Article
Chemistry, Analytical
Vandana Kumari, Dinesh Kumar, Rishabh Bhardwaj, Dinesh Kumar
Summary: Ajuga parviflora is a traditionally important herb used to treat fever, diarrhoea, obesity, and diabetes. Metabolome analysis, nutritional and antioxidant activities were performed to understand its health benefits. The study identified 60 metabolites and found significant nutritional components and antioxidant activities, supporting the health benefits of Ajuga parviflora.
MICROCHEMICAL JOURNAL
(2023)
Article
Biotechnology & Applied Microbiology
Amrita Suryavanshi, Suresh Kumar, Dolly Kain, Atul Arya
Summary: The leaves of Ajuga parviflora have been traditionally used for treating hyperglycemia in the foothills of the Himalayas in India. Extracts from these leaves show inhibitory effects on carbohydrate-hydrolyzing enzymes and possess antioxidant properties. The hydroalcoholic extract exhibits higher antioxidant capacity and phenolic content compared to the hexane extract.
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2021)
Article
Plant Sciences
Jesus Pala-Paul, Lachlan M. Copeland, Joseph J. Brophy
Summary: Trachymene incisa subsp. incisa is an Australian endemic taxon with variations in leaf trichomes abundance and length. Analysis of essential oil composition shows significant differences in sesquiterpene hydrocarbons between the particularly hairy variant and the typical glabrous one, leading to identification of three different chemotypes based on main compounds.
Article
Multidisciplinary Sciences
Valtcho D. Zheljazkov, Filippo Maggi
Summary: The study showed that distillation can improve the compositional profile of cannabinoids in hemp biomass, converting cannabinoid acids into cannabinoids like CBD and CBC. Distilled hemp biomass had higher cannabinoid content compared to non-distilled, with the addition of CBN in the distilled biomass.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Miroslava Kacaniova, Nenad L. Vukovic, Natalia Cmikova, Lucia Galovicova, Marianna Schwarzova, Veronika Simora, Przemyslaw Lukasz Kowalczewski, Maciej Ireneusz Kluz, Czeslaw Puchalski, Ladislav Bakay, Milena D. Vukic
Summary: This study analyzed the chemical composition and various properties of Salvia sclarea essential oil (SSEO). The results showed that SSEO has moderate antimicrobial and antibiofilm activities, as well as insecticidal potential. The study also identified the main constituents of SSEO and their antioxidant activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Robert A. DiSilvestro, Susan Olivo Marston, Autumn Zimmerman, Elizabeth Joseph, Carolynn Boeh McCarty
Summary: Research suggests that GLA may affect resting metabolic rate and help with weight control. However, in overweight young adults with a family history of obesity, borage oil did not affect resting metabolic rate but could improve blood lipid measures.
Article
Agronomy
Emel Karaca Oner, Arslan Uzun
Summary: This research aimed to investigate the parameters of seedling growth, yield, and essential oil components in lemon balm populations from several provinces in Turkey. The results showed significant variations in plant height, yield, and essential oil ratio among different regions.
EMIRATES JOURNAL OF FOOD AND AGRICULTURE
(2023)
Article
Agronomy
Mayara Ketllyn de Paula Rosetti, Dejane Santos Alves, Isabela Caroline Luft, Katiane Pompermayer, Andressa Soares Scolari, Gabriela Trindade Silva, Murilo Silva de Oliveira, Javier Andres Garcia Vanegas, Horacio Bambo Pacule, Geraldo Humberto Silva, Denilson Ferreira de Oliveira, Geraldo Andrade Carvalho
Summary: This study evaluated the toxicity of essential oils from plants of the Annona neolaurifolia, Duguetia lanceolata, and Xylopia brasiliensis species on the fall armyworm (FAW) and its natural enemy, Trichogramma pretiosum. The essential oils from the leaves and stem bark of Duguetia lanceolata were the most effective against FAW, and they contained beta-caryophyllene and caryophyllene oxide as major compounds that reduced the insect's survival probability. Additionally, the essential oil from Duguetia lanceolata leaves showed low toxicity to the egg-larva stage of Trichogramma pretiosum, suggesting its potential for controlling FAW.
