Article
Biochemistry & Molecular Biology
Adriana Nicoleta Frone, Marius Ghiurea, Cristian Andi Nicolae, Augusta Raluca Gabor, Stefania Badila, Denis Mihaela Panaitescu
Summary: The growing concern about environmental pollution has led to an increased demand for biobased and biodegradable materials in the packaging industry. This study focuses on the effect of two different cellulosic reinforcements and plasticized poly(3-hydroxybutyrate) (PHB) on the properties of poly(lactic acid) (PLA). The results demonstrate the great potential of using cheap cellulose fibers obtained from wood waste to produce PLA/PHB-based materials for packaging applications as an alternative to fossil-based materials.
Article
Chemistry, Multidisciplinary
Mark D. Lawley, David Boon, Lisa Y. Stein, Dominic Sauvageau
Summary: Switchable solvents are promising candidates for the recovery of bioproducts, such as PHB, and can dissolve PHB within a certain temperature range.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Review
Agricultural Engineering
Ranjna Sirohi, Vivek Kumar Gaur, Ashutosh Kumar Pandey, Sang Jun Sim, Sunil Kumar
Summary: Utilizing fruit waste for PHB production is an effective method, with pineapple and mixed fruit waste shown to be effective substrates. Future research should focus on the pre-processing of fruit waste and the impact of fermentation conditions on PHB production.
BIORESOURCE TECHNOLOGY
(2021)
Review
Polymer Science
Catalina Diana Usurelu, Stefania Badila, Adriana Nicoleta Frone, Denis Mihaela Panaitescu
Summary: Poly(3-hydroxybutyrate) (PHB) is a promising material for packaging and biomedical fields due to its biodegradability, biocompatibility, and good properties. The addition of cellulose nanocrystals (CNCs) can improve its weaknesses and enhance its performance. Choosing the right processing technology and surface treatment for CNCs is crucial for obtaining good properties and interfacial adhesion in the resulting nanocomposites.
Article
Thermodynamics
D. S. Dias, M. S. Crespi, C. A. Ribeiro, M. Kobelnik
Summary: This study investigated the thermal behavior of polymeric blends prepared from recyclable RPET and PHB, showing little interaction between them and a strong dependence of the blends on heating rates. The kinetic parameters suggested similar initial kinetic behavior for two blends, while the third sample exhibited different behavior compared to the others.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2021)
Article
Engineering, Environmental
Peter Polyak, Fruzsina Mackei, Agoston Toth, Marton Bredacs
Summary: The market share of microbial polyesters, despite their sustainability, biodegradability, and biocompatibility, is still marginal due to poor thermal stability and degradation during processing. To address these issues, the thermal stability of poly(3-hydroxybutyrate) was improved using a stabilizer system based on pomegranate extract. Additionally, a computational method based on a hybrid model was developed to estimate the mechanical properties of processed microbial polyesters from IR data.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Plant Sciences
Nannaphat Sukkasam, Aran Incharoensakdi, Tanakarn Monshupanee
Summary: Various photoautotrophic cyanobacteria can increase the accumulation of bioplastic poly(3-hydroxybutyrate) (PHB) through chemical stimulation, which is beneficial for energy storage and bioplastic production.
PLANT AND CELL PHYSIOLOGY
(2022)
Article
Engineering, Chemical
Peter Polyak, Janos Moczo, Bela Pukanszky
Summary: A new method based on fractionation is proposed in this article for producing nearly monodisperse poly(3-hydroxybutyrate) particles. This method separates particles by taking advantage of the velocity of their movement in a homogeneous fluid, which is dependent on particle diameter. The method consists of two steps: producing a set of particles with a wide range of diameters using the emulsion-suspension method, and separating them into fractions on hydrogel columns. The proposed method is beneficial for drug carrier matrix preparation as it allows precise control and modeling of drug release kinetics.
Article
Biochemistry & Molecular Biology
Changfeng Miao, Dong Meng, Yuling Liu, Fang Wang, Lu Chen, Zhaosong Huang, Xiangyu Fan, Pengfei Gu, Qiang Li
Summary: This study identified a phaC(R) gene encoding PHA synthase in Rhodoligotrophos defluvii, and successfully synthesized different content and structural PHA copolymers under different carbon source conditions, achieving efficient biosynthesis.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Joseph Kinyanjui Muiruri, Jayven Chee Chuan Yeo, Tang Yuanting Karen, Ke Li, Enyi Ye, Xian Jun Loh, Zibiao Li
Summary: Nature triggers the phase change of plant metabolites from solid to liquid to survive in hot environments. Taking cues from this, carvacrol, a plant metabolite, can dissolve high concentration poly(3-hydroxybutyrate) (PHB) rapidly, and the solvent can be fully recovered by adding anti-solvents.
