Aberrant DNA methylation of microRNA genes in human breast cancer – a critical appraisal

Epigenetic Modifications in Breast Cancer and Their Role in Personalized Medicine

(2013) Olafur A. Stefansson et al.   AMERICAN JOURNAL OF PATHOLOGY

Common gene pathways and families altered by DNA methylation in breast and prostate cancers

(2013) Tanya K Day et al.   ENDOCRINE-RELATED CANCER

Faddish Stuff: Epigenetics and the Inheritance of Acquired Characteristics

(2013) Mark Ptashne   FASEB JOURNAL

The Overexpression of Hypomethylated miR-663 Induces Chemotherapy Resistance in Human Breast Cancer Cells by Targeting Heparin Sulfate Proteoglycan 2 (HSPG2)

(2013) Haiyan Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of miR-34a in breast tumors is not associated with either p53 mutations or promoter hypermethylation while it correlates with metastasis

(2013) Arash Javeri et al.   MEDICAL ONCOLOGY

Genomic and Epigenomic Cross-talks in the Regulatory Landscape of miRNAs in Breast Cancer

(2013) Devyani Samantarrai et al.   MOLECULAR CANCER RESEARCH

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis

(2013) Yun Zhang et al.   NATURE CELL BIOLOGY

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer

(2013) Sanchari Bhattacharyya et al.   NUCLEIC ACIDS RESEARCH

miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer

(2013) Lukas Vrba et al.   PLoS One

Epigenetics: Core misconcept

(2013) M. Ptashne   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-hydroxymethylcytosine and its potential roles in development and cancer

(2013) Gerd P Pfeifer et al.   Epigenetics & Chromatin

Disruption of CTCF at the miR-125b1 locus in gynecological cancers

(2012) Ernesto Soto-Reyes et al.   BMC CANCER

Human RNA Methyltransferase BCDIN3D Regulates MicroRNA Processing

(2012) Blerta Xhemalce et al.   CELL

Tet family proteins and 5-hydroxymethylcytosine in development and disease

(2012) L. Tan et al.   DEVELOPMENT

miR-10b*, a master inhibitor of the cell cycle, is down-regulated in human breast tumours

(2012) Francesca Biagioni et al.   EMBO Molecular Medicine

Genome-Wide Analysis of DNA Methylation and Expression of MicroRNAs in Breast Cancer Cells

(2012) Sumiyo Morita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNAs in the ImprintedDLK1-DIO3Region Repress the Epithelial-to-Mesenchymal Transition by Targeting the TWIST1 Protein Signaling Network

(2012) Christopher L. Haga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA methylation and microRNA dysregulation in cancer

(2012) Hiromu Suzuki et al.   Molecular Oncology

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer

(2012) E J H Wee et al.   ONCOGENE

MicroRNA-200 Family Modulation in Distinct Breast Cancer Phenotypes

(2012) María Ángeles Castilla et al.   PLoS One

A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1

(2012) Qing Xu et al.   Journal of Molecular Cell Biology

miR-125b Is Methylated and Functions as a Tumor Suppressor by Regulating the ETS1 Proto-oncogene in Human Invasive Breast Cancer

(2011) Y. Zhang et al.   CANCER RESEARCH

Analysis of MiR-195 and MiR-497 Expression, Regulation and Role in Breast Cancer

(2011) D. Li et al.   CLINICAL CANCER RESEARCH

MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer

(2011) K. J. Png et al.   GENES & DEVELOPMENT

A refined molecular taxonomy of breast cancer

(2011) M Guedj et al.   ONCOGENE

DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

(2011) P Lopez-Serra et al.   ONCOGENE

Integrated Epigenetics of Human Breast Cancer: Synoptic Investigation of Targeted Genes, MicroRNAs and Proteins upon Demethylation Treatment

(2011) Ramin Radpour et al.   PLoS One

Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas

(2011) Markus Vogt et al.   VIRCHOWS ARCHIV

Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA

(2010) Colm Nestor et al.   BIOTECHNIQUES

Let-7a regulation of insulin-like growth factors in breast cancer

(2010) Lingeng Lu et al.   BREAST CANCER RESEARCH AND TREATMENT

Epigenetically Deregulated microRNA-375 Is Involved in a Positive Feedback Loop with Estrogen Receptor   in Breast Cancer Cells

(2010) P. de Souza Rocha Simonini et al.   CANCER RESEARCH

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine

(2010) Seung-Gi Jin et al.   NUCLEIC ACIDS RESEARCH

The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

(2010) Yun Huang et al.   PLoS One

Xenoestrogen-Induced Epigenetic Repression of microRNA-9-3 in Breast Epithelial Cells

(2009) P.-Y. Hsu et al.   CANCER RESEARCH

An operational definition of epigenetics

(2009) S. L. Berger et al.   GENES & DEVELOPMENT

The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type

(2009) Britta Weigelt et al.   JOURNAL OF PATHOLOGY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Gene-Expression Signatures in Breast Cancer

(2009) Christos Sotiriou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

Epigenetic inactivation of microRNA genehsa-mir-9-1in human breast cancer

(2007) U Lehmann et al.   JOURNAL OF PATHOLOGY