Article
Agricultural Engineering
Ylenia Pieracci, Flavia Fulvio, Valeria Isca, Luisa Pistelli, Laura Bassolino, Massimo Montanari, Anna Moschella, Guido Flamini, Roberta Paris
Summary: The inflorescences of Cannabis sativa L. are a valuable by-product of industrial hemp cultivation, and the volatile fraction of these inflorescences has attracted attention for its applications in various fields. This study investigated the effect of phenological stage on the chemical composition and hydro-distillation yield of hemp-derived essential oil (EO). Two hemp varieties, Codimono (monoecious) and Fibrante (dioecious), were cultivated, and the flowering tops were collected at different stages. Analysis of the EO revealed that terpenes and phyto-cannabinoids were the major chemical classes, with sesquiterpene hydrocarbons being the most abundant components. The EO yield increased with phenological development, reaching its highest rate at seed harvest time.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Feride Akman, Azize Demirpolat, Aleksandr S. Kazachenko, Anna S. Kazachenko, Noureddine Issaoui, Omar Al-Dossary
Summary: In this study, theoretical calculations were performed to investigate the interactions between the main components of Phlomis bruguieri Desf. essential oil and water. The molecules caryophyllene oxide, beta-pinene, 1,8-cineol, a-cubebene, and b-caryophyllene, which have the highest contents in the essential oil, were selected for the calculations. The results provide important insights into the properties of oil-water mixtures, which are important in biology and industry.
Article
Agricultural Engineering
Shubham Srivastava, R. K. Lal, V. R. Singh, P. K. Rout, R. C. Padalia, Anju Kumari Yadav, Laldingngheti Bawitlung, Divya Bhatt, Anil K. Maurya, A. Pal, D. U. Bawankule, Anand Mishra, P. Gupta, C. S. Chanotiya
Summary: Pogostemon cablin (Blanco) Benth. plant is known for its high essential oil production, and a new variety has been developed for cultivation in India. The patchouli essential oil exhibits significant anti-inflammatory and antimicrobial activities. Various sesquiterpenoids with these activities have been identified. In addition, a new method for authenticating patchouli essential oils has been reported.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Plant Sciences
Jorge M. M. Alves-Silva, Emma Cocco, Alessandra Piras, Maria Jose Goncalves, Ana Silva, Danilo Falconieri, Silvia Porcedda, Maria Teresa Cruz, Andrea Maxia, Ligia Salgueiro
Summary: This study aims to uncover the chemical composition and properties of the essential oil from Salvia cacaliifolia Benth. It was found that the essential oil has antifungal and anti-inflammatory effects, as well as the ability to promote wound healing and prevent aging. These findings highlight the potential of Salvia cacaliifolia essential oil for the development of sustainable and environmentally friendly skin products.
Article
Chemistry, Medicinal
Godfried Dougnon, Michiho Ito
Summary: The study found that Chromolaena odorata essential oil has sedative activity in mice, with caryophyllene oxide identified as the key compound responsible for this effect. Caryophyllene oxide showed potent CNS depressant effects and effectively reduced locomotor activity in mice. Interestingly, the precursor beta-caryophyllene also exhibited sedative activity, highlighting the potential of sesquiterpene compounds for managing sleep and CNS-related disorders.
Article
Plant Sciences
Valquiria Bruna Guimaraes Silva, Beatriz Meyruze Barros da Fonseca, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Daniela Maria do Amaral Ferraz Navarro, Alisson Macario de Oliveira, Thiago Henrique Napolea, Maria Tereza dos Santos Correia, Vera Lucia de Menezes Lima, Wendeo Kennedy Costa, Marcia Vanusa da Silva
Summary: The aim of this study was to evaluate the antinociceptive and anti-inflammatory potential of Psidium cattleyanum leaves essential oil. Gas chromatography-mass spectrometry (GC/MS) was used to analyze the oil. The results showed that the essential oil has significant antinociceptive and anti-inflammatory effects, and has potential for application in the pharmaceutical and food industry.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Immunology
Andreza Larissa do Nascimento, Joyce Bezerra Guedes, Wendeo Kennedy Costa, Bruno Oliveira de Veras, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Daniela Maria do Amaral Ferraz Navarro, Maria Tereza dos Santos Correia, Thiago Henrique Napoleao, Alisson Macario de Oliveira, Marcia Vanusa da Silva
Summary: This study is the first to identify the components of Eugenia pohliana essential oil and evaluate its antinociceptive and anti-inflammatory activities. The major components of the oil are (E)-beta-caryophyllene, delta-cadinene, and alpha-cadinol. The results showed that the essential oil has significant antinociceptive and anti-inflammatory effects, acting through the activation of opioid receptors.
INFLAMMOPHARMACOLOGY
(2022)
Article
Chemistry, Organic
Akash Ved, Hweta Gupta, Namrata Singh, Karuna S. Shukla, Om Prakash, Neeru Gaur
Summary: Operculina turpethum roots have been studied for their physicochemical properties, phytochemical compounds, and therapeutic potential for treating inflammation. The main active component identified was beta-sitosterol.
