The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis

The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp–Csk–Src pathway

(2013) Javier Rey-Barroso et al.   CELLULAR SIGNALLING

Dioxin Receptor Expression Inhibits Basal and Transforming Growth Factor β-induced Epithelial-to-mesenchymal Transition

(2013) Eva M. Rico-Leo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Kynurenine Pathway in Brain Tumor Pathogenesis

(2012) S. Adams et al.   CANCER RESEARCH

Genetic Ablation of Cav1 Differentially Affects Melanoma Tumor Growth and Metastasis in Mice: Role of Cav1 in Shh Heterotypic Signaling and Transendothelial Migration

(2012) F. Capozza et al.   CANCER RESEARCH

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

(2012) Ravid Straussman et al.   NATURE

Caveolin-1-Enhanced Motility and Focal Adhesion Turnover Require Tyrosine-14 but Not Accumulation to the Rear in Metastatic Cancer Cells

(2012) Hery Urra et al.   PLoS One

Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells

(2011) Shuai Zhao et al.   CANCER LETTERS

Intra-Lymph Node Prime-Boost Vaccination against Melan A and Tyrosinase for the Treatment of Metastatic Melanoma: Results of a Phase 1 Clinical Trial

(2011) A. Ribas et al.   CLINICAL CANCER RESEARCH

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk

(2011) E Arpaia et al.   ONCOGENE

Activation of the Aryl Hydrocarbon Receptor by TCDD Inhibits Mammary Tumor Metastasis in a Syngeneic Mouse Model of Breast Cancer

(2011) Tao Wang et al.   TOXICOLOGICAL SCIENCES

CAV1 Inhibits Metastatic Potential in Melanomas through Suppression of the Integrin/Src/FAK Signaling Pathway

(2010) C. Trimmer et al.   CANCER RESEARCH

Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study

(2010) Spyridon Gkalpakiotis et al.   EXPERIMENTAL DERMATOLOGY

Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population

(2010) M Fukunaga-Kalabis et al.   ONCOGENE

Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation

(2010) Perrine Pinon et al.   Pigment Cell & Melanoma Research

β-TrCP Inhibition Reduces Prostate Cancer Cell Growth via Upregulation of the Aryl Hydrocarbon Receptor

(2010) Udi Gluschnaider et al.   PLoS One

Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

(2010) Anthony E. Boitano et al.   SCIENCE

Transcriptional control of melanoma metastasis: The importance of the tumor microenvironment

(2010) Russell R. Braeuer et al.   SEMINARS IN CANCER BIOLOGY

The Aryl Hydrocarbon Receptor Functions as a Tumor Suppressor of Liver Carcinogenesis

(2009) Y. Fan et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Dioxin Receptor Deficiency Impairs Angiogenesis by a Mechanism Involving VEGF-A Depletion in the Endothelium and Transforming Growth Factor-β Overexpression in the Stroma

(2009) Angel Carlos Roman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGF 

(2009) J. M. Carvajal-Gonzalez et al.   JOURNAL OF CELL SCIENCE

The Dioxin Receptor Regulates the Constitutive Expression of the Vav3 Proto-Oncogene and Modulates Cell Shape and Adhesion

(2009) Jose M. Carvajal-Gonzalez et al.   MOLECULAR BIOLOGY OF THE CELL

Activation of the Aryl-Hydrocarbon Receptor Inhibits Invasive and Metastatic Features of Human Breast Cancer Cells and Promotes Breast Cancer Cell Differentiation

(2009) Julie M. Hall et al.   MOLECULAR ENDOCRINOLOGY

Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands

(2009) K. Kawajiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The aryl hydrocarbon receptor in immunity

(2009) Charlotte Esser et al.   TRENDS IN IMMUNOLOGY

Fitting a xenobiotic receptor into cell homeostasis: How the dioxin receptor interacts with TGFβ signaling

(2008) Aurea Gomez-Duran et al.   BIOCHEMICAL PHARMACOLOGY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE