Article
Chemistry, Applied
Gemma C. Porter, Donald R. Schwass, Geoffrey R. Tompkins, Sharan K. R. Bobbala, Natalie J. Medlicott, Carla J. Meledandri
Summary: The synthesis and incorporation of antimicrobial silver nanoparticles (AgNPs) into an alginate hydrogel showed improved properties and antibacterial effects, with controlled release of silver ions for specific microorganisms and biofilms.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Wafa Al-Gethami, Noha Al-Qasmi
Summary: This study aimed to prepare antimicrobial nanocomposites consisting of alginate, chitosan, and camptothecin. The results showed a strong chemical interaction between alginate and chitosan, and successful loading of camptothecin in both Ca-Alg(2)/CPT and Ca-Alg(2)-CH/CPT nanomaterials. Antimicrobial tests revealed that Ca-Alg(2)-CH/CPT nanocomposite was more effective against Escherichia coli and Klebsiella pneumoniae, while Ca-Alg(2)/CPT was less efficient in killing all three types of bacteria. PCR analysis indicated changes in bacterial genetic material due to the nanomaterial processing.
Article
Chemistry, Inorganic & Nuclear
Parameshwar Jakinala, Harikrishna Naik Lavudi, Neelima Angali, Santhosh Ganderla, Krishna K. Inampudi, Sai Balaji Andugulapati, M. Srinivas, Madhumohan Rao Katika
Summary: A novel approach using buffalo grass extract for the formation of ZnO-Ag nanocomposites is cost-effective, eco-friendly, and has high anticancer and antibacterial activities. Phenol and octadecanoic acid are the major phytochemical compounds involved in the biosynthesis of ZnO-Ag nanocomposites. The biosynthesized ZnO-Ag nanocomposites show strong antibacterial activity, with significant cell death observed in oral squamous cell carcinoma cell lines, suggesting potential applications as antimicrobial agents and for human carcinoma treatments.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Polymer Science
Elizaveta S. Permyakova, Anton M. Manakhov, Philipp V. Kiryukhantsev-Korneev, Denis V. Leybo, Anton S. Konopatsky, Yulia A. Makarets, Svetlana Yu. Filippovich, Sergey G. Ignatov, Dmitry V. Shtansky
Summary: In this study, ZnO-modified polycaprolactone nanofibers were developed and showed high antibacterial and antifungal activity against Gram-positive and Gram-negative pathogenic bacteria and pathogenic fungi.
Article
Nanoscience & Nanotechnology
Minho Lee, Song- Han, Changkyu Kim, Subramaniam Velumani, Arum Han, Abdel Hadi Kassiba, Homero Castaneda
Summary: The ultrathin nanocomposite coatings of ZrO2/ZnO/TiO2 on stainless steel were found to provide excellent corrosion protection and antimicrobial activity. The coating exhibited significantly higher impedance values compared to uncoated steel, and promoted cell proliferation and effective bacterial killing efficiency.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Pharmacology & Pharmacy
Bruno Altran Costa, Marina Paiva Abucafy, Thulio Wliandon Lemos Barbosa, Bruna Lallo da Silva, Rafael Bianchini Fulindi, Guilherme Isquibola, Paulo Inacio da Costa, Leila Aparecida Chiavacci
Summary: Loading antibiotic drugs into zeolitic imidazolate frameworks (ZIFs), in combination with ZnO nanoparticles, can improve drug delivery efficiency and reduce side effects. This association allows for controlled release of active moieties and shows good antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa.
Article
Environmental Sciences
Karanpal Singh, Nancy, Harpreet Kaur, Pushpender Kumar Sharma, Gurjinder Singh, Jagpreet Singh
Summary: The study synthesized undoped and Cobalt-doped zinc oxide nanoparticles (Co doped ZnO NPs) and confirmed the incorporation of the Co dopant through spectroscopic and microscopic techniques. The Co-doped ZnO NPs showed a red shift in the UV-absorption spectra and a decrease in band gap value, indicating successful integration of Co2+ ions into the ZnO matrix. The synthesized NPs exhibited excellent photocatalytic and antimicrobial activity, with 1% Co-doped ZnO showing the highest photocatalytic efficiency.
Article
Chemistry, Applied
Hanan Albalwi, Faten Ismail Abou El Fadl, Mohamed M. Ibrahim, Manal F. Abou Taleb
Summary: This study successfully degraded the model anionic dye Basic Blue 3 using prepared Ca-alginate/silver (Ca-ALG/Ag) nanocomposite beads as catalyst. The physicochemical properties of the nanocomposite beads were characterized using various techniques, confirming their effectiveness in dye degradation. Different kinetic and isothermal models revealed that the degradation process using Ca-ALG/Ag nanocomposite beads as catalyst best fit the pseudo-second-order kinetic model and Langmuir isotherm model.
APPLIED ORGANOMETALLIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Mai M. Mohamed, Asmaa Sayed, Ghada A. Mahmoud
Summary: Nanocomposite biohydrogels containing Xanthan gum, Agar, and Gelatin with different ratios of Zinc oxide nanoparticles (ZnO-NPs) were prepared using gamma irradiation and methylene bis acrylamide (MBAm) as a crosslinking agent. The hydrogels were characterized by various techniques including FTIR, XRD, and TGA. AFM and SEM were used to analyze the surface features and morphology. The results showed that both gamma irradiation and ZnO-NPs improved the gel content of the biohydrogel nanocomposite, with the highest gel content achieved when 0.5x10(-2) g of ZnO-NPs was added. The nanocomposite biohydrogels exhibited good thermal stability and antimicrobial activity, making them suitable for potential biological applications.
Article
Polymer Science
Fatma Mohamed, Asmaa Ahmed, Omayma F. Abdel-Gawad
Summary: Antibiotic nanocomposite polymers hold great potential in treating various pathogens, and the development of new composite materials with antibacterial properties is important for industrial applications.
Article
Materials Science, Multidisciplinary
Faisal Mukhtar, Tauseef Munawar, Muhammad Shahid Nadeem, Muhammad Naveed ur Rehman, Muhammad Riaz, Faisal Iqbal
Summary: The study synthesized a tri-phase direct dual S-scheme ZnO-V2O5-WO3 heterostructured nanocomposite using a co-precipitation method. The nanocomposite demonstrated high antibacterial and photocatalytic activity, with a significant degradation efficiency of various dyes under direct sunlight. Different schematic models illustrated the photocatalytic reaction mechanism, with the enhanced performance explained by the S-scheme for efficient charge carrier separation.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Yecheng Feng, Wenjing Yang, Xiaojing Shi, Xubo Zhao
Summary: This study developed a pH-responsive alginate-based assembly for selective drug delivery in cancer treatment. The assembly disassembles under acidic conditions to release the drug and inhibit tumor growth. These findings inspire the development of drug delivery systems for cancer therapy.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Nanoscience & Nanotechnology
Qiang Li, Yulan Hu, Bingjian Zhang
Summary: Researchers have developed a composite material containing ZnO nanoparticles, calcium phosphate oligomers, and oxidized sodium alginate, which exhibits good antimicrobial properties. The composite material shows potential cultural heritage conservation value when used as a protective coating on sandstone.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Elias Takele, Raji Feyisa Bogale, Gemechu Shumi, Girmaye Kenasa
Summary: The green synthesis of metal oxide nanocomposites using Zingiber officinale rhizome extract as a reducing agent and stabilizer was successfully carried out. These nanocomposites showed effective antibacterial activity against Gram-positive and Gram-negative bacteria. The characterization of the nanocomposites was done using UV-Vis spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, and X-ray diffraction (XRD).
JOURNAL OF CHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Ao Zhang, Zhe Cao, Luying Zhao, Qian Zhang, Liping Fu, Jiang Li, Tao Liu
Summary: In this study, a alginate lyase gene called aly644 was obtained from Antarctic macroalgae-associated microbes. The gene exhibited optimal reaction conditions at 50 degrees Celsius and pH 7.0. It showed high catalytic activity towards sodium alginate, with a V-max value of 112.36 mg/mL min and a K-m value of 16.75 mg/mL. Aly644 demonstrated bifunctional activity by hydrolyzing both polyguluronic acid and polymannuronic acid. The products of Aly644 degradation of sodium alginate were di- and trisaccharides, which inhibited the growth of plant pathogens Phytophthora capsici and Fulvia fulva. Aly644 has potential industrial applications in the production of low degree of polymerization alginate oligosaccharides for use as natural antimicrobial agents in green agriculture.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Polymer Science
Athanasios D. Porfyris, Stamatina N. Vouyiouka, Adriaan S. Luyt, Dimitrios M. Korres, Sarah S. Malik, Soumia Gasmi, Michael Grosshauser, Rudolf Pfaendner, Constantine D. Papaspyrides
Summary: The article focuses on the development of customized polyolefin formulations with low flammability and high weathering resistance to provide value-added polyethylene grades with extended service lifetime. The compounds achieved V0 classification in UL94V flammability tests while maintaining mechanical properties to a large extent, showing promise for outdoor applications where long-term weathering stability and flame retardance are important.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Chemistry, Physical
Sebastian Hartweg, Gustavo A. Garcia, Dusan K. Bozanic, Laurent Nahon
Summary: A comparative study of VUV photoelectron spectroscopy and photoelectron circular dichroism was conducted between gas phase enantiomers of the amino acid serine and their homochiral nanoparticles, revealing a significant asymmetry and demonstrating the potential of the PECD technique as a sensitive probe of condensation effects in chiral aerosol particles.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Physical
Dusan K. Bozanic, Radovan Dojcilovic, Jelena D. Pajovic, Dragana Tosic, Dusko Dudic, Matthieu Refregiers, Vladimir Djokovic
Summary: In this study, fluorescent nanocomposite films were prepared by solution mixing of polyvinyl alcohol (PVA) and tryptophan functionalized silver (AgTrp) nanoparticles. The distribution of AgTrp nanoparticles within the polymer matrix was tracked using synchrotron excitation deep-ultraviolet fluorescence imaging. The presence of AgTrp nanoparticles resulted in the pronounced growth of dendrite-like structures, which was confirmed by various imaging techniques. Both tryptophan and AgTrp nanoparticles affected the thermal properties of the matrix, reducing crystallinity and increasing the glass transition temperature of PVA. Furthermore, the films showed a significant increase in conductance under illumination with 250 nm light, with the relative changes reaching almost 200% compared to the dark condition.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Physical
Danijela Danilovic, Aleksandar R. . Milosavljevic, Pitambar Sapkota, Radovan Dojcilovic, Dragana Tosic, Nenad Vukmirovic, Milan Jocic, Vladimir Djokovic, Sylwia Ptasinska, Dusan K. Bozanic
Summary: In this study, a simple route for fabricating silver-bismuth iodide nanoplatelets was reported. The valence band electronic structure of the isolated nanoplatelets was investigated, and the optical properties were analyzed using UV-vis absorption and photoluminescence spectroscopies, as well as density functional theory calculations.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Polymer Science
Mafereka F. T. Mosoabisane, Adriaan S. Luyt, Cornelia G. C. E. van Sittert
Summary: This article investigates the influence of molecular interaction and morphology on the thermal and mechanical properties of LLDPE/wax blends. The cooling rate is not sufficient to determine the interactions between the molecules in the blends, therefore, samples were cooled at different rates to model the thermal and mechanical properties. The results show the cocrystallization of wax with LLDPE and confirm the rapid crystallization of both components.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Engineering, Electrical & Electronic
Danijela Danilovic, Dusan K. Bozanic, Gustavo A. Garcia, Laurent Nahon, Una Stamenovic, Vesna V. Vodnik, Vladimir Djokovic
Summary: The angle-resolved photoelectron spectroscopy of isolated silver sulfide nanoparticles was conducted using velocity map imaging technique. The results show the maximum energy of the valance band and the minimum energy of the conduction band of the nanoparticles, and the onset of inelastic scattering at around 1 eV.
