Article
Environmental Sciences
Khadija Sossey Alaoui, Bernard Tychon, Sandrine Joachim, Alain Geffard, Katherine Nott, Sebastien Ronkart, Jean-Marc Porcher, Remy Beaudouin, Christelle Robert, Marie-Laure Fauconnier, Matthew Saive
Summary: The study aimed to assess the toxicity of a mixture of five pharmaceutical drugs using Fontinalis antipyretica as a bioindicator and bioaccumulator. Results showed that only carbamazepine and irbesartan were accumulated by the species, with bioaccumulation levels increasing with exposure time. Antioxidant enzymes were sensitive to the drug mixture, with higher activity observed in plants exposed to higher concentrations. Chlorophyll content decreased in exposed plants, but photosynthetic activity was restored after 5 months. Morphological characteristics were less impacted by the treatment.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Biochemistry & Molecular Biology
Han-Mei Du, Chan Liu, Xin-Wu Jin, Cheng-Feng Du, Yan Yu, Shuai Luo, Wen-Zhu He, Su-Zhi Zhang
Summary: Aluminum (Al) toxicity is a major constraint for plant growth and cereal crop yield in acidic soils. This study identified a maize ALDH gene, ZmALDH, which is involved in protection against Al-induced oxidative stress. Overexpression of ZmALDH in Arabidopsis increased Al tolerance by promoting antioxidant mechanisms and reducing Al accumulation in roots.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Abderrahmen Merghni, Ahmed Reda Belmamoun, Adriana Cristina Urcan, Otilia Bobis, Mohamed Ali Lassoued
Summary: This study investigated the bactericidal mechanism of 1,8-cineol against MRSA. The results showed that 1,8-cineol exhibited antibacterial efficacy with a minimum inhibitory concentration of 7.23 mg/mL. Additionally, it caused membrane permeability changes and induced oxidative stress in MRSA cells, leading to its antimicrobial effect.
Article
Plant Sciences
Arnon Afonso de Souza Cardoso, Fabricio Teixeira de Lima Gomes, Joao Renato Rodrigues Antonio, Luiz Roberto Guimaraes Guilherme, Jiping Liu, Li Li, Maria Ligia de Souza Silva
Summary: The interaction between selenium and sulfur in plants and soils is important to study as it affects selenium nutrition and toxicity, crop composition and production, and the risk of toxicity to humans and animals. This study evaluated the impact of selenium exposure on rice plants grown under different sulfur supplies at different growth stages. The results showed that sulfate supply alleviated selenate toxicity, while soil clay content influenced selenate availability and adsorption capacity.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2022)
Review
Cell Biology
Domenico Lapenna
Summary: Glutathione (GSH) is an important low-molecular weight thiol nucleophile and reductant with multiple functions, including antioxidant protection, detoxification, and cell signaling. It works in concert with GSH-dependent enzymes and its levels decline during aging, although elevated GSH levels in elderly individuals with good health suggest a potential link to increased healthspan and lifespan.
AGEING RESEARCH REVIEWS
(2023)
Article
Nutrition & Dietetics
Grazyna Swiderska-Kolacz, Malgorzata Jefimow, Jolanta Klusek, Norbert Raczka, Szymon Zmorzynski, Anna Wojciechowska, Iwona Stanislawska, Marek Lyp, Joanna Czerwik-Marcinkowska
Summary: This study found that diet supplementation with Pinnularia borealis could lower cholesterol and triacylglycerol concentrations in the liver and kidneys of mice, indicating the protective properties of algae. Additionally, even a low concentration of Pinnularia borealis was sufficient to improve antioxidant capacity.
Review
Biochemistry & Molecular Biology
Evangelia Eirini Tsermpini, Una Glamoclija, Fulden Ulucan-Karnak, Sara Redensek Trampuz, Vita Dolzan
Summary: This article highlights the critical role of oxidative stress in COVID-19, discussing genetic variants within the oxidative stress pathway associated with the disease and exploring the use of antioxidant therapies in clinical trials for COVID-19 treatment, particularly glutathione and N-acetylcysteine.
