Article
Engineering, Environmental
Xiaodong Chen, Danfeng Wang, Shuang Wang, Hongying Song, Qiang Gu, Yumin Zhang
Summary: A novel amphoteric CMC-g-PDMC flocculant was synthesized via graft copolymerization, with optimal conditions determined through orthogonal experiments. Characterization of the structure and properties revealed that CMC-g-PDMC has good dewatering capabilities for municipal sludge.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Chemistry, Applied
Jingshu Cui, Xiaojun Niu, Dongqing Zhang, Jinling Ma, Xifen Zhu, Xiaoxian Zheng, Zhang Lin, Mingli Fu
Summary: A novel flocculation strategy using chitosan-amphoteric starch (C-A) dual flocculants was proposed for simultaneously removing Microcystis aeruginosa and algal organic matter (AOM), providing new insights for harmful algal bloom control in an efficient, cost-effective and ecologically friendly way.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Applied
Yuyue Zhong, Yu Tian, Xingxun Liu, Li Ding, Jacob Judas Kain Kirkensgaard, Kim Hebelstrup, Jean-Luc Putaux, Andreas Blennow
Summary: The study showed that microwave treatment has different effects on the structure and properties of pure granular amylose (AM) and pure granular amylopectin (AP) starches. The crystallinity of AM starch initially increased then decreased, while that of AP starch decreased and then increased. Prolonged treatment of AM granules significantly increased resistant starch and water solubility.
FOOD HYDROCOLLOIDS
(2021)
Article
Biotechnology & Applied Microbiology
Quan Wang, Kazuyuki Oshita, Masaki Takaoka
Summary: The study found that AlCl3 had wide application for both freshwater and marine microalgae, chitosan was effective for freshwater species, and ACPAM was valid for three freshwater species. In contrast, NaOH could only flocculate marine microalgae and had longer settling times.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2021)
Article
Engineering, Chemical
Yuyang Wu, Junyi Jiang, Qiang Sun, Yanyan An, Rui Zhao, Huaili Zheng, Hong Li
Summary: Surface charges of the suspended colloidal particles in water can be either positive or negative. A series of amphoteric starch-based flocculants were successfully synthesized and used for the removal of contaminants with different charges from water. The results showed that these eco-friendly flocculants exhibited high flocculation performance for both kaolin and hematite suspensions.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Food Science & Technology
Xiangxiang Sun, Ahmed S. M. Saleh, Zhuangzhuang Sun, Xiangzhen Ge, Huishan Shen, Qian Zhang, Xiuzhu Yu, Li Yuan, Wenhao Li
Summary: The study demonstrated that dual modification of rice starch using combined MW and CP treatments significantly altered the starch's crystallinity, swelling power, and viscosity compared to single treatments. However, the treatments had minimal impact on the starch's crystalline structure and molecular weight. The dual treatment resulted in a higher content of resistant starch, showcasing the potential for industrial applications.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Chemical
Stepheney Davey, Joao B. P. Soares
Summary: The article discusses the synthesis and characterization of amylopectin-graft-hydrolyzed-poly(methyl acrylate) copolymers for treating oil sands tailings. The flocculation and dewatering results are strongly influenced by the combination of hydrophobic amylopectin backbones with hydrophilic hydrolyzed poly(methyl acrylate) grafts. These hybrid polymers show promise as an attractive alternative for treating oil sands and potentially other mineral ore tailings.
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Chemistry, Physical
Ashkan Bahadoran, Qinglei Liu, Saeid Masudy-Panah, Jeffrey Roshan De Lile, Seeram Ramakrishna, Ali Fakhri, Vinod Kumar Gupta
Summary: Ag-doped CoTiO3 (Ag-CTO) and Ag-doped CoTiO3/Chitosan-amylopectin (Ag-CTO/CSAP) were prepared using hydrothermal method for photocatalysis, showing a reduction in band-gap energy of Ag-CTO/CSAP nanocomposites and the highest catalytic activity for dye degradation. The nanocomposites have substantial bactericidal and fungicidal properties against specific microorganisms.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Applied
Yunyun Wang, Jinling Zhan, Hao Lu, Ranran Chang, Lizhong Qiu, Yaoqi Tian
Summary: In the study, it was found that crystal seeds with B-type structures could enhance the relative crystallinity and retrogradation rate of amylopectin, whereas crystal seeds with A-type structures had no significant effect on amylopectin retrogradation.
FOOD HYDROCOLLOIDS
(2021)
Article
Food Science & Technology
Erika Paulsen, Diego A. Moreno, Paula M. Periago, Patricia Lema
Summary: The study compared the effect of microwave bag cooking and conventional microwaving on the bioactive compound content and quality parameters of broccoli florets. Microwave bag cooking showed higher retention of glucosinolates and antioxidant capacity compared to conventional microwaving. Regardless of the cooking method, the glucosinolate profile remained unchanged after cooking.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Green & Sustainable Science & Technology
Diptimayee Nanda, N. R. Mandre
Summary: This study investigated the effect of different process variables on the responses of selective flocculation for low-grade iron fines using modified amphoteric starch as flocculant. It found that the maximum recovery and highest grade were achieved with specific values of pulp density, pH, and flocculant dosage.
