acetylation in transcriptional activation

(2012) K. Kamieniarz et al.   GENES & DEVELOPMENT

MacroH2A1 Regulates the Balance between Self-Renewal and Differentiation Commitment in Embryonic and Adult Stem Cells

(2012) C. Creppe et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2A.Z Controls a Critical Chromatin Remodeling Step Required for DNA Double-Strand Break Repair

(2012) Ye Xu et al.   MOLECULAR CELL

DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition

(2012) Simon J. Elsässer et al.   NATURE

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics

(2012) Maxim Nekrasov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1

(2012) N. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research

(2011) Alesia Ivashkevich et al.   CANCER LETTERS

Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity

(2011) Manolis Papamichos-Chronakis et al.   CELL

Histone variant macroH2A confers resistance to nuclear reprogramming

(2011) Vincent Pasque et al.   EMBO JOURNAL

Histone H1 Variants Are Differentially Expressed and Incorporated into Chromatin during Differentiation and Reprogramming to Pluripotency

(2011) Jean-Michel Terme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Linker Region of MacroH2A Promotes Self-association of Nucleosomal Arrays

(2011) Uma M. Muthurajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H1 expression in human prostate cancer tissues and cell lines

(2011) Shinya Sato et al.   PATHOLOGY INTERNATIONAL

Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse

(2011) Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

Stepwise Histone Replacement by SWR1 Requires Dual Activation with Histone H2A.Z and Canonical Nucleosome

(2010) Ed Luk et al.   CELL

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

Phosphorylation of Histone H2A.X by DNA-dependent Protein Kinase Is Not Affected by Core Histone Acetylation, but It Alters Nucleosome Stability and Histone H1 Binding

(2010) Andra Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetrameric organization of vertebrate centromeric nucleosomes

(2010) E. K. Dimitriadis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2A.Z and H3.3 Histone Variants Affect Nucleosome Structure: Biochemical and Biophysical Studies

(2009) Amit Thakar et al.   BIOCHEMISTRY

Histone acetylation: truth of consequences?This paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Jennifer K. Choi et al.   Biochemistry and Cell Biology

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres

(2009) Elaine M. Dunleavy et al.   CELL

Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP

(2009) Daniel R. Foltz et al.   CELL

Expression of human oocyte-specific linker histone protein and its incorporation into sperm chromatin during fertilization

(2009) Yuri Mizusawa et al.   FERTILITY AND STERILITY

Sensing NAD metabolites through macro domains

(2009) Susanne Till   Frontiers in Bioscience-Landmark

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

(2009) M. J. Gamble et al.   GENES & DEVELOPMENT

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

(2009) Peter J. Cook et al.   NATURE

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

The histone variant macroH2A is an epigenetic regulator of key developmental genes

(2009) Marcus Buschbeck et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone macroH2A isoforms predict the risk of lung cancer recurrence

(2009) J C Sporn et al.   ONCOGENE

The histone H1 family: specific members, specific functions?

(2008) Annalisa Izzo et al.   BIOLOGICAL CHEMISTRY

H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment

(2008) Menno P. Creyghton et al.   CELL

FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16

(2008) Kyu Heo et al.   MOLECULAR CELL

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

(2008) Andrew Xiao et al.   NATURE

Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks

(2008) Daniel Zilberman et al.   NATURE

Depletion of Human Histone H1 Variants Uncovers Specific Roles in Gene Expression and Cell Growth

(2008) Mónica Sancho et al.   PLoS Genetics