Article
Environmental Sciences
Megha Murali, T. Shivanandappa
Summary: Endosulfan exposure causes high levels of oxidative stress in the liver and brain, leading to reduced antioxidant enzyme activity and increased ROS and lipid peroxidation. The brain is more susceptible to oxidative stress than the liver, likely due to its lower antioxidant defenses and higher oxygen consumption.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Chemistry, Medicinal
Marlena Brzozowa-Zasada, Adam Piecuch, Karolina Bajdak-Rusinek, Kamil Janelt, Marek Michalski, Olesya Klymenko, Natalia Matysiak
Summary: Studies have shown that the expression of Gpx-1 is associated with cancer development and its role in regulating reactive oxygen species levels. This study aimed to investigate the expression of Gpx-1 in colon adenocarcinoma patients in Poland. Immunohistochemical analysis revealed that high expression of Gpx-1 was associated with tumor grade, PCNA expression, invasion depth, and angioinvasion (all p < 0.001). High expression of Gpx-1 was correlated with poor prognosis in colon adenocarcinoma patients.
Article
Immunology
Ebenezer O. O. Farombi, Babajide O. O. Ajayi, Edward K. K. Opata, Abisoye O. O. Fafioye, Adetomilola T. T. Akinade
Summary: In this study, the effect of Kolaviron on testosterone-induced BPH in rats was investigated. The results showed that Kolaviron can prevent the development of BPH by inhibiting hormone activity, reducing oxidative stress, and inflammation. The study found that Kolaviron prevents BPH through regulation of androgen/androgen receptor signaling and anti-oxidative and anti-inflammatory mechanisms.
INFLAMMOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Fan Li, Xiaojing Wu, Hongli Liu, Mengqi Liu, Zhengkai Yue, Zhenyu Wu, Lei Liu, Fuchang Li
Summary: This study reveals that copper depletion enhances ferroptosis by causing mitochondrial perturbation and reducing antioxidative mechanisms.
Article
Environmental Sciences
Megan E. Solan, Camryn P. Koperski, Sanjanaa Senthilkumar, Ramon Lavado
Summary: This study investigates the effects of five short-chain PFAS compounds on oxidative stress biomarkers in vitro, finding that all short-chain PFAS compounds except for PFHxS increase the activity of at least one antioxidant enzyme.
ENVIRONMENTAL RESEARCH
(2023)
Article
Agronomy
Aihua Wang, Chao Ma, Hongye Ma, Zhilang Qiu, Xiaopeng Wen
Summary: The study compared the physiological and proteomic responses of pitaya under drought stress, revealing enhanced antioxidant enzyme activities and activation of metabolic pathways to cope with stress. The findings provide insights into the mechanisms underlying pitaya's considerable tolerance to drought stress.
Article
Environmental Sciences
Agnieszka Krzyszczak, Michal Dybowski, Izabela Josko, Magdalena Kusiak, Malgorzata Sikora, Bozena Czech
Summary: The impact of biochar on barley growth was assessed, and it was found that despite the low concentration of PAHs and their derivatives, oxidative stress was still induced in the plants.
ENVIRONMENTAL POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Alica Pizent, Milena Andelkovic, Blanka Tariba Lovakovic, Tanja Zivkovic Semren, Aleksandra Buha Djordjevic, Marija Gamulin, Vera Bonderovic, Miodrag Acimovic, Zorica Bulat
Summary: Higher blood Hg, SOD, and GPx levels and lower serum SH levels were found in prostate cancer patients compared to controls. Significant correlations between oxidative stress parameters and metal concentrations suggest a potential role of metal-induced oxidative stress in prostate cancer.