JOURNAL OF SUSTAINABLE METALLURGY
(2023)
Article
Multidisciplinary Sciences
Hebat-Allah S. Tohamy, Mohamed El-Sakhawy, Samir Kamel
Summary: The adsorption behavior of chromium from aqueous solution by amphoteric Janus nitrogen-doped carbon quantum dots (AJ-N-CQDs) was investigated. The second-order adsorption kinetics model provided a better correlation with the experimental data, indicating a chemisorption process. The pseudo-first-order kinetics model was still suitable for describing the kinetics of Cr(VI) sorption, suggesting the involvement of chemisorption and physisorption in the adsorption of Cr(VI) by AJ-N-CQDs. The surface processes of external diffusion were found to be involved in the adsorption of Cr(VI) by AJ-N-CQDs.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Physical
Yuqi Yuan, Haijun Wang, Lingbo Xu, Haofeng Zhang, Yu Liu, Ping Lin, Peng Wang, Xiaoping Wu, Xuegong Yu, Can Cui
Summary: In this study, amphoteric imidazole was introduced to improve the quality of low-temperature processed CsPbI3 films. Imidazole formed strong coordination with Pb2+ and I- in perovskites, delaying the crystallization rate and leading to larger grains, improved crystallinity, and suppressed grain boundary defects. This research provides a facile strategy to enhance the performance of low-temperature processed CsPbI3 PSCs.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Multidisciplinary Sciences
Amit N. Shocron, Eric N. Guyes, Huub H. M. Rijnaarts, P. M. Biesheuvel, Matthew E. Suss, Jouke E. Dykstra
Summary: Harmful or valuable ionic species in seawater, brackish water, and wastewater are often amphoteric, weak acids or bases, making their removal challenging for conventional membrane technologies. Capacitive deionization (CDI) is an emerging membraneless technique that shows potential for removing pH-dependent species without chemical dosing, but its development is hindered by the complexities of pH dynamics and ion properties in a charging CDI cell. This study presents a theoretical framework for predicting the electrosorption of pH-dependent species in CDI cells and highlights counterintuitive design rules for efficient removal of amphoteric species like boron.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Polymer Science
Giorgio Luciano, Maurizio Vignolo, Elisabetta Brunengo, Roberto Utzeri, Paola Stagnaro
Summary: This paper reports on the formulation and characterization of composite coating materials susceptible to microwave heating, aiming to investigate their application in improving the energy efficiency of the rotomolding process. The experimental results show that the coatings with a ratio of 2:1 w/w of inorganic/MPS are the most microwave-susceptible materials. By applying these coatings to molds and using microwave-assisted laboratory uni-axial rotomolding process, polyethylene samples were successfully manufactured and characterized by calorimetry, infrared spectroscopy, and tensile tests.
Article
Biochemistry & Molecular Biology
Kamakshi Bankoti, Arun Prabhu Rameshbabu, Sayanti Datta, Piyali Goswami, Madhurima Roy, Dipankar Das, Sudip Kumar Ghosh, Amit Kumar Das, Analava Mitra, Sagar Pal, Dhrubajyoti Maulik, Bo Su, Paulomi Ghosh, Bikramajit Basu, Santanu Dhara
Summary: The dual cross-linked CsADM-Cl hydrogel, modified with ionic crosslinking using chitosan and covalent crosslinking using an iodine-modified cross-linker, demonstrated improved stiffness and reduced biodegradation rate post-crosslinking. It supported adhesion, proliferation, and migration of human foreskin-derived fibroblasts and keratinocytes, exhibited angiogenic potential, showed excellent antibacterial activity, and promoted rapid healing in full thickness burn wounds with superior angiogenesis and other positive healing indicators. The bioactive CsADM-Cl hydrogel has significant clinical potential as an injectable antibacterial matrix for treating challenging burn wounds.
Article
Polymer Science
Puja Das Karmakar, Aparna Shukla, Pralay Maiti, Soumit Chatterjee, Sagar Pal
Summary: RAFT polymerization was used to develop an amphiphilic bioconjugated graft-block copolymer with different hydrophobic segments, showing controlled molecular weight and narrow dispersity. The synthesized copolymer demonstrated cytocompatibility towards human cervical cancer cell lines, efficient loading and sustained release of a hydrophobic drug, suggesting its potential in biomedical science.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Priyapratim Patra, Abhay Shankar Patra, Asim Kumar Mukherjee, Sagar Pal
Summary: The study focused on the development of a novel flocculant utilizing CD-Meth. The synthesized material showed promising selectivity and faster settling of hematite particles, surpassing conventional starch flocculants in all aspects.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2021)
Article
Biochemistry & Molecular Biology
Arpita Roy, Preetam Guha Ray, Kalipada Manna, Chiranjib Banerjee, Santanu Dhara, Sagar Pal
Summary: The poly(N-vinyl imidazole) cross-linked beta-cyclodextrin hydrogel assembled through microwave-assisted free radical polymerization demonstrates superior blood clotting kinetics and biocompatibility, showing potential as a carrier for sustained release of drugs. Its rapid hemostatic behavior, cytocompatibility, hemocompatibility, and controlled drug release characteristics make it an excellent alternative for severe hemorrhagic conditions.
