Dual role of lipoproteins in endothelial cell dysfunction in atherosclerosis

Anti-oxidant and anti-inflammatory mechanisms of amlodipine action to improve endothelial cell dysfunction induced by irreversibly glycated LDL

(2011) Laura Toma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state

(2011) K. Chen et al.   BLOOD

Modified Low Density Lipoproteins Decrease the Activity and Expression of Lysosomal Acid Lipase in Human Endothelial and Smooth Muscle Cells

(2011) Constantina Heltianu et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Evolving Concepts of the Role of High-Density Lipoprotein in Protection from Atherosclerosis

(2011) John A. Farmer et al.   Current Atherosclerosis Reports

Ellagic Acid Inhibits Oxidized Low-Density Lipoprotein (OxLDL)-Induced Metalloproteinase (MMP) Expression by Modulating the Protein Kinase C-α/Extracellular Signal-Regulated Kinase/Peroxisome Proliferator-Activated Receptor γ/Nuclear Factor-κB (PKC-α/ERK/PPAR-γ/NF-κB) Signaling Pathway in Endothelial Cells

(2011) Mei-Ying Kuo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 and its Soluble Form: Cardiovascular Implications

(2011) Teresa Navarra et al.   Journal of Atherosclerosis and Thrombosis

Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease

(2011) Christian Besler et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of IL-33 in inflammation and disease

(2011) Ashley M Miller   Journal of Inflammation-London

Protective effect of HDL on endothelial NO production: the role of DDAH/ADMA pathway

(2011) Zhen-yu Peng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Lipoproteínas, plaquetas y aterotrombosis

(2011) Lina Badimón et al.   REVISTA ESPANOLA DE CARDIOLOGIA

ROCK2 associates with lectin-like oxidized LDL receptor-1 and mediates oxidized LDL-induced IL-8 production

(2010) Mark D. Mattaliano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effects of high-density lipoprotein on endothelium-dependent vasorelaxation

(2010) Richard M. McAllister et al.   Applied Physiology Nutrition and Metabolism

ATP-Binding Cassette Transporter G1 and High-Density Lipoprotein Promote Endothelial NO Synthesis Through a Decrease in the Interaction of Caveolin-1 and Endothelial NO Synthase

(2010) Naoki Terasaka et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Niacin results in reduced monocyte adhesion in patients with type 2 diabetes mellitus

(2010) S. Tavintharan et al.   ATHEROSCLEROSIS

Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) by 15-lipoxygenase-modified LDL in endothelial cells

(2010) Angela Pirillo et al.   ATHEROSCLEROSIS

OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling

(2010) Sungwoo Ryoo et al.   ATHEROSCLEROSIS

HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs

(2010) C Muller et al.   CELL DEATH AND DIFFERENTIATION

High-Density Lipoprotein-Mediated Anti-Atherosclerotic and Endothelial-Protective Effects: A Potential Novel Therapeutic Target in Cardiovascular Disease

(2010) Christian Besler et al.   CURRENT PHARMACEUTICAL DESIGN

Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo

(2010) Y. Dong et al.   DIABETES

Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases

(2010) F. Engin et al.   DIABETES OBESITY & METABOLISM

Involvement of RAGE, NADPH Oxidase, and Ras/Raf-1 Pathway in Glycated LDL-Induced Expression of Heat Shock Factor-1 and Plasminogen Activator Inhibitor-1 in Vascular Endothelial Cells

(2010) Ganesh V. Sangle et al.   ENDOCRINOLOGY

Pathological aspects of lipid peroxidation

(2010) Anne Negre-Salvayre et al.   FREE RADICAL RESEARCH

Nitric oxide – the endothelium-derived relaxing factor and its role in endothelial functions

(2010) V. Bauer et al.   GENERAL PHYSIOLOGY AND BIOPHYSICS

The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation

(2010) Yoshiro Kobayashi   JOURNAL OF LEUKOCYTE BIOLOGY

HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate

(2010) Mi-Hye Lee et al.   JOURNAL OF LIPID RESEARCH

VLDL hydrolysis by LPL activates PPAR-α through generation of unbound fatty acids

(2010) Maxwell A. Ruby et al.   JOURNAL OF LIPID RESEARCH

Down-regulation of endothelial TLR4 signalling after apo A-I gene transfer contributes to improved survival in an experimental model of lipopolysaccharide-induced inflammation

(2010) Sophie Van Linthout et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis

(2010) Min Jun et al.   LANCET

Endoplasmic reticulum stress and atherosclerosis

(2010) Gökhan S Hotamisligil   NATURE MEDICINE

Cellular signaling and NO production

(2010) Thomas Michel et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Deletion of the Basement Membrane Heparan Sulfate Proteoglycan Type XVIII Collagen Causes Hypertriglyceridemia in Mice and Humans

(2010) Joseph R. Bishop et al.   PLoS One

Degradation of the endothelial glycocalyx is associated with chylomicron leakage in mouse cremaster muscle microcirculation

(2010) Alina Constantinescu et al.   THROMBOSIS AND HAEMOSTASIS

Basic Science Review: Statin Therapy-Part I: The Pleiotropic Effects of Statins in Cardiovascular Disease

(2010) Benjamin Sadowitz et al.   Vascular and Endovascular Surgery

Ceruloplasmin and oxidized LDL colocalize in atherosclerotic lesions of hamster

(2010) Camelia Stancu et al.   Open Life Sciences

LOX-1-dependent transcriptional regulation in response to oxidized LDL treatment of human aortic endothelial cells

(2009) Mark D. Mattaliano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose

(2009) Laura Toma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nox4 overexpression activates reactive oxygen species and p38 MAPK in human endothelial cells

(2009) Claudia Goettsch et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells

(2009) Koichi Sugimoto et al.   CARDIOVASCULAR RESEARCH

Quantitative Trait Locus Mapping and Identification of Zhx2 as a Novel Regulator of Plasma Lipid Metabolism

(2009) Peter S. Gargalovic et al.   Circulation-Cardiovascular Genetics

Transendothelial lipoprotein transport and regulation of endothelial permeability and integrity by lipoproteins

(2009) Arnold von Eckardstein et al.   CURRENT OPINION IN LIPIDOLOGY

Variation in paraoxonase-1 activity and atherosclerosis

(2009) Handrean Soran et al.   CURRENT OPINION IN LIPIDOLOGY

HDL as a Biomarker, Potential Therapeutic Target, and Therapy: FIG. 1.

(2009) Mohamad Navab et al.   DIABETES

A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids

(2009) Sangderk Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardiac Hypertrophy During Hypercholesterolemia and Its Amelioration With Rosuvastatin and Amlodipine

(2009) Bum-Yong Kang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+signaling pathways in endothelial cells

(2009) Nobuo Sakamoto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Comparative efficacy and safety of amlodipine/benazepril combination therapy and amlodipine monotherapy in severe hypertension

(2009) J L Izzo et al.   JOURNAL OF HUMAN HYPERTENSION

CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

(2009) R. L. Silverstein et al.   Science Signaling

Abdominal Obesity and the Metabolic Syndrome: Contribution to Global Cardiometabolic Risk

(2008) Jean-Pierre Després et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Glycoxidized LDL increases lectin-like oxidized low density lipoprotein receptor-1 in diabetes mellitus

(2008) Sammy W.M. Shiu et al.   ATHEROSCLEROSIS

Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high density lipoproteins

(2008) Sanjay Patel et al.   ATHEROSCLEROSIS

Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells

(2008) Shobha H. Ganji et al.   ATHEROSCLEROSIS

Novel aspects of postprandial lipemia in relation to atherosclerosis

(2008) A. Alipour et al.   ATHEROSCLEROSIS SUPPLEMENTS

The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

(2008) Sarah Dunn et al.   BIOCHEMICAL JOURNAL

Endothelial transcytosis in health and disease

(2008) Maya Simionescu et al.   CELL AND TISSUE RESEARCH

Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees

(2008) Elisabetta Dejana et al.   CELL AND TISSUE RESEARCH

Vascular endothelium in atherosclerosis

(2008) Anca V. Sima et al.   CELL AND TISSUE RESEARCH

The Scavenger Receptor Class B Type I Adaptor Protein PDZK1 Maintains Endothelial Monolayer Integrity

(2008) Weifei Zhu et al.   CIRCULATION RESEARCH

Oxidized Low-Density Lipoproteins Trigger Endoplasmic Reticulum Stress in Vascular Cells

(2008) Marie Sanson et al.   CIRCULATION RESEARCH

Glycation as an atherogenic modification of LDL

(2008) Nahla Younis et al.   CURRENT OPINION IN LIPIDOLOGY

Differential vascular functions of Nox family NADPH oxidases

(2008) Ralf P Brandes et al.   CURRENT OPINION IN LIPIDOLOGY

Glycation of paraoxonase-1 inhibits its activity and impairs the ability of high-density lipoprotein to metabolize membrane lipid hydroperoxides

(2008) M. Mastorikou et al.   DIABETIC MEDICINE

Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice

(2008) Alexander Riad et al.   EUROPEAN JOURNAL OF HEART FAILURE

Endothelial cell regulation by phospholipid oxidation products

(2008) Judith A. Berliner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of transcription factors and gene expression by oxidized low-density lipoprotein

(2008) Cécile Mazière et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of oxidative stress and nitric oxide in atherothrombosis

(2008) Edith Lubos   Frontiers in Bioscience-Landmark

Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase

(2008) Yunzhou Dong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet

(2008) Naoki Terasaka et al.   JOURNAL OF CLINICAL INVESTIGATION

Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation

(2008) Limin Wang et al.   JOURNAL OF LIPID RESEARCH

Impaired glycocalyx barrier properties contribute to enhanced intimal low-density lipoprotein accumulation at the carotid artery bifurcation in mice

(2008) Bernard M. van den Berg et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY