Article
Polymer Science
Yoshitomo Furushima, Christoph Schick, Akihiko Toda, Hideaki Takahashi, Toshiumi Tatsuki, Satoshi Fujiwara, Kazuma Okada, Masatoshi Ohkura
Summary: Fast scanning calorimetric experiments were conducted to investigate the effect of pre-nucleation on the crystallization and melting kinetics of low-isotacticity polypropylene (LT-PP). The presence of crystal nuclei accelerated the isothermal crystallization rate of LT-PP, but had no effect on the melting kinetics of secondary crystallized LT-PP. Moreover, increasing amounts of crystal nuclei resulted in a decrease in the maximum primary crystallization, which can be attributed to the formation of uncrystallizable defects between the crystalline domains.
Article
Materials Science, Ceramics
Semen E. Lapuk, Marat A. Ziganshin, Radik A. Larionov, Timur A. Mukhametzyanov, Christoph Schick, Alexander V. Gerasimov
Summary: Robust determination of parameters governing the stability of amorphous drugs is crucial in modern pharmaceutics. The kinetic stability of these systems greatly impacts their practical applications. This study determined the critical cooling rates and kinetic parameters of cold crystallization for four slowly crystallizing sulfonamides. The Nakamura crystallization model demonstrated good prognostic ability by determining the stability time profile of drug systems prone to crystallization from non-isothermal thermokinetic data.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Chemistry, Physical
Iosif Sorin Fazakas-Anca, Arina Modrea, Sorin Vlase
Summary: This paper describes an improved method for calculating reactivity ratios using the neuronal networks optimization algorithm, gradient descent. The new calculation method shows better results compared to existing methods when evaluating reactivity ratios at different levels of conversion.
Article
Polymer Science
Akihiko Toda
Summary: The crystallization kinetics of poly(butylene terephthalate) under high supercooling was investigated using Temperature-Modulated Fast Scanning Calorimetry (TM-FSC). The study found a temperature dependence of crystal growth rate and compared it with the peak time of heat flow during isothermal crystallization. The crystal growth rate was found to be practically determined by a mobility factor near the glass transition.
Article
Chemistry, Physical
D. V. Louzguine-Luzgin, Yu. P. Ivanov, A. L. Greer
Summary: The crystallization behavior of a Cu58Y37Sc5 metallic glassy alloy was investigated using various methods. Differential scanning and isothermal calorimetries were performed to study the phase transformations. X-ray diffractometry studies showed the simultaneous formation of Cu2Y, CuY, and CuSc crystalline phases, indicating eutectic crystallization, while the isothermal crystallization kinetics corresponded to primary crystallization. Transmission electron microscopy observations revealed a complex crystallization process involving heterogeneous nucleation on pre-existing particles.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Polymer Science
Li Qian, Yaxian Wang, Ying Lu, Yongfeng Men
Summary: Research on the crystallization behaviors of two impact copolymer polypropylenes (ICP) revealed differences in their crystallization peaks at different cooling rates, with ICP-A and ICP-B showing distinct behaviors. These differences can be attributed to their different chain microstructures.
