Article
Engineering, Environmental
Shivayogi S. Narasagoudr, Saraswati P. Masti, Veena G. Hegde, Ravindra B. Chougale
Summary: Chitosan/Guar Gum/Gum Ghatti (CS/GG/GGh) active biobased films were successfully fabricated using cetrimide as a crosslinking and antimicrobial agent, resulting in improved performance and bactericidal effect. The films exhibited sensitivity to various bacterial strains.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Polymer Science
Vivek Puri, Ameya Sharma, Pradeep Kumar, Kamal Dua, Kampanart Huanbutta, Inderbir Singh, Tanikan Sangnim
Summary: Modified gum ghatti is a suitable approach for developing controlled drug delivery systems, and the toxicological study on animals showed no adverse effects after oral administration of pure and thiolated gum ghatti, suggesting their safety as potential candidates for drug formulation.
Article
Biochemistry & Molecular Biology
Pragnesh N. Dave, Pradip M. Macwan, Bhagvan Kamaliya
Summary: The study aimed to understand the drug release characteristics of Gg-cl-poly(NIPA-co-AA)/CoFe2O4 hydrogel containing metformin hydrochloride. Gum ghatti-based hydrogel with acrylic acid and N-isopropylacrylamide as graft copolymers was used for controlled release. The hydrogel was characterized using FTIR, SEM, TGA, and DSC. Drug release occurred through diffusion and polymer relaxation, regardless of drug solubility. In vitro release studies at different pH values showed pH 7.4 as the optimal pH for maximum release. The hydrogel loaded with metformin hydrochloride exhibited sustained release, fitting the Korsmeyer-Peppas model with a specific case II transport mechanism.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Bhagvan P. Kamaliya, Lakha Chopda, Pragnesh N. Dave
Summary: Conductive biopolymer hydrogels have been developed by adding CoFe2O4 nanoparticles to the hydrogel matrix, resulting in improved electrical properties. Higher loading of nanoparticles can affect the electrical conductivity of the hydrogel composite.
IRANIAN POLYMER JOURNAL
(2022)
Article
Chemistry, Physical
Dan Yang, Meng Du, Zia-ud Din, Shikui Yang, Lei Chen, Jie Cai, Jie Pang, Xi Chen, Wenping Ding
Summary: The GG/KGM/ZIF-8 composite aerogels (GKZ) were synthesized for CIP removal from water. The addition of GG promoted homogeneity but weakened the molecular interaction. ZIF-8 maintained crystal structure and improved dispersion on the aerogel surface. GKZ with 0.6% GG exhibited the highest adsorption capability for CIP.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Biochemistry & Molecular Biology
Shehala, Kirti Baranwal, Tulika Malviya, Lalit Mohan Dwivedi, Mani Prabha, Vandana Singh
Summary: The presence of saccharin (SH) was efficiently detected through the interference synthesis of gum ghatti (GG) capped silver nanoparticles (GGAgNps), with the detection further enhanced by combo capping with chitosan (Ch). The method successfully detected SH in commercially available real juice samples.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Engineering, Chemical
Pragnesh N. Dave, Lakha V. Chopda, Bhagvan P. Kamaliya
Summary: Water pollution leads to health and environmental issues. Modified biopolymers are effective adsorbents, and gum ghatti (GG) has good adsorption properties. In this study, GG was grafted with polyacrylic acid (PAA) and loaded with oxidized multiwalled carbon nanotubes (O-MWCNTs) to form GG-g-PAA/O-MWCNT hydrogel, which efficiently removed sodium diclofenac (SD).
CHEMICAL ENGINEERING & TECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Pragnesh N. Dave, Pradip M. Macwan, Bhagvan Kamaliya
Summary: The rheological properties of GNAGO hydrogels reinforced with graphene oxide (GO) were studied to modify their mechanical and thermal properties. The GNAGO hydrogel showed elastic behavior and had greater viscoelastic properties compared to the hydrogel without GO. The hydrogels exhibited non-Newtonian behavior with decreased viscosity at higher shear rates. The presence of GO particles within the hydrogel improved materials damping factors, and these hydrogels can be used for adsorption, controlled drug loading, and release.