Article
Polymer Science
Puja Das Karmakar, Sagar Pal
Summary: In this study, a new pH-responsive amphiphilic graft copolymer was synthesized using ROP and RAFT techniques. The copolymer can efficiently self-assemble into micelles and is suitable for delivering drugs as a nanocarrier.
Article
Materials Science, Multidisciplinary
Puja Das Karmakar, Aniruddha Pal, Subhadip Bodhak, Sagar Pal
Summary: The study synthesized nanocomposites consisting of magneto-responsive gamma-Fe2O3 NPs and copolymers, with a regular core-shell morphology where the magnetic NPs act as the core and the copolymer as the shell. This developed nanocarrier has been found to be highly efficient in carrying a hydrophobic drug (naproxen).
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Arpita Roy, Kalipada Manna, Preetam Guha Ray, Santanu Dhara, Sagar Pal
Summary: A multiple-stimuli-responsive hydrogel with high stretchability and transparency has been synthesized in this study. It can be used to fabricate a flexible pressure sensor and a drug release carrier.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Kalipada Manna, Priyapratim Patra, Arpita Roy, Rakesh Kumar Roy, Krishna Chaitanya Sunka, Santanu Dhara, Niladri Patra, Sagar Pal
Summary: Biopolymeric micelles derived from bioinspired amphiphilic polymers have attracted attention as carriers for hydrophobic drugs. In this study, a hydrophobic monomer was synthesized and grafted onto a hydrophilic polymer backbone to obtain an amphiphilic copolymer. The copolymer showed controlled polymerization and pH-responsive reversible micellization behavior. The micelle formed from the copolymer was able to uptake and release a hydrophobic drug in a controlled manner.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Dipankar Das, Arpita Roy, Sagar Pal
Summary: This work developed a neutral, water-soluble, low-molecular-weight polysaccharide-dextrin-based hybrid hydrogel. Through in situ grafting and cross-linking, five grades of the hydrogel were prepared. The optimized grade exhibited pH-sensitive swelling behavior and cytocompatibility, and was used for antimicrobial drug delivery. The hydrogel demonstrated a sustained-release effect for amoxicillin and ornidazole, making it a potential oral drug delivery system.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Abanindra Nath Sarkar, Soni Kumari, Sheeja Jagadevan, Sagar Pal
Summary: This study presents the development of a solid-state mediator Ag-0-based-Z-scheme LDH/PANI/MAA/Ag heterojunction nanocomposite with intimate morphological contact interface. The synthesized nanocomposite showed enhanced photocatalytic degradation of emerging pollutants under sunlight irradiation and exhibited a large specific surface area and an excellent interface between its components. Additionally, the nanocomposite demonstrated antibacterial potential against Gram-positive and Gram-negative bacteria.
ACS APPLIED NANO MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Arpita Roy, Kalipada Manna, Sagar Pal
Summary: This review article focuses on the modern advances and developments of stimuli-responsive polymeric hydrogels and nanogels. Different synthetic designs and physicochemical tuning of stimuli sensitive hydrogels/nanogels are summarized. Stimuli-responsive hydrogels find extensive uses in the healthcare sector, including biosensing, controlled/sustained drug delivery, tissue and bone regeneration. These materials have significant properties and benefits for the healthcare sector.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Polymer Science
Shaon Dey, Arpita Roy, Kalipada Manna, Sagar Pal
Summary: A hydrogen bonded UCST polymer has been developed by grafting of methacrylamide and acrylic acid on dextran via free radical polymerization. The copolymer forms H-bonds between acid and amide groups at low temperature, making it insoluble in water. It becomes soluble beyond a certain temperature when the H-bonds collapse. The effects of pH, monomer composition, and polymer and salt concentration on the cloud point have been explored.
Article
Nanoscience & Nanotechnology
Arpita Roy, Subhendu Samanta, Koushik Singha, Pritiprasanna Maity, Nimmy Kumari, Animesh Ghosh, Santanu Dhara, Sagar Pal
ACS APPLIED BIO MATERIALS
(2020)
Article
Chemistry, Physical
Anthony Tabet, Thomas Gebhart, Guanglu Wu, Charlie Readman, Merrick Pierson Smela, Vijay K. Rana, Cole Baker, Harry Bulstrode, Polina Anikeeva, David H. Rowitch, Oren A. Scherman
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2020)
Article
Chemistry, Multidisciplinary
Andrea Cosola, Riccardo Conti, Vijay Kumar Rana, Marco Sangermano, Annalisa Chiappone, Joelle Levalois-Gruetzmacher, Hansjoerg Gruetzmacher
CHEMICAL COMMUNICATIONS
(2020)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