Article
Polymer Science
Janetty Jany Pereira Barros, Carlos Pereira Soares, Esperidiana Augusta Barretos de Moura, Renate Maria Ramos Wellen
Summary: This study investigates the effect of gamma radiation on the interaction between kraft lignin and PBAT/PLA blend. The results show that irradiation promotes the miscibility and compatibility of PBAT/PLA/lignin. The crystallization peak of PBAT/PLA/lignin shifts to lower temperatures and the crystallization rate decreases after irradiation.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Valentina Pirela, Justine Elgoyhen, Radmila Tomovska, Jaime Martin, Cuong Minh Quoc Le, Abraham Chemtob, Brahim Bessif, Barbara Heck, Guenter Reiter, Alejandro J. Mueller
Summary: A complex crystallization behavior was observed for the alternating copolymer DMDS-alt-DVE synthesized via thiol-ene step-growth polymerization. Understanding the underlying complex crystallization processes of such innovative polythioethers is critical for their application, for example, in polymer coating technologies. The study of polymorphism, crystallization, and morphological differences can have significant implications on mechanical resistance and barrier properties of these polymers.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Applied
Ivano Maule, Gabriele Razzetti, Alessandro Restelli, Alessandro Palmieri, Cinzia Colombo, Roberto Ballini
Summary: The thermal stability of a set of aliphatic nitroalkanes was tested by DSC analysis, showing similar exothermic decomposition phenomenon for all compounds. Recommendations for avoiding decomposition were provided based on the estimated maximum process temperature.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2021)
Article
Chemistry, Multidisciplinary
R. J. Sengwa, Priyanka Dhatarwal
Summary: This study prepared different compositional ratio organic polymer blend matrices and hybrid polymer nanocomposites with dispersed inorganic montmorillonite nanoclay. The structures and properties of these materials were characterized using advanced techniques. The results showed that the properties of these nanocomposites were influenced by the composition ratio and nanofiller concentration. These materials exhibited both tunable dielectric and optical properties, making them promising for applications in polymer-based device technologies.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2022)
Article
Environmental Sciences
Mauricio Rodriguez Chialanza, Sofia Favre Samarra, Andres Perez Parada
Summary: The study found that the size of microplastic particles affects the DSC signal, but through appropriate sample preparation, signals corresponding to microplastics of different sizes can be identified and quantified. Additionally, the application of DSC technique in the field of microplastics may provide estimates of the number of microplastic particles within a sample.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Polymer Science
Poovathungal Abdulrahman Jeemol, Suresh Mathew, Chethrappilly Padmanabhan Reghunadhan Nair
Summary: The free radical copolymerization of nadic anhydride and styrene was investigated for the first time, revealing a good copolymerizability between the two monomers. Based on the reactivity ratio, the probability for formation of sequences of nadic anhydride in its copolymer with styrene was computed for a few compositions.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2021)
Article
Polymer Science
Dario Heidrich, Michael Gehde
Summary: According to the study, the structural composition of both PBT and PET is mainly characterized by a large fraction of the rigid amorphous phase. The rigid amorphous phase is mainly formed during the primary or secondary crystallization processes at different temperature ranges.
Article
Polymer Science
Mingjin Liu, Jin Chen, Jiaxu Luo, Jie Min, Qiang Fu, Jie Zhang
Summary: Shear mode plays a crucial role in disentangling molecular chains, with ramping-up shear having the most efficient influence. This results in a higher molecular weight between entanglements and much lower entanglement density, enabling higher chain mobility and greatly enhancing crystallization kinetics.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Materials Science, Ceramics
Hongwei Guo, Shouyi Guo, Yibo Gao, Lei Liu, Longxing Chi, Yun Bai, Relva C. Buchanan, Yuxuan Gong
Summary: Glass has excellent friction, lubricating properties, and thermal stability, making it widely used in mechanical processing and other applications. This study analyzed the nucleation and crystal growth kinetics of SBBC system glasses and determined their crystallization kinetic parameters. The effects of time, temperature, and crystal phase on the crystallization rate curves were established. The crystal precipitation process of SBBC system glasses was verified through SEM images, and the negative effect of early crystallization on lubricating properties was observed.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Polymer Science
Duarte M. Cecilio, Maria L. Cerrada, Ernesto Perez, Auguste Fernandes, Joao Paulo Lourenco, Timothy F. L. McKenna, M. Rosario Ribeiro
Summary: A novel supported activator (SA) approach utilizing nano-sized supported methylaluminoxane (MAO)-activator based on halloysite natural nanotubes (HNT) and an in situ supporting concept is developed for the preparation of high density polyethylene (HDPE)-based highly performant hybrid materials. The SA method shows enhanced polymerization activities and generates ultimate materials with improved morphological features, greater crystallinity, thicker crystals, and significantly increased stiffness. The use of high aspect ratio support like HNT also contributes to better mechanical properties compared to similar HDPE hybrid materials derived from dendrimer-like silica (DS) nanospheres.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
A. Chiloeches, R. Fernandez-Garcia, M. Fernandez-Garcia, A. Mariano, I Bigioni, A. Scotto d'Abusco, C. Echeverria, A. Munoz-Bonilla
Summary: In this study, antimicrobial fibers based on biodegradable polymers, poly(lactic acid) (PLA), and poly(butylene adipate-co-terephthalate) (PBAT) were prepared by electrospinning. A biodegradable/bio-based polyitaconate containing azoles groups (PTTI) was incorporated into the electrospinning formulations at 10 wt.%. The resulting fibers were functionalized with cationic azolium groups through N-alkylation for antibacterial activity. The efficacy of the fibers against bacteria was evaluated, showing a 4-Log reduction against S. aureus and 1.7-Log reduction against MRSA for quaternized PLA/PTTI fibers. The biocompatibility and bioactivity of the fibers were also assessed, indicating no cytotoxic effect but a cytostatic effect attributed to electrostatic interactions.
