Hippocampal neurogenesis: a biomarker for depression or antidepressant effects? Methodological considerations and perspectives for future research

The hippocampal–prefrontal pathway: The weak link in psychiatric disorders?

(2013) Bill P. Godsil et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Glucocorticoids Orchestrate Divergent Effects on Mood through Adult Neurogenesis

(2013) M. L. Lehmann et al.   JOURNAL OF NEUROSCIENCE

Sustained remission from depressive-like behavior depends on hippocampal neurogenesis

(2013) A Mateus-Pinheiro et al.   Translational Psychiatry

Hippocampal Angiogenesis and Progenitor Cell Proliferation Are Increased with Antidepressant Use in Major Depression

(2012) Maura Boldrini et al.   BIOLOGICAL PSYCHIATRY

Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion

(2012) Toshiaki Nakashiba et al.   CELL

Adult-born hippocampal neurons promote cognitive flexibility in mice

(2012) Nesha S. Burghardt et al.   HIPPOCAMPUS

The Vasopressin V1bReceptor Antagonist SSR149415 in the Treatment of Major Depressive and Generalized Anxiety Disorders

(2012) Guy Griebel et al.   JOURNAL OF CLINICAL PSYCHIATRY

Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?

(2012) Guy Griebel et al.   NATURE REVIEWS DRUG DISCOVERY

Neurogenesis-Independent Antidepressant-Like Effects on Behavior and Stress Axis Response of a Dual Orexin Receptor Antagonist in a Rodent Model of Depression

(2012) Mathieu Nollet et al.   NEUROPSYCHOPHARMACOLOGY

The neurobiology of depression and antidepressant action

(2012) Paul Willner et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Depression and Hippocampal Neurogenesis: A Road to Remission?

(2012) A. J. Eisch et al.   SCIENCE

Requirement of adult-born neurons for hippocampus-dependent learning

(2011) Antonia Marín-Burgin et al.   BEHAVIOURAL BRAIN RESEARCH

Adult neurogenesis and the plasticity of the dentate gyrus network

(2011) Lucas A. Mongiat et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

In vivo imaging of adult neurogenesis

(2011) Sebastien Couillard-Despres et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Lithium, but Not Fluoxetine or the Corticotropin-Releasing Factor Receptor 1 Receptor Antagonist R121919, Increases Cell Proliferation in the Adult Dentate Gyrus

(2011) N. D. Hanson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Basolateral amygdala regulation of adult hippocampal neurogenesis and fear-related activation of newborn neurons

(2011) E D Kirby et al.   MOLECULAR PSYCHIATRY

Antidepressants recruit new neurons to improve stress response regulation

(2011) A Surget et al.   MOLECULAR PSYCHIATRY

Adult hippocampal neurogenesis buffers stress responses and depressive behaviour

(2011) Jason S. Snyder et al.   NATURE

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

An analysis of rat prefrontal cortex in mediating executive function

(2011) Raymond P. Kesner et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Characterization of 5-HT1A/1B−/− mice: An animal model sensitive to anxiolytic treatments

(2011) Jean-Philippe Guilloux et al.   NEUROPHARMACOLOGY

The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

(2011) David Petrik et al.   NEUROPHARMACOLOGY

Selective Deletion of a Cell Cycle Checkpoint Kinase (ATR) Reduces Neurogenesis and Alters Responses in Rodent Models of Behavioral Affect

(2011) Jennifer L Onksen et al.   NEUROPSYCHOPHARMACOLOGY

Depression, Antidepressants and Neurogenesis: A Critical Reappraisal

(2011) Nicola D Hanson et al.   NEUROPSYCHOPHARMACOLOGY

When Are New Hippocampal Neurons, Born in the Adult Brain, Integrated into the Network That Processes Spatial Information?