MATERIALS ADVANCES
(2023)
Article
Materials Science, Multidisciplinary
Varun Prasath Padmanabhan, Natarajan Prakash, T. S. N. Sankara Narayanan, Ravichandran Kulandaivelu, Faruq Mohammad, Prasanna Kumar Obulapuram, Won Chun Oh, Suresh Sagadevan
Summary: This study investigates the influence of gum ghatti concentration on the porosity of hydroxyapatite, and observes superior properties for samples formed from higher GG concentration. The composite exhibits bioactivity and controlled drug release, with the potential for biomedical applications demonstrated through antimicrobial and cytotoxic tests.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Pharmacology & Pharmacy
Dibya Sinha, Shalmoli Seth, Avik Das, Uttam Kumar Bhattacharyya, Kushal Ghosh, Aniket Nandi, Payal Banerjee, Somasree Ray
Summary: This study developed a new biodegradable hydrogel film using the synergistic interaction of gum ghatti and pectin for slow release of antibiotics and wound healing promotion.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Prajwal Kulal, Vishalakshi Badalamoole
Summary: A porous hydrogel nanocomposite with high surface area and superparamagnetic behavior was synthesized by grafting poly(itaconic acid) on gum ghatti and incorporating magnetite nanoparticles. The nanocomposite showed excellent adsorption capacities for dyes and metal ions, following Freundlich isotherm model and pseudo second order kinetic process. It displayed spontaneous and endothermic adsorption, with potential for successful regeneration, making it an environmentally friendly adsorbent for water purification.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Debolina Ghosh, Megha Basak, Deepmoni Deka, Gopal Das
Summary: The innovation of novel chemosensor probes for the recognition of trace volatile organic compounds is critical due to their hazardous effect on the environment and human health. A nitro-group integrated quinoxaline probe was fabricated into guar gum and icarrageenan to develop compact, portable fluorogenic hydrogel sensors. Different characterizations were conducted to determine the overall compatibility of the hydrogel-based sensors for use as a smart rapid detection tool.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Pharmacology & Pharmacy
Nancy Kahali, Goutam Roy, Bibek Laha, Ritwika Mitra, Amit Kumar Nayak, Uttam Kumar Bhattacharyya, Somasree Ray
Summary: The study aimed to develop sustained releasing microparticles using chitosan and carboxymethylated derivative of gum ghatti (CMGG) through polyelectrolyte complexation. CMGG was synthesized using conventional Williamson ether synthesis method, and the degree of substitution was determined to be 0.40 ± 0.04%. Mebeverine HCl (M-HCl) loaded CMGG-chitosan microparticles were prepared by crosslinking with glutaraldehyde. The microparticles exhibited suitable particle sizes and drug release rates, and demonstrated good in vitro-in vivo correlation in pharmacokinetic evaluation.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Agricultural Engineering
Anurag Mehta, Gautam Sen, Jay Prakash Pandey
Summary: This research paper introduces a non-acrylamide based flocculant that is inherently safer. A novel cationic graft copolymer, synthesized using a microwave-assisted technique, shows superior flocculation performance in various mineral and nanoparticle suspensions. The results indicate the potential commercial use of this graft copolymer.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Polymer Science
Bhagvan Kamaliya, Pragnesh N. Dave, Pradip M. Macwan
Summary: The present study synthesized Gum ghatti-cl-poly(acrylic acid)/-o-MWCNT hydrogel through free radical copolymerization method, and explored its potential applications in agriculture, medicine, and pharmaceuticals.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Materials Science, Biomaterials
Inayat B. Pathan, Santosh J. Munde, Santosh Shelke, Wahid Ambekar, C. Mallikarjuna Setty
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2019)
Article
Materials Science, Biomaterials
Inayat B. Pathan, Santosh J. Munde, Santosh Shelke, Wahid Ambekar, C. Mallikarjuna Setty
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2019)
Article
Pharmacology & Pharmacy
Dhaval P. Patel, Chitral Mallikarjuna Setty, Gaurav N. Mistry, Santnu L. Patel, Tarun J. Patel, Pritesh C. Mistry, Amar K. Rana, Pritesh K. Patel, Rishabh S. Mishra
Article
Materials Science, Textiles
Raghavendra V. Kulkarni, Vaibhav V. Baraskar, C. Mallikarjun Setty, Biswanath Sa
FIBERS AND POLYMERS
(2011)
Article
Pharmacology & Pharmacy
C. Mallikarjuna Setty, D. V. K. Prasad, V. R. M. Gupta, B. Sa
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2008)
Article
Biochemistry & Molecular Biology
Raghavendra V. Kulkarni, V. Sreedhar, Srinivas Mutalik, C. Mallikarjun Setty, Biswanath Sa
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2010)
Article
Biochemistry & Molecular Biology
C. Mallikarjuna Setty, Anand S. Deshmukh, Aravind M. Badiger
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2014)
Article
Biochemistry & Molecular Biology
C. Mallikarjuna Setty, Anand S. Deshmukh, Aravind M. Badiger
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2014)
Article
Polymer Science
Raghavendra V. Kulkarni, Chitrali Mallikarjun Setty, Biswanath Sa
JOURNAL OF APPLIED POLYMER SCIENCE
(2010)
Article
Chemistry, Applied
Rashmi Boppana, Raghavendra V. Kulkarni, Srinivas S. Mutalik, C. Mallikarjun Setty, Biswanath Sa
JOURNAL OF MICROENCAPSULATION
(2010)
Article
Polymer Science
Raghavendra V. Kulkarni, Yogesh J. Wagh, C. Mallikarjun Setty, Biswanath Sa
POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING
(2011)
Article
Nanoscience & Nanotechnology
Inayat Bashir Pathan, C. Mallikarjuna Setty
DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES
(2012)
Review
Pharmacology & Pharmacy
Inayat Bashir Pathan, C. Mallikarjuna Setty
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
(2009)
Article
Education, Scientific Disciplines
Maulesh G. Joshi, C. M. Setty, A. S. Deshmukh, Y. A. Bhatt
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
(2010)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