MACROMOLECULAR BIOSCIENCE
(2023)
Article
Polymer Science
Enrique Blazquez-Blazquez, Rosa Barranco-Garcia, Tamara M. Diez-Rodriguez, Maria L. Cerrada, Ernesto Perez
Summary: Different materials based on an L-rich polylactide (PLA) matrix, acetyl tri-n-butyl citrate (ATBC) plasticizer, and mesoporous MCM-41 particles as nucleating agent were obtained by melt extrusion. The incorporation of plasticizer and nucleating particles reduced the phase transition temperature of PLA and promoted its crystallization. A significant increase in PLA crystallization rate was observed due to the synergistic effect of ATBC and MCM-41.
Article
Chemistry, Physical
Zeineb Chorfi, Djouhra Aggoun, Selma Houchi, Zakia Messasma, Mostafa S. Abd El-Maksoud, Marta Fernandez-Garcia, Daniel Lopez, Chawki Bensouici, Ali Ourari, Yasmina Ouennoughi
Summary: The Ni(II) complex was successfully synthesized and characterized using various techniques such as elemental analysis, spectroscopic studies, thermal analysis, X-ray powder diffraction, and morphological measurements. The redox properties of the complex were investigated using cyclic voltammetry, and the structure was determined using density functional theory calculations. The complex exhibited a strong tyrosinase inhibitory activity in vitro.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Biochemistry & Molecular Biology
Rosa Barranco-Garcia, Alberto Garcia-Penas, Enrique Blazquez-Blazquez, Jorge A. Ressia, Lidia M. Quinzani, Enrique M. Valles, Jose M. Gomez-Elvira, Ernesto Perez, Maria L. Cerrada
Summary: In this study, nanocomposites based on polypropylene are synthesized by in situ polymerization with the presence of mesoporous SBA-15 silica. The incorporation of polypropylene into the silica structure is confirmed by thermal analysis, and the addition of silica has a significant effect on the rheological properties of the materials.
Article
Chemistry, Physical
Pilar Posadas, Juan L. Valentin, Rosario Benavente, Enrique Blazquez-Blazquez, Ane Urtiaga, Juan A. Alvarez, Maria L. Cerrada
Summary: The effect of electron beam (EB) irradiation on low and high density polyethylenes (LDPE and HDPE) at different doses is analyzed. Important parameters such as degree of crystallinity, melting or crystallization temperatures are dependent on the initial PE molecular architecture, which also controls the gel content and the dose of EB applied. The molecular changes during EB irradiation lead to hindrance in crystallization capacity, reduction in crystallinity, and formation of thinner crystallites in both LDPE and HDPE.
RADIATION PHYSICS AND CHEMISTRY
(2023)
Article
Polymer Science
Maria L. Cerrada, Javier Arranz-Andres, Alicia Caballero-Gonzalez, Enrique Blazquez-Blazquez, Ernesto Perez
Summary: Different amounts of CNT have been incorporated in PVDF-based nanocomposites by solvent blending and precipitation, followed by compression molding. The inclusion of CNT promotes the formation of polar β phase in PVDF, resulting in the coexistence of α and β lattices. CNT acts as a nucleating agent and reinforcement, increasing the stiffness and conductivity of the nanocomposites.
Article
Polymer Science
Maria Dolores Martin-Alonso, Valentina Salaris, Adrian Leones, Victor Hevilla, Alexandra Munoz-Bonilla, Coro Echeverria, Marta Fernandez-Garcia, Laura Peponi, Daniel Lopez
Summary: Functionalized silver nanoparticles were successfully incorporated into PLA solutions to produce multifunctional polymeric fibers using centrifugal force-spinning. The effects of nanoparticle incorporation and fiber preparation method on morphology, thermomechanical properties, biodisintegration, and antimicrobial behavior were investigated. The results showed that the best thermomechanical behavior was achieved with 1 wt% of nanoparticles, and the fibers exhibited antibacterial activity with a killing percentage between 65 and 90%. All samples were disintegrable under composting conditions. Additionally, a good thermally activated shape-memory effect was observed in fiber mats with 2 wt% of nanoparticles.