(2011) C. Jimena Sandoval et al.   PLoS One

Necessity of Hippocampal Neurogenesis for the Therapeutic Action of Antidepressants in Adult Nonhuman Primates

(2011) Tarique D. Perera et al.   PLoS One

The design of new antidepressants

(2010) Catherine Belzung et al.   BEHAVIOURAL PHARMACOLOGY

Learning as a Model for Neural Plasticity in Major Depression

(2010) Christoph Nissen et al.   BIOLOGICAL PSYCHIATRY

Open questions in current models of antidepressant action

(2010) A Tanti et al.   BRITISH JOURNAL OF PHARMACOLOGY

Adult-born neurons are necessary for extended contextual discrimination

(2010) Sophie Tronel et al.   HIPPOCAMPUS

Intermittent Hypoxia Promotes Hippocampal Neurogenesis and Produces Antidepressant-Like Effects in Adult Rats

(2010) X.-H. Zhu et al.   JOURNAL OF NEUROSCIENCE

Environmental enrichment requires adult neurogenesis to facilitate the recovery from psychosocial stress

(2010) R J Schloesser et al.   MOLECULAR PSYCHIATRY

Implications of the Functional Integration of Adult-Born Hippocampal Neurons in Anxiety-Depression Disorders

(2010) Denis J. David et al.   NEUROSCIENTIST

Deletion of Running-Induced Hippocampal Neurogenesis by Irradiation Prevents Development of an Anxious Phenotype in Mice

(2010) Johannes Fuss et al.   PLoS One

Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance

(2010) D. C. Lagace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is There a Role for Neurogenesis in Depression?

(2009) Peter Gass et al.   BIOLOGICAL PSYCHIATRY

Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic-like symptoms in rats

(2009) M.N. Jayatissa et al.   BRAIN RESEARCH

Conditional ablation and recovery of forebrain neurogenesis in the mouse

(2009) Benjamin H. Singer et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

(2009) W. Deng et al.   JOURNAL OF NEUROSCIENCE

Adult-Born Hippocampal Neurons Are More Numerous, Faster Maturing, and More Involved in Behavior in Rats than in Mice

(2009) J. S. Snyder et al.   JOURNAL OF NEUROSCIENCE

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

(2009) S. Jessberger et al.   LEARNING & MEMORY

Ageing abolishes the effects of fluoxetine on neurogenesis

(2009) S Couillard-Despres et al.   MOLECULAR PSYCHIATRY

Adult hippocampal neurogenesis is involved in anxiety-related behaviors

(2009) J-M Revest et al.   MOLECULAR PSYCHIATRY

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Antidepressants increase neural progenitor cells in the human hippocampus

(2009) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response

(2009) Robert J. Schloesser et al.   NEUROREPORT

Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies

(2009) Alexander Garthe et al.   PLoS One

Recruitment of adult-generated neurons into functional hippocampal networks contributes to updating and strengthening of spatial memory

(2009) S. Trouche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A critical review of chronic stress effects on spatial learning and memory

(2009) Cheryl D. Conrad   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

Drug-Dependent Requirement of Hippocampal Neurogenesis in a Model of Depression and of Antidepressant Reversal

(2008) Alexandre Surget et al.   BIOLOGICAL PSYCHIATRY

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Development of neural stem cell in the adult brain

(2008) Xin Duan et al.   CURRENT OPINION IN NEUROBIOLOGY

Effects of vagus nerve stimulation on rat hippocampal progenitor proliferation

(2008) David Revesz et al.   EXPERIMENTAL NEUROLOGY

Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells

(2008) J.-W. Wang et al.   JOURNAL OF NEUROSCIENCE

The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling

(2008) J M Bessa et al.   MOLECULAR PSYCHIATRY

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

(2008) David Dupret et al.   PLoS One

Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatment

(2008) N. Elizalde et al.   PSYCHOPHARMACOLOGY

The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for?

(2008) Gerd Kempermann   TRENDS IN NEUROSCIENCES

The Timing of Differentiation of Adult Hippocampal Neurons Is Crucial for Spatial Memory

(2008) Stefano Farioli-Vecchioli et al.   PLOS BIOLOGY

Dissociations across the dorsal–ventral axis of CA3 and CA1 for encoding and retrieval of contextual and auditory-cued fear

(2007) Michael R. Hunsaker et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: The role of glycogen-synthase-kinase-3β

(2007) R. Silva et al.   NEUROSCIENCE