The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk

Integrin  5 1 facilitates cancer cell invasion through enhanced contractile forces

(2011) C. T. Mierke et al.   JOURNAL OF CELL SCIENCE

Breast Cancer Cells in Three-dimensional Culture Display an Enhanced Radioresponse after Coordinate Targeting of Integrin  5 1 and Fibronectin

(2010) J.-M. Nam et al.   CANCER RESEARCH

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

ErbB2 requires integrin  5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells

(2010) K. K. Haenssen et al.   JOURNAL OF CELL SCIENCE

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

(2010) M. D. Schaller   JOURNAL OF CELL SCIENCE

Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway

(2010) Yasuhiro Kidera et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

P130Cas Src-Binding and Substrate Domains Have Distinct Roles in Sustaining Focal Adhesion Disassembly and Promoting Cell Migration

(2010) Leslie M. Meenderink et al.   PLoS One

Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion

(2009) Murat Cokakli et al.   BMC CANCER

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

(2009) Shuh Narumiya et al.   CANCER AND METASTASIS REVIEWS

Rac1 GTPase: A “Rac” of All Trades

(2009) E. E. Bosco et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Caveolin-1 tumor-promoting role in human melanoma

(2009) Federica Felicetti et al.   INTERNATIONAL JOURNAL OF CANCER

Pyk2 Inhibition of p53 as an Adaptive and Intrinsic Mechanism Facilitating Cell Proliferation and Survival

(2009) Ssang-Taek Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

The Role of Src in Solid Tumors

(2009) D. L. Wheeler et al.   ONCOLOGIST

Phosphorylation of p130Cas initiates Rac activation and membrane ruffling

(2008) Alok Sharma et al.   BMC CELL BIOLOGY

Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma

(2008) L Campbell et al.   BRITISH JOURNAL OF CANCER

The Inhibition of Tumor Cell Intravasation and Subsequent Metastasis via Regulation of In Vivo Tumor Cell Motility by the Tetraspanin CD151

(2008) Andries Zijlstra et al.   CANCER CELL

Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1

(2008) Jacky G. Goetz et al.   JOURNAL OF CELL BIOLOGY

Caveolin-1: an ambiguous partner in cell signalling and cancer

(2008) Andrew F. G. Quest et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

(2008) Ssang-Taek Lim et al.   MOLECULAR CELL

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY