Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs

Mouse Embryonic Head as a Site for Hematopoietic Stem Cell Development

(2012) Zhuan Li et al.   Cell Stem Cell

Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters

(2011) T. Yokomizo et al.   BLOOD

Embryonic origin of the adult hematopoietic system: advances and questions

(2011) A. Medvinsky et al.   DEVELOPMENT

Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region

(2011) Andrejs Ivanovs et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

(2011) Stanislav Rybtsov et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters

(2010) A. C. Zovein et al.   BLOOD

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos

(2010) T. Yokomizo et al.   DEVELOPMENT

Tel1/ETV6 Specifies Blood Stem Cells through the Agency of VEGF Signaling

(2010) Aldo Ciau-Uitz et al.   DEVELOPMENTAL CELL

Hematopoietic stem cell activity in the aorta-gonad-mesonephros region enhances after mid-day 11 of mouse development

(2010) Erin Taylor et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The Notch pathway in the developing hematopoietic system

(2010) Anna Bigas et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Histology Atlas of the Developing Mouse Hepatobiliary System with Emphasis on Embryonic Days 9.5-18.5

(2010) Laura Wilding Crawford et al.   TOXICOLOGIC PATHOLOGY

Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development

(2009) M. Peeters et al.   DEVELOPMENT

Hedgehog and Bmp Polarize Hematopoietic Stem Cell Emergence in the Zebrafish Dorsal Aorta

(2009) Robert N. Wilkinson et al.   DEVELOPMENTAL CELL

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Continuous single-cell imaging of blood generation from haemogenic endothelium

(2009) Hanna M. Eilken et al.   NATURE

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

Restoration of Runx1 Expression in the Tie2 Cell Compartment Rescues Definitive Hematopoietic Stem Cells and Extends Life of Runx1 Knockout Animals Until Birth

(2009) Anna Liakhovitskaia et al.   STEM CELLS

The Emergence of Hematopoietic Stem Cells Is Initiated in the Placental Vasculature in the Absence of Circulation

(2008) Katrin E. Rhodes et al.   Cell Stem Cell

Extensive Hematopoietic Stem Cell Generation in the AGM Region via Maturation of VE-Cadherin+CD45+ Pre-Definitive HSCs

(2008) Samir Taoudi et al.   Cell Stem Cell

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1

(2008) Àlex Robert-Moreno et al.   EMBO JOURNAL

Three-Dimensional Analysis of Vascular Development in the Mouse Embryo

(2008) Johnathon R. Walls et al.   PLoS One

Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells

(2007) G. Ghiaur et al.   BLOOD