Article
Agricultural Engineering
Laura Gonzalez-Resendiz, Leon Sanchez-Garcia, Ingrid Hernandez-Martinez, Gabriel Vigueras-Ramirez, Luis Felipe Jimenez-Garcia, Reyna Lara-Martinez, Marcia Morales-Ibarria
Summary: A new wild-type strain of cyanobacteria capable of producing PHB through photoautotrophic processes was identified, showing varying productivity and CO2 capture capabilities under different pH conditions, with significant PHB production even under N-starving conditions.
BIORESOURCE TECHNOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Demetres Briassoulis, Philippos Tserotas, Ioanna-Georgia Athanasoulia
Summary: Polyhydroxyalkanoates (PHAs), a group of bio-based polymeric materials formed by microorganisms, include the well-known member Poly(3-hydroxybutyrate) (PHB). Despite PHB's high biodegradability and biocompatibility, its low ductility and susceptibility to thermal degradation limit its applications. Alternative strategies such as modification and blending are needed to enhance the performance of PHB for producing bio-based plastics with improved properties.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Multidisciplinary
Piotr Jablonski, Dariush Nikjoo, Johan Warna, Knut Irgum, Jyri-Pekka Mikkola, Santosh Govind Khokarale
Summary: This report introduces a sustainable, metal-free, and single solvent-based reaction approach for the selective depolymerization of biopolymers to industrially valuable chemicals. The study investigates the influence of different reaction parameters on the conversion yield and efficiency.
Article
Biochemistry & Molecular Biology
Yonghui Zhou, Evina Katsou, Mizi Fan
Summary: This study investigated the interface bonding of CMC/PHBV biocomposites and the impact of coupling agents. The results indicated that coupling agents MA and VTMS covalently bonded to CMC and PHBV, resulting in improved distribution and embedment of CMC in PHBV matrix, leading to enhanced interfacial bonding and superior mechanical properties and thermal stability of the biocomposites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Maria Rapa, Laura Mihaela Stefan, Ana-Maria Seciu-Grama, Alexandra Gaspar-Pintiliescu, Ecaterina Matei, Catalin Zaharia, Paul Octavian Stanescu, Cristian Predescu
Summary: This study aimed to prepare biocomposites consisting of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), bacterial cellulose (BC), and alpha-tocopherol by melt processing for potential biomedical applications. The addition of BC improved the melt processing and surface roughness of the biocomposites, and increased cytocompatibility, allowing for cell proliferation and secretion of extracellular matrix.
Article
Materials Science, Ceramics
I. C. Pinto, R. F. Falci, V. A. G. Rivera, T. Guerineau, S. LaRochelle, Y. Messaddeq
Summary: This paper provides a better understanding of the mechanism of interactions between Ce3+ and Er3+ ions in a tungsten-tellurite glass. Ce4+ and Ce3+ ions were obtained in an Er3+-doped tellurite glass by adding different concentrations of CeO2. Under a 980 nm excitation, a series of interactions between Ce3+<-> Er3+ were observed, leading to a subtle increase in the Er3+ emission intensity in the near-infrared region for 0.1 mol% of CeO2, followed by a decrease in the emission intensity for higher CeO2 concentration without any significant increase in the bandwidth. The visible upconversion emission intensity also decreased with the addition of CeO2. These interactions are achieved through coupling and energy transfer.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Ceramics
Amanda Maria Claro, Caroline Cassia Alves, Kelvin Sousa dos Santos, Euzane Gomes da Rocha, Marina de Lima Fontes, Gustavo Claro Monteiro, Gustavo Senra Goncalves de Carvalho, Jose Mauricio Almeida Caiut, Andrei Moroz, Sidney Jose Lima Ribeiro, Hernane S. Barud
Summary: Tissue engineering is a multidisciplinary field that aims to improve health and quality of life by restoring tissue and organ functions. Cells and scaffolds are the major components of tissue engineering, and 3D porous scaffolds are more suitable for tissue regeneration. In this study, a regenerated cellulose sponge was used as a sacrificial template to synthesize a three-dimensional porous alumina-silica scaffold.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
York E. Serge-Correales, David Neumeyer, Sajjad Ullah, Robert Mauricot, Qilin Zou, Sidney J. L. Ribeiro, Marc Verelst
Summary: In this study, oleic acid-stabilized ZnGa2O4 nanoparticles were successfully synthesized with controlled size and monodispersity. The size and persistent luminescence of the nanoparticles could be further increased using a seed mediated approach. Surface modification strategies involving poly(acrylic acid) or cysteamine in conjunction with BF4- provided long-term colloidal stability and enhanced persistent luminescence.