Article
Neurosciences
Kevin Mouzat, Nicolas Molinari, Jovana Kantar, Anne Polge, Philippe Corcia, Philippe Couratier, Pierre Clavelou, Raul Juntas-Morales, Nicolas Pageot, Jean-Marc A. Lobaccaro, Cedric Raoul, Serge Lumbroso, William Camu
MOLECULAR NEUROBIOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Bagora Bayala, Imael H. N. Bassole, Salwan Maqdasy, Silvere Baron, Jacques Simpore, Jean-Marc A. Lobaccaro
Article
Biology
Stephane Grison, Ghada Elmhiri, Celine Gloaguen, Christelle Elie, Dimitri Kereselidze, Karine Tack, Philippe Lestaevel, Audrey Legendre, Line Manens, Mohamed Amine Benadjaoud, Jean-Marc Lobaccaro, Maamar Souidi
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2018)
Retraction
Multidisciplinary Sciences
Anthony Alioui, Julie Dufour, Valerio Leoni, Anke Loregger, Martina Moeton, Luigi Iuliano, Chiara Zerbinati, Amandine Septier, Pierre Val, Allan Fouache, Vincenzo Russo, David H. Volle, Jean-Marc A. Lobaccaro, Noam Zelcer, Silvere Baron
NATURE COMMUNICATIONS
(2018)
Article
Multidisciplinary Sciences
Normand Podechard, Simon Ducheix, Arnaud Polizzi, Frederic Lasserre, Alexandra Montagner, Vincent Legagneux, Edwin Fouche, Fabrice Saez, Jean-Marc Lobaccaro, Laila Lakhal, Sandrine Ellero-Simatos, Pascal. G. Martin, Nicolas Loiseau, Justine Bertrand-Michel, Herve Guillou
SCIENTIFIC REPORTS
(2018)
Review
Endocrinology & Metabolism
Lauriane Sedes, Laura Thirouard, Salwan Maqdasy, Manon Garcia, Francoise Caira, Jean-Marc A. Lobaccaro, Claude Beaudoin, David H. Volle
FRONTIERS IN ENDOCRINOLOGY
(2018)
Review
Biochemistry & Molecular Biology
Sarah Dallel, Igor Tauveron, Florence Brugnon, Silvere Baron, Jean Marc A. Lobaccaro, Salwan Maqdasy
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2018)
Review
Biochemistry & Molecular Biology
Laura Bousset, Amandine Rambur, Allan Fouache, Julio Bunay, Laurent Morel, Jean-Marc A. Lobaccaro, Silvere Baron, Amalia Trousson, Cyrille de Joussineau
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2018)
Article
Toxicology
Marion Regnier, Arnaud Polizzi, Celine Lukowicz, Sarra Smati, Frederic Lasserre, Yannick Lippi, Claire Naylies, Joelle Laffitte, Colette Betoulieres, Alexandra Montagner, Simon Ducheix, Pascal Gourbeyre, Sandrine Ellero-Simatos, Sandrine Menard, Justine Bertrand-Michel, Talal Al Saati, Jean-Marc Lobaccaro, Hester M. Burger, Wentzel C. Gelderblom, Herve Guillou, Isabelle P. Oswald, Nicolas Loiseau
ARCHIVES OF TOXICOLOGY
(2019)
Article
Gastroenterology & Hepatology
Simon Ducheix, Claudia Peres, Jennifer Hardfeldt, Carla Frau, Gabriele Mocciaro, Elena Piccinin, Jean-Marc Lobaccaro, Stefania De Santis, Marcello Chieppa, Justine Bertrand-Michel, Michelina Plateroti, Julian L. Griffin, Carlo Sabba, James M. Ntambi, Antonio Moschetta
Review
Biochemistry & Molecular Biology
Bagora Bayala, Abdou Azaque Zoure, Silvere Baron, Cyrille de Joussineau, Jacques Simpore, Jean-Marc A. Lobaccaro
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Endocrinology & Metabolism
Jean-Marc Lobaccaro, Salwan Maqdasy, Jean-Paul Saru, Silvere Baron, David H. Volle
CORRESPONDANCES EN METABOLISMES HORMONES DIABETES ET NUTRITION
(2018)
Meeting Abstract
Clinical Neurology
S. Vigne, F. Chalmin, D. Duc, A. Clottu, J. -M. Lobaccaro, C. Pot
MULTIPLE SCLEROSIS JOURNAL
(2017)
Review
Biochemistry & Molecular Biology
Zangbewende Guy Ouedraogo, Allan Fouache, Amalia Trousson, Silvere Baron, Jean-Marc A. Lobaccaro
CHEMISTRY AND PHYSICS OF LIPIDS
(2017)
Article
Hematology
Jessica Kristine Nelson, Duco Steven Koenis, Saskia Scheij, Emma Clare Laura Cook, Martina Moeton, Ana Santos, Jean-Marc Adolphe Lobaccaro, Silvere Baron, Noam Zelcer
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2017)