LETTERS IN ORGANIC CHEMISTRY
(2022)
Review
Endocrinology & Metabolism
Nadeem Rais, Rizwan Ahmad, Akash Ved, Kehkashan Parveen, Darakhshan Gazala Bari, Om Prakash
Summary: Diabetes mellitus and steroid medication, coincided with COVID-19, weaken the immune system and increase the risk of opportunistic infections such as mucormycosis. High blood sugar and decreased insulin levels in DKA patients can lead to the development of mucormycosis. Managing hyperglycemia is crucial in the treatment of mucormycosis in DKA patients.
CURRENT DIABETES REVIEWS
(2023)
Review
Chemistry, Medicinal
Sonu Kumar Mahawer, Ravendra Kumar, Om Prakash, Sushila Arya, Shailja Singh, Mozaniel Santana de Oliveira, Dharmendra Singh Rawat
Summary: Medicinal and aromatic plants have been used in ethnopharmacology since ancient times and continue to be of interest to researchers for developing plant-based medicines. Zingiberaceae is a well-known plant family, and Zingiber roseum is a medicinal and aromatic species in this family. It has a wide range of medicinal properties and bioactive compounds such as terpenes and terpenoids, phenols, flavonoids, alkaloids, saponins, ascorbic acid, and unique constituents like zerumbone. This review discusses the botanical descriptions, phytochemistry, ethnopharmacological uses, and medicinal properties of Z. roseum as reported by researchers.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Pringal Upadhyay, Sonu Kumar Mahawer, Ravendra Kumar, Om Prakash, Himani Karakoti, Tanuja Kabdal, Dharamendra Singh Rawat
Summary: In this study, the chemical composition and biological activities of essential oils from five Strobilanthes species were investigated. The essential oils showed significant antioxidant, anti-inflammatory, and antidiabetic activities. This suggests that the essential oils from these Strobilanthes species can be used as ecofriendly antioxidants, anti-inflammatory agents, and antidiabetic agents.
BIOCHEMICAL SYSTEMATICS AND ECOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Akanksha Malhotra, Avneesh Rawat, Om Prakash, Ravendra Kumar, R. M. Srivastava, Satya Kumar
Summary: This study investigated the variation of essential oil composition from Artemisia annua L. aerial parts harvested in rainy and winter seasons. The GC-MS analysis identified different major constituents between the two essential oils. Both oils showed antifeedant and nematocidal activities. In silico tests revealed that the major components had good docking scores with acetylcholinesterase compared to carbofuran.
BIOCHEMICAL SYSTEMATICS AND ECOLOGY
(2023)
Article
Plant Sciences
Kirti Nagarkoti, Om Prakash, Avneesh Rawat, Chenesh Patel, Ravendra Kumar, R. M. Srivastava, Satya Kumar, D. S. Rawat
Summary: Micromeria biflora Benth. is an important medicinal herb used for treating various ailments. The essential oil of Micromeria biflora exhibited insecticidal, antimicrobial, and antioxidant activities.
JOURNAL OF ESSENTIAL OIL BEARING PLANTS
(2023)
Article
Food Science & Technology
Sushila Arya, Sonu Kumar Mahawer, Himani Karakoti, Ravendra Kumar, Om Prakash, Satya Kumar, Mamta Latwal, Ganesh Panday, Ravi Mohan Srivastava, Mozaniel Santana de Oliveira, Dharmendra Singh Rawat
Summary: The current study aimed to evaluate the altitudinal variability in chemical compounds, nematicidal, insecticidal, herbicidal, and antifungal activity of the essential oils of H. coronarium collected from different habitats in Uttarakhand. The major compounds identified through GC-MS analysis included 1, 8-cineole, coronarin E, alpha-terpineol, terpinen-4-ol, alpha-pinene, Z-caryophyllene, and linalool. Heat map clustering, Venn diagram, and principal component analysis (PCA) were performed to observe the variation in oil composition. The essential oils showed significant nematicidal, insecticidal, herbicidal, and antifungal activity against tested organisms.
JOURNAL OF FOOD QUALITY
(2023)
Article
Plant Sciences
Soni Chauhan, Touseef Fatima, Amita Dubey, Puneet Singh Chauhan, Om Prakash, Poonam C. Singh
Summary: The aim of this study was to investigate the persistence of pesticides in different soil conditions and their effects on soil microbial diversity. The researchers conducted experiments in pots under net house conditions and used Biolog to analyze substrate utilization patterns. HPLC analysis was used to study the persistence of carbendazim in fallow soil, maize rhizosphere, and plant parts with and without Trichoderma. The results showed that fallow conditions increased the persistence of carbendazim in soil and affected the soil microbial community, while the application of Trichoderma enhanced its degradation.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2023)
Review
Pharmacology & Pharmacy
Akib Nisar, Suresh Jagtap, Suresh Vyavahare, Manasi Deshpande, Abhay Harsulkar, Prabhakar Ranjekar, Om Prakash
Summary: Advances in biomedical research have revealed that inflammation and its associated diseases pose the biggest threat to public health. While inflammation is a natural response of the body to external stimuli, prolonged activation of detrimental pathways can lead to chronic low-grade inflammation, which is linked to various degenerative disorders and chronic health issues. Current anti-inflammatory drugs often have undesirable side effects, necessitating the development of drugs that target chronic inflammation with fewer side effects. Medicinal plants contain bioactive compounds that possess potent anti-inflammatory properties and can regulate molecular mechanisms to alleviate inflammation-associated diseases. This review focuses on the anti-inflammatory properties of these phytochemicals and their mechanisms of action, with an emphasis on those that have been evaluated in preclinical and clinical studies. The review also discusses recent trends and gaps in the development of phytochemical-based anti-inflammatory drugs.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Vijay Kumar Juyal, Shweta Chand Thakuri, Mohit Panwar, Om Prakash, Viveka Nand
Summary: A bidentate hydroxy alpha-aminophosphonates ligand and its Mn(II), Fe(III), and Zn(II) metal complexes were prepared and characterized by various methods. Thermal analysis revealed the thermal decomposition behavior of the metal complexes. The antibacterial and antioxidant activities of the compounds were tested, and molecular docking studies showed good interaction with the target protein.
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Avneesh Rawat, Om Prakash, Ravendra Kumar, A. K. Verma, Satya Kumar, Kirti Nagarkoti, R. M. Srivastava
Summary: A chemical study on the rhizomes of Hedychium spicatum led to the discovery of labdane diterpenes, hedychilactone A and B. The chemical structures of these compounds were determined through spectral data analysis and comparison with literature data. The compounds were evaluated for their pesticidal activities and their bioactivity was predicted using computational studies. These compounds show potential as natural pesticidal agents and further research is needed to understand their mechanisms and conduct field trials.
ANALYTICAL CHEMISTRY LETTERS
(2023)
Article
Multidisciplinary Sciences
Avneesh Rawat, Om Prakash, Kirti Nagarkoti, Ravendra Kumar, Ashok K. Verma, Satya Kumar, Ravi M. Srivastava, Mamta Latwal, Ganesh Pandey
Summary: The study identified the active constituents in the chloroform extract of H. spicatum rhizomes (HS-RCLE) and validated its in-vitro pesticidal activities using molecular docking techniques. GC/MS analysis revealed 14 compounds, contributing to 84.1% of the total composition, with oxygenated sesquiterpenes as the dominant compounds. The extract showed significant inhibition of egg hatchability, immobility of Meloidogyne incognita, insecticidal activity on Spodoptera litura, phytotoxic activity on Raphanus raphanistrum seeds, and anti-fungal activity on Curvularia lunata.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2023)
Article
Pharmacology & Pharmacy
Sonali Sethi, Om Prakash, Ravendra Kumar, Shiv Kumar Dubey, Mamta Arya, Anil Kumar Pant
Summary: This study investigates the chemical composition, phytochemicals, antifungal activities, antioxidant assays, and total phenolic content of essential oil and various solvent extracts from the flowers of Alpinia malaccensis (Burm.f.). The findings suggest that Alpinia malaccensis flowers have good antioxidant potential and fungicidal activity, making them a promising candidate for the development of natural food preservatives.
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Saumya Khare, Rajesh Kumar Singh, Om Prakash
Summary: Green synthesis of silver nanoparticles with higher stability and biocompatibility has gained wide interest in biomedical applications. In this study, silver nanoparticles were synthesized using radish seeds as reducing and stabilizing agents, and characterized using various techniques. The synthesized nanoparticles exhibited crystalline nature, spherical shape, and small size. The FTIR spectra confirmed the reduction of silver ions by biomolecules in the seed extract. Hemolysis assay and cell viability assay demonstrated the non-toxic nature and cell compatibility of the silver nanoparticles. These preliminary studies suggest the biocompatible properties of silver nanoparticles, which are essential for their potential use as drug-carrier systems in future cancer therapy.
RESULTS IN CHEMISTRY
(2022)
Article
Pharmacology & Pharmacy
Rajesh Kumar, Shazia Usmani, Mehnaz Kamal, Brijesh Singh, Om Prakash, Shadma Wahab, Mohammad Fahad Ullah
Summary: Lata Kranja, a member of the Caesalpiniaceae family, has been widely used in ethnomedicinal practices. However, there is a lack of reverse pharmacognostic research on its therapeutic effect. This study found that the methanolic extract of C. crista exhibits good antioxidant activity and inhibits cell proliferation. These findings suggest the need for further exploration of the therapeutic potential of this plant.
LATIN AMERICAN JOURNAL OF PHARMACY
(2022)
