Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells

Gemcitabine-Based Chemogene Therapy for Pancreatic Cancer Using Ad-dCK::UMK GDEPT and TS/RR siRNA Strategies

(2015) Soukaina Réjiba et al.   NEOPLASIA

Interdependence of Gemcitabine Treatment, Transporter Expression, and Resistance in Human Pancreatic Carcinoma Cells

(2015) Wolfgang Hagmann et al.   NEOPLASIA

Adjuvant Chemotherapy With Gemcitabine and Long-term Outcomes Among Patients With Resected Pancreatic Cancer

(2013) Helmut Oettle et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

The Dark Side of E2F1: In Transit beyond Apoptosis

(2012) D. Engelmann et al.   CANCER RESEARCH

Targeting of Several Glycolytic Enzymes Using RNA Interference Reveals Aldolase Affects Cancer Cell Proliferation through a Non-glycolytic Mechanism

(2012) Carolyn Ritterson Lew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of a Novel Class of Glucose Transporter Inhibitors

(2012) Dasheng Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting the Oncogenic E3 Ligase Skp2 in Prostate and Breast Cancer Cells with a Novel Energy Restriction-Mimetic Agent

(2012) Shuo Wei et al.   PLoS One

Functional Metabolic Screen Identifies 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 as an Important Regulator of Prostate Cancer Cell Survival

(2012) Susana Ros et al.   Cancer Discovery

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ

(2011) Diana Whitaker-Menezes et al.   CELL CYCLE

miR-34a Induces the Downregulation of Both E2F1 and B-Myb Oncogenes in Leukemic Cells

(2011) G. Zauli et al.   CLINICAL CANCER RESEARCH

Energy Restriction-mimetic Agents Induce Apoptosis in Prostate Cancer Cells in Part through Epigenetic Activation of KLF6 Tumor Suppressor Gene Expression

(2011) Chun-Han Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Damage Signals through Differentially Modified E2F1 Molecules To Induce Apoptosis

(2011) J. Carnevale et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

MicroRNA-520e suppresses growth of hepatoma cells by targeting the NF-κB-inducing kinase (NIK)

(2011) S Zhang et al.   ONCOGENE

MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways

(2011) I Keklikoglou et al.   ONCOGENE

GLUT-1 Expression in Pancreatic Neoplasia

(2011) Olca Basturk et al.   PANCREAS

MicroRNAs MiR-17, MiR-20a, and MiR-106b Act in Concert to Modulate E2F Activity on Cell Cycle Arrest during Neuronal Lineage Differentiation of USSC

(2011) Hans-Ingo Trompeter et al.   PLoS One

Molecular predictors of gemcitabine response in pancreatic cancer

(2011) Ioannis A Voutsadakis   World Journal of Gastrointestinal Oncology

hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion and side populations

(2010) F Wang et al.   BRITISH JOURNAL OF CANCER

Energy Restriction as an Antitumor Target of Thiazolidinediones

(2010) Shuo Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Implication of Checkpoint Kinase-dependent Up-regulation of Ribonucleotide Reductase R2 in DNA Damage Response

(2009) Yong-Wei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CDK4–pRB–E2F1 pathway controls insulin secretion

(2009) Jean-Sébastien Annicotte et al.   NATURE CELL BIOLOGY

MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation

(2009) K-H Lee et al.   ONCOGENE

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance

(2008) Chun-Wun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression

(2008) M T Pickering et al.   ONCOGENE