Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents

Propafenone blocks human cardiac Kir2.x channels by decreasing the negative electrostatic charge in the cytoplasmic pore

(2013) Irene Amorós et al.   BIOCHEMICAL PHARMACOLOGY

Rotors and the Dynamics of Cardiac Fibrillation

(2013) Sandeep V. Pandit et al.   CIRCULATION RESEARCH

KCNJ2mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia

(2013) Makarand Deo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic atrial fibrillation up-regulates β1-Adrenoceptors affecting repolarizing currents and action potential duration

(2012) Marta González de la Fuente et al.   CARDIOVASCULAR RESEARCH

Inhibition of Cardiac Ca 2+ Release Channels (RyR2) Determines Efficacy of Class I Antiarrhythmic Drugs in Catecholaminergic Polymorphic Ventricular Tachycardia

(2011) Hyun Seok Hwang et al.   Circulation-Arrhythmia and Electrophysiology

Flecainide Therapy Reduces Exercise-Induced Ventricular Arrhythmias in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

(2011) Christian van der Werf et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel

(2010) TP De Boer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Left-to-Right Atrial Inward Rectifier Potassium Current Gradients in Patients With Paroxysmal Versus Chronic Atrial Fibrillation

(2010) Niels Voigt et al.   Circulation-Arrhythmia and Electrophysiology

Kir 2.1 channelopathies: the Andersen–Tawil syndrome

(2010) Martin Tristani-Firouzi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Flecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectification

(2010) R. Caballero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitric Oxide Increases Cardiac I K1 by Nitrosylation of Cysteine 76 of Kir2.1 Channels

(2009) Ricardo Gómez et al.   CIRCULATION RESEARCH

Cardiac strong inward rectifier potassium channels

(2009) Justus M.B. Anumonwo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation

(2009) Niels Voigt et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Reduction of complex ventricular ectopy and improvement in exercise capacity with flecainide therapy in Andersen-Tawil syndrome

(2008) D. J. Fox et al.   EUROPACE