Neuroglia in ageing and disease

Microglial Senescence

(2013) Wolfgang Streit et al.   CNS & Neurological Disorders-Drug Targets

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

(2013) Grazyna Rajkowska et al.   CURRENT DRUG TARGETS

Enhanced Asynchronous Ca2+Oscillations Associated with Impaired Glutamate Transport in Cortical Astrocytes ExpressingFmr1Gene Premutation Expansion

(2013) Zhengyu Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex and region-specific changes in astroglial markers in the aging brain

(2013) José J. Rodríguez et al.   NEUROBIOLOGY OF AGING

Enhanced Ca2+-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model

(2013) William Lee et al.   NEUROBIOLOGY OF DISEASE

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease

(2013) J.J. Rodríguez et al.   NEUROSCIENCE LETTERS

Astrogliopathology

(2013) Alexei Verkhratsky et al.   NEUROSCIENTIST

Neurological Diseases as Primary Gliopathies: A Reassessment of Neurocentrism

(2012) Alexei Verkhratsky et al.   ASN Neuro

Astrocyte decrease in the subgenual cingulate and callosal genu in schizophrenia

(2012) Matthew Roy Williams et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Environmental enrichment prevents astroglial pathological changes in the hippocampus of APP transgenic mice, model of Alzheimer's disease

(2012) Juan Beauquis et al.   EXPERIMENTAL NEUROLOGY

Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices

(2012) Marie-Ève Tremblay et al.   GLIA

Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer’s disease

(2012) Magdalena Kulijewicz-Nawrot et al.   JOURNAL OF ANATOMY

Glial cells in (patho)physiology

(2012) Vladimir Parpura et al.   JOURNAL OF NEUROCHEMISTRY

Senescence marker protein 30 deficiency increases Parkinson's pathology by impairing astrocyte activation

(2012) Hyun Soo Kim et al.   NEUROBIOLOGY OF AGING

Effect of age on neocortical brain cells in 90+ year old human females—a cell counting study

(2012) Katrine Fabricius et al.   NEUROBIOLOGY OF AGING

Roles of glial cells in schizophrenia: Possible targets for therapeutic approaches

(2012) Nagahide Takahashi et al.   NEUROBIOLOGY OF DISEASE

Does microglial dysfunction play a role in autism and Rett syndrome?

(2012) Izumi Maezawa et al.   Neuron Glia Biology

The Neuron-Astrocyte-Microglia Triad in Normal Brain Ageing and in a Model of Neuroinflammation in the Rat Hippocampus

(2012) Francesca Cerbai et al.   PLoS One

A putative functional role for oligodendrocytes in mood regulation

(2012) N Edgar et al.   Translational Psychiatry

Alzheimer’s Disease, Neuroprotection, and CNS Immunosenescence

(2012) Wolfgang J. Streit et al.   Frontiers in Pharmacology

Age-dependent remodelling of ionotropic signalling in cortical astroglia

(2011) Ulyana Lalo et al.   AGING CELL

Early Astrocytic Atrophy in the Entorhinal Cortex of a Triple Transgenic Animal Model of Alzheimer's Disease

(2011) Chia-Yu Yeh et al.   ASN Neuro

Neuropathological abnormalities of astrocytes, GABAergic neurons, and pyramidal neurons in the dorsolateral prefrontal cortices of patients with major depressive disorder

(2011) Dong Hoon Oh et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Role of glial cells in manganese neurotoxicity

(2011) Nikolay M. Filipov et al.   JOURNAL OF APPLIED TOXICOLOGY

The Role of Microglia in the Healthy Brain

(2011) M.-E. Tremblay et al.   JOURNAL OF NEUROSCIENCE

Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

(2011) Markel Olabarria et al.   Molecular Neurodegeneration

A role for glia in the progression of Rett’s syndrome

(2011) Daniel T. Lioy et al.   NATURE

The stem cell potential of glia: lessons from reactive gliosis

(2011) Stefanie Robel et al.   NATURE REVIEWS NEUROSCIENCE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Age-related alterations in the dynamic behavior of microglia

(2010) Mausam R. Damani et al.   AGING CELL

Fragile X astrocytes induce developmental delays in dendrite maturation and synaptic protein expression

(2010) Shelley Jacobs et al.   BMC NEUROSCIENCE

Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice

(2010) Shau-Kwaun Chen et al.   CELL

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

(2010) Malgorzata Zawadzka et al.   Cell Stem Cell

Microglia Shape Adult Hippocampal Neurogenesis through Apoptosis-Coupled Phagocytosis

