Splice isoforms as therapeutic targets for colorectal cancer

Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer

(2012) Judith C. Sporn et al.   AMERICAN JOURNAL OF PATHOLOGY

Intronic microRNAs: a crossroad in gene regulation: Figure 1

(2012) Natalia Gromak   BIOCHEMICAL SOCIETY TRANSACTIONS

Gene variants in the angiogenesis pathway and prostate cancer

(2012) E. K. Amankwah et al.   CARCINOGENESIS

Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing

(2012) Glen F. Deleavey et al.   CHEMISTRY & BIOLOGY

Alternative splicing: decoding an expansive regulatory layer

(2012) Manuel Irimia et al.   CURRENT OPINION IN CELL BIOLOGY

S-1 as a core anticancer fluoropyrimidine agent

(2012) Koh Miura et al.   Expert Opinion on Drug Delivery

Beyond bevacizumab: new anti-VEGF strategies in colorectal cancer

(2012) Teresa Troiani et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Functional coupling of transcription and splicing

(2012) Marta Montes et al.   GENE

Interleukin Enhancer-binding Factor 3/NF110 Is a Target of YM155, a Suppressant of Survivin

(2012) Naoto Nakamura et al.   MOLECULAR & CELLULAR PROTEOMICS

Design principles of interconnections between chromatin and pre-mRNA splicing

(2012) Sérgio F. de Almeida et al.   TRENDS IN BIOCHEMICAL SCIENCES

Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis

(2011) Kasper Thorsen et al.   BMC GENOMICS

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Amiloride Modulates Alternative Splicing in Leukemic Cells and ResensitizesBcr-AblT315I Mutant Cells to Imatinib

(2011) Wen-Hsin Chang et al.   CANCER RESEARCH

Epigenetics in Alternative Pre-mRNA Splicing

(2011) Reini F. Luco et al.   CELL

BARD1 Expression Predicts Outcome in Colon Cancer

(2011) Judith C. Sporn et al.   CLINICAL CANCER RESEARCH

Silencing Survivin Splice Variant 2B Leads to Antitumor Activity in Taxane-Resistant Ovarian Cancer

(2011) P. E. Vivas-Mejia et al.   CLINICAL CANCER RESEARCH

Alternative Spliced Variants as Biomarkers of Colorectal Cancer

(2011) Qian Yi et al.   CURRENT DRUG METABOLISM

More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation

(2011) Reini F Luco et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

RNA structure and the mechanisms of alternative splicing

(2011) C Joel McManus et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer

(2011) Anita Sveen et al.   INTERNATIONAL JOURNAL OF CANCER

Expression and prognostic significance of survivin splice variants in diffusely infiltrating astrocytoma

(2011) Y. Huang et al.   JOURNAL OF CLINICAL PATHOLOGY

QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation

(2011) L. Novikov et al.   MOLECULAR AND CELLULAR BIOLOGY

Antisense Inhibition of Survivin Expression as a Cancer Therapeutic

(2011) R. A. Carrasco et al.   MOLECULAR CANCER THERAPEUTICS

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Antibodies in oncology

(2011) Vinochani Pillay et al.   New Biotechnology

MiniSOX9, a dominant-negative variant in colon cancer cells

(2011) R Abdel-Samad et al.   ONCOGENE

Survivin isoforms and clinicopathological characteristics in colorectal adenocarcinomas using real-time qPCR

(2011) Anastasia Pavlidou   WORLD JOURNAL OF GASTROENTEROLOGY

The survivin -31 snp in human colorectal cancer correlates with survivin splice variant expression and improved overall survival

(2011) Anna G. Antonacopoulou et al.   CELLULAR ONCOLOGY

Regulation of cyclin D1 gene expression: Figure 1

(2010) Ini-Isabée Witzel et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Genome-wide Analysis of Novel Splice Variants Induced by Topoisomerase I Poisoning Shows Preferential Occurrence in Genes Encoding Splicing Factors

(2010) S. Solier et al.   CANCER RESEARCH

Identification of ASF/SF2 as a Critical, Allele-Specific Effector of the Cyclin D1b Oncogene

(2010) N. A. Olshavsky et al.   CANCER RESEARCH

Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response

(2010) Z. Li et al.   CANCER RESEARCH

Alternative pre-mRNA splicing in digestive tract malignancy

(2010) Koh Miura et al.   CANCER SCIENCE

An Alternative Splicing Network Links Cell-Cycle Control to Apoptosis

(2010) Michael J. Moore et al.   CELL

Alternatively Spliced Products of the UGT1A Gene Interact with the Enzymatically Active Proteins to Inhibit Glucuronosyltransferase Activity In Vitro

(2010) J. Bellemare et al.   DRUG METABOLISM AND DISPOSITION

Intragenic deletions and a deep intronic mutation affecting pre-mRNA splicing in the dihydropyrimidine dehydrogenase gene as novel mechanisms causing 5-fluorouracil toxicity

(2010) André B. P. van Kuilenburg et al.   HUMAN GENETICS

Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans

(2010) Judith Bellemare et al.   JOURNAL OF PATHOLOGY

CYP24A1 splice variants—Implications for the antitumorigenic actions of 1,25-(OH)2D3 in colorectal cancer

(2010) H.C. Horváth et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Alternative Splicing of SLC39A14 in Colorectal Cancer is Regulated by the Wnt Pathway

(2010) Kasper Thorsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation

(2010) Caroline Raynal et al.   Molecular Cancer

Deciphering the splicing code

(2010) Yoseph Barash et al.   NATURE

Survivin-3B Gene Decreases the Invasion-Inhibitory Effect of Colon Cancer Cells With 5-Fluorouracil

(2010) Katsuji Sawai et al.   ONCOLOGY RESEARCH

Regulation of Alternative Splicing by Histone Modifications

(2010) R. F. Luco et al.   SCIENCE

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

VEGF121b, a new member of the VEGF xxx b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo

(2009) E S Rennel et al.   BRITISH JOURNAL OF CANCER

Alternative Splicing of the Cyclin D1 Proto-Oncogene Is Regulated by the RNA-Binding Protein Sam68

(2009) M. P. Paronetto et al.   CANCER RESEARCH

Translational strategies for development of monoclonal antibodies from discovery to the clinic

(2009) Mohammad A. Tabrizi et al.   DRUG DISCOVERY TODAY

cIAP2 as a therapeutic target in colorectal cancer and other malignancies

(2009) Koh Miura et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Therapeutic potential of manipulating VEGF splice isoforms in oncology

(2009) Emma S Rennel et al.   Future Oncology

Prognostic significance of alterations in KRAS isoforms KRAS-4A/4B andKRASmutations in colorectal carcinoma

(2009) Jehad Abubaker et al.   JOURNAL OF PATHOLOGY

ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing

(2009) Claude C. Warzecha et al.   MOLECULAR CELL

MMBGX: a method for estimating expression at the isoform level and detecting differential splicing using whole-transcript Affymetrix arrays

(2009) Ernest Turro et al.   NUCLEIC ACIDS RESEARCH

The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the Apc Min/+mouse small intestine

(2008) Charles E Patek et al.   BMC GASTROENTEROLOGY

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

(2008) D. G. Nowak et al.   JOURNAL OF CELL SCIENCE

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE