Therapeutic potential of manipulating VEGF splice isoforms in oncology

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Notch Inhibitors as a New Tool in the War on Cancer: A Pathway to Watch

(2009) Benjamin Purow   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Vascular permeability, vascular hyperpermeability and angiogenesis

(2008) Janice A. Nagy et al.   ANGIOGENESIS

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has implications for therapy

(2008) A H R Varey et al.   BRITISH JOURNAL OF CANCER

The endogenous anti-angiogenic VEGF isoform, VEGF165b inhibits human tumour growth in mice

(2008) E S Rennel et al.   BRITISH JOURNAL OF CANCER

VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis

(2008) G Thurston et al.   BRITISH JOURNAL OF CANCER

Multiple Alternative Splicing Markers for Ovarian Cancer

(2008) R. Klinck et al.   CANCER RESEARCH

Identification of Alternative Splicing Markers for Breast Cancer

(2008) J. P. Venables et al.   CANCER RESEARCH

Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

(2008) H. Kawamura et al.   CANCER RESEARCH

Failure to up-regulate VEGF165b in maternal plasma is a first trimester predictive marker for pre-eclampsia

(2008) Victoria L. Bills et al.   CLINICAL SCIENCE

Recombinant human VEGF165b protein is an effective anti-cancer agent in mice

(2008) Emma S. Rennel et al.   EUROPEAN JOURNAL OF CANCER

Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A

(2008) Jun-ichiro Yomoda et al.   GENES TO CELLS

p73 isoforms affect VEGF, VEGF165b and PEDF expression in human colorectal tumors: VEGF165b downregulation as a marker of poor prognosis

(2008) Raquel Díaz et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

(2008) D. G. Nowak et al.   JOURNAL OF CELL SCIENCE

Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1 

(2008) M. Y. Koh et al.   MOLECULAR CANCER THERAPEUTICS

The Alternatively Spliced Anti-Angiogenic Family of VEGF Isoforms VEGFxxxb in Human Kidney Development

(2008) Heather S. Bevan et al.   NEPHRON PHYSIOLOGY

Vascular endothelial growth factor in eye disease

(2008) J.S. Penn et al.   PROGRESS IN RETINAL AND EYE RESEARCH

5-Aza-2′-deoxycytidine increases the expression of anti-angiogenic vascular endothelial growth factor 189b variant in human lung microvascular endothelial cells

(2007) E. Miller-Kasprzak et al.   BIOMEDICINE & PHARMACOTHERAPY

Mammary alveolar development during lactation is inhibited by the endogenous antiangiogenic growth factor isoform, VEGF165b

(2007) Yan Qiu et al.   FASEB JOURNAL

Ordered Multi-site Phosphorylation of the Splicing Factor ASF/SF2 By SRPK1

(2007) Chen-Ting Ma et al.   JOURNAL OF MOLECULAR BIOLOGY