Article
Polymer Science
Tamara M. Diez-Rodriguez, Enrique Blazquez-Blazquez, Marta Fernandez-Garcia, Alexandra Munoz-Bonilla, Ernesto Perez, Maria L. Cerrada
Summary: Composites based on PLLA and MCM-41, either neat or modified with Ag, are prepared and show antimicrobial properties. The thermal stability, nucleation efficiency, and mechanical response of PLLA are influenced by MCM-41 nature and content. WAXS measurements reveal the formation of ordered ff crystals in the composites containing MCM-41@Ag. The composites with higher silica content exhibit higher MH values and remarkable antimicrobial features.
Article
Polymer Science
Victor Hevilla, Agueda Sonseca, Coro Echeverria, Alexandra Munoz-Bonilla, Marta Fernandez-Garcia
Summary: In this study, the formation of polymeric networks with potential antimicrobial character was described. The networks were based on an acrylate oligomer, poly(mannitol sebacate) (PMS), and an enzymatically synthesized methacrylic monomer with thiazole groups (MTA). Physicochemical characterization revealed that the incorporation of MTA into the networks and subsequent quaternization affected their mechanical behavior and surface wettability. The introduction of permanent cationic charges in the network surface gave antimicrobial activity to them, as confirmed by the analysis against Gram-positive and Gram-negative bacteria and red blood cells for antibacterial behavior and hemotoxicity, respectively.
Article
Materials Science, Multidisciplinary
Pedro Canamero, Marta Fernandez-Garcia, Jose Luis de la Fuente
Summary: In this study, the adhesion properties of poly(GMA-co-BA) copolymers were investigated on different metal surfaces using three different curing agents. The optimal curing conditions were determined using DSC analysis, and the adhesion performance was evaluated through single-lap shear tests. The results showed that the choice of curing agent influenced the adhesion strength and the optimal curing temperature, with the best performance observed using 2-CA as the curing agent with aluminum and iron substrates.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Materials Science, Characterization & Testing
Sergio Fernandez-Delgado, Alberto Garcia-Penas, Daniel Serrano, Maria L. Cerrada, Jose M. Gomez-Elvira
Summary: Polypropylene-based thermoplastic elastomers are highly sought-after materials in the industry due to their excellent mechanical performance and durability. They play a crucial role in the automotive sector, accounting for up to 32% of the total plastic used in cars. In this study, poly(propylene-co-ethylene-co-norbornene) terpolymers were investigated as potential candidates for a new class of thermoplastic elastomers with tunable properties. However, their thorough characterization has been hindered by the complexity of their 13CNMR spectra. The researchers successfully synthesized and characterized these terpolymers using NMR analysis, providing insights into their microstructure and composition.
Article
Polymer Science
Victor Hevilla, Agueda Sonseca, Marta Fernandez-Garcia
Summary: In this study, one-pot enzymatic synthesis procedures were developed to obtain poly(glycerol adipate) macromers with methacrylate end-functional groups. The obtained macromers showed a high fraction of methacrylate end groups and could be crosslinked under UV irradiation in a simple one-step procedure. This research provides a new approach to obtain methacrylate-functional linear macromers without the need for complex acrylation/methacrylation procedures.
Article
Nanoscience & Nanotechnology
Alberto Chiloeches, Jakub Zagora, Daniela Placha, Marcelo D. T. Torres, Cesar de la Fuente-Nunez, Fatima Lopez-Fabal, Yolanda Gil-Romero, Raquel Fernandez-Garcia, Marta Fernandez-Garcia, Coro Echeverria, Alexandra Munoz-Bonilla
Summary: This study investigated the synergistic antimicrobial effect of a cationic biobased polymer and the antimicrobial peptide temporin L. The results showed that the covalently conjugated polymer-peptide displayed an antagonistic effect, but incorporating both antimicrobial compounds into fibers improved antibacterial performance.
ACS APPLIED BIO MATERIALS
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
