Journal
CARBOHYDRATE RESEARCH
Volume 344, Issue 12, Pages 1391-1396Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2009.04.028
Keywords
N-Glycan; Paucimannose; Caenorhabditis elegans; Drosophila melanogaster; Biosynthesis; Longevity
Funding
- Canadian Institutes of Health Research (CIHR)
Ask authors/readers for more resources
There is a rich diversity of paucimannose N-glycans in worms and flies, and these may play a role in the survival of these organisms. Although paucimannose N-glycans are not expressed in vertebrates, complex N-glycans may take over some of the functions of paucimannose N-glycans. Identification of the target proteins of beta-1,2-N-acetylglucosaminyltransferase I (GnTI) in worms and flies and elucidation of their functions may thus lead to a better understanding of the role of GnTI-dependent glycoproteins in the survival/longevity of both invertebrates and vertebrates. (C) 2009 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available