(2010) Amanda Sierra et al.   Cell Stem Cell

Environmental impoverishment and aging alter object recognition, spatial learning, and dentate gyrus astrocytes

(2010) Daniel G. Diniz et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice

(2010) L. Wang et al.   HUMAN MOLECULAR GENETICS

Mutant Huntingtin in Glial Cells Exacerbates Neurological Symptoms of Huntington Disease Mice

(2010) Jennifer Bradford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches

(2010) Anton I. Rosenbaum et al.   JOURNAL OF NEUROCHEMISTRY

NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease

(2010) R. B. Tripathi et al.   JOURNAL OF NEUROSCIENCE

Astrocytes Prevent Abnormal Neuronal Development in the Fragile X Mouse

(2010) S. Jacobs et al.   JOURNAL OF NEUROSCIENCE

Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate

(2010) I. Maezawa et al.   JOURNAL OF NEUROSCIENCE

Neuroglial Roots of Neurodegenerative Diseases?

(2010) José Julio Rodríguez et al.   MOLECULAR NEUROBIOLOGY

Altered expression of glutamate signaling, growth factor and glia genes in the locus coeruleus of patients with major depression

(2010) R Bernard et al.   MOLECULAR PSYCHIATRY

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

(2010) Pavel I Ortinski et al.   NATURE NEUROSCIENCE

Altered glial–neuronal crosstalk: Cornerstone in the pathogenesis of hepatic encephalopathy

(2010) Roger F. Butterworth   NEUROCHEMISTRY INTERNATIONAL

Cell cycle dynamics of NG2 cells in the postnatal and ageing brain

(2010) Konstantina Psachoulia et al.   Neuron Glia Biology

Review: The neuropathology of drug abuse

(2010) A. Büttner   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Astrocytes in Alzheimer’s disease

(2010) Alexei Verkhratsky et al.   Neurotherapeutics

Astrocyte glutamine synthetase: Importance in hyperammonemic syndromes and potential target for therapy

(2010) Saul W. Brusilow et al.   Neurotherapeutics

Functions of astrocytes and their potential as therapeutic targets

(2010) Harold K. Kimelberg et al.   Neurotherapeutics

Regulation of Oligodendrocyte Differentiation and Myelination

(2010) B. Emery   SCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease

(2010) J J Rodríguez et al.   Cell Death & Disease

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease

(2009) Wolfgang J. Streit et al.   ACTA NEUROPATHOLOGICA

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Astrocytic dysfunction: Insights on the role in neurodegeneration

(2009) Daniela Rossi et al.   BRAIN RESEARCH BULLETIN

Neuroglia in neurodegeneration

(2009) Michael T. Heneka et al.   BRAIN RESEARCH REVIEWS

Heterogeneity in astrocyte morphology and physiology

(2009) Vitali Matyash et al.   BRAIN RESEARCH REVIEWS

Loss of astrocytic glutamate transporters in Wernicke encephalopathy

(2009) Alan S. Hazell et al.   GLIA

Astrocytes in amyotrophic lateral sclerosis: direct effects on motor neuron survival

(2009) K. A. Staats et al.   JOURNAL OF BIOLOGICAL PHYSICS

Astrocytes are a major target in thiamine deficiency and Wernicke's encephalopathy

(2009) Alan S. Hazell   NEUROCHEMISTRY INTERNATIONAL

Juvenile separation stress induces rapid region- and layer-specific changes in S100ß- and glial fibrillary acidic protein–immunoreactivity in astrocytes of the rodent medial prefrontal cortex

(2009) K. Braun et al.   NEUROSCIENCE

Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression

(2009) Adolfo Sequeira et al.   PLoS One

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Focal degeneration of astrocytes in amyotrophic lateral sclerosis

(2008) D Rossi et al.   CELL DEATH AND DIFFERENTIATION

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

(2008) Akiko Nishiyama et al.   NATURE REVIEWS NEUROSCIENCE

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING

Glial Cells as Players in Parkinsonism: The “Good,” the “Bad,” and the “Mysterious” Glia

(2008) Maria A. Mena et al.   NEUROSCIENTIST

Astrocytes and Ischemic Injury

(2008) T. Takano et al.   STROKE

White matter in learning, cognition and psychiatric disorders

(2008) R. Douglas Fields   TRENDS IN NEUROSCIENCES

Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders

(2007) Jacques De Keyser et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING