Journal
JOURNAL OF ETHNOPHARMACOLOGY
Volume 171, Issue -, Pages 231-239Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.jep.2015.05.049
Keywords
Lonicera japonica; Sepsis; Immunosuppression; Lymphocyte apoptosis; Th1/Th2 cytokine
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Funding
- Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea [HI12C1701(A121826)]
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Ethnopharmacological relevance: Lonicera japonica Thunberg, a widely used traditional Chinese medicine, possesses antibacterial, antiviral, and antiendotoxin activities. This study investigated the molecular mechanisms of HS-23, the ethanol extract of the dried flower buds of L japonica, on sepsis-induced immunosuppression. Materials and methods: Male ICR mice were intravenously administered HS-23 (10, 20, and 40 mg/1
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