OPTICAL AND QUANTUM ELECTRONICS
(2022)
Article
Polymer Science
Filip Marinkovic, Blanka Skipina, Danijela Vukovic, Ernst H. G. Langner, Adriaan S. Luyt, Dusko Dudic
Summary: This article investigates the changing dielectric properties of a LDPE/ZIF-8 composite under gamma radiation. The study found that the conductivity of the samples increased linearly with increasing radiation dose, while the change in dielectric permittivity showed nonlinear behavior.
JOURNAL OF MACROMOLECULAR SCIENCE PART B-PHYSICS
(2022)
Article
Polymer Science
Junaid Saleem, Moghal Zubair Khalid Baig, Adriaan Stephanus Luyt, Rana Abdul Shakoor, Said Mansour, Gordon McKay
Summary: This study reports the production of reusable oil sorbent films by upcycling waste PE and PP. The sorbent films have a porous structure, good oleophilic properties, and high oil uptake capacity. Additionally, the thermal and mechanical properties of the films were also examined.
Article
Materials Science, Multidisciplinary
Junaid Saleem, Zubair Khalid Baig Moghal, Adriaan S. Luyt, R. A. Shakoor, Gordon McKay
Summary: Spin coating is commonly used to prepare thin films with uniformity and controlled thickness. However, it has not been successful in producing free-standing thin films of polyolefins due to their insufficient strength. In this study, we have achieved free-standing thin films of polyolefins, such as polyethylene, with varying thickness. These films can be used for hydrophobic coating, filtration membranes, and oil-sorbents.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Polymer Science
Junaid Saleem, Zubair Khalid Baig Moghal, Rana A. Shakoor, Adriaan S. Luyt, Gordon McKay
Summary: Mixed polyolefin-based waste requires immediate attention to mitigate its negative impact on the environment. The separation of these plastics is energy-intensive due to their similar densities, and they cannot be blended without compatibilizers due to their inherent incompatibility. This study presents non-wettable microporous sheets made from recycled polyethylene (PE) and polypropylene (PP), which demonstrate efficient oil-water separation and high reusability. These findings emphasize the importance of sustainable solutions for plastic recycling and mitigating oil spill problems.
Article
Chemistry, Physical
Danijela Danilovic, Aleksandar R. Milosavljevic, Pitambar Sapkota, Radovan Dojcilovic, Dragana Tosic, Nenad Vukmirovicc, Milan Jocic, Vladimir Djokovic, Sylwia Ptasinska, Dusan K. Bozanic
Summary: This study reports a lead-free material as a possible replacement for methylammonium lead halides in optoelectronic applications, which exhibits chemical stability and non-toxicity. Ag-Bi-I colloidal nanoplatelets were synthesized through a simple method in acetonitrile, and their optical and electronic properties were characterized by experiments and calculations.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Religion
Vladimir Djokovic
Summary: This article discusses the problem of unity or disunity of the self from the perspective of various disciplines. The first part focuses on the concept of self-fragmentation in Human sciences, particularly in Psychology and Cognitive sciences, and its relationship to religious views. The second part examines Jacques Derrida's work on deconstruction and its implications for the fragmentation of the self. The final part explores the potential splitting of the conscious self of the observer in quantum mechanical experiments.
EUROPEAN JOURNAL OF SCIENCE AND THEOLOGY
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