Article
Materials Science, Multidisciplinary
Filipe A. Couto, Kelly T. Paula, Moliria V. Santos, Sidney J. L. Ribeiro, Cleber R. Mendonca
Summary: Periodic dielectric structures have the potential to control light propagation at micro-and nanoscale efficiently with low losses. Among various techniques, femtosecond Laser-Induced Forward Transfer (fs-LIFT) is a promising method due to its simplicity and ability to process different materials while maintaining their integrity. In this work, well-ordered periodic arrays of silk fibroin (SF) microstructures were successfully printed using fs-LIFT. Finite-element simulations were performed to study their response to electromagnetic radiation in the near to mid-infrared range with consideration of the substrate. The results showed a decrease in reflectivity, which was supported by experimental results. Coating the structures with a higher index dielectric material further enhanced the decrease in reflectivity in the mid-infrared range. This study demonstrates a straightforward approach to fabricate ordered arrays of SF microstructures, which have potential applications as controllable reflectivity coatings in the near to mid-infrared range.
Review
Polymer Science
Thales Alves Faraco, Marina de Lima Fontes, Rafaella Takehara Paschoalin, Amanda Maria Claro, Isabella Salgado Goncalves, Mauricio Cavicchioli, Renan Lira de Farias, Marco Cremona, Sidney Jose Lima Ribeiro, Hernane da Silva Barud, Cristiano Legnani
Summary: With the progress of nanotechnology, organic electronics have gained momentum, especially in the production and development of electronic devices based on organic semiconductors. In recent years, there has been great interest in using organic electronics in various fields, including biomedicine. Bacterial nanocellulose (BNC) has attracted attention as an advanced material for its unique physical and mechanical properties, making it a versatile substrate for organic electronics applications. This review focuses on BNC production methods, properties, and applications, particularly in OLEDs and flexible OLEDs (FOLEDs), and discusses the future progress of BNC-based flexible substrate nanocomposites.
Article
Nanoscience & Nanotechnology
Victor Fuertes, Nicolas Gregoire, Philippe Labranche, Natalie Hamada, Brice Bellanger, Yannick Ledemi, Sophie LaRochelle, Younes Messaddeq
Summary: Engineering silica optical fibers by nanoparticle doping is a promising technology that allows the introduction of new functionalities and extends their applicable fields. This study demonstrates the possibility of doping optical fibers with tetragonal cubic-shaped and monoclinic rod-shaped YPO4 nanocrystals, in terms of shape, composition, and structure. The findings also open up new avenues to study shape-dependent properties of rare-earth orthophosphate (REPO4) nanostructures in optical fibers, which will have a significant impact in various applications.
ACS APPLIED NANO MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Victor Fuertes, Adolfo del Campo, Nicolas Gregoire, Philippe Labranche, Jose Francisco Fernandez, Younes Messaddeq
Summary: An in-depth study of nanoparticle-doped optical fibers using confocal Raman microscopy, Rayleigh light-scattering microscopy, and scanning electron microscopy (SEM) reveals the crystallization structures and size-dependent Raman shifts of YPO4 nanocrystals in the fiber core. The study also evaluates the Raman properties of the nanocrystals at different temperatures, observing linear phonon softening behavior. These findings provide new insights into the characteristics of nanoparticle-doped optical fibers and open up possibilities for further research in this field.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Electrical & Electronic
Magali Ozon, Antoine Frasie, Gabriel Gagnon-Turcotte, Mourad Roudjane, Laurent Bouyer, Ghyslain Gagnon, Younes Messaddeq, Benoit Gosselin
Summary: This work presents a system for measuring and analyzing motion using a portable electronic device and a flexible fiber sensor. The system includes a new sensor interface circuit that measures the impedance of the fiber, which is composed of multi-walled carbon nanotubes and polydimethylsiloxane elastomer. The measured data is transmitted to a laptop via Bluetooth, allowing for easy integration into a smart garment. The system was assessed on a robotic arm and through various exercises on 5 participants, showing good measurement performance and accuracy.
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS I-REGULAR PAPERS
(2023)
Article
Chemistry, Physical
Brice Bellanger, Wagner Correr, Emmanuel Veron, Cecile Genevois, Yannick Ledemi, Mathieu Allix, Younes Messaddeq
Summary: The influence of the structural environment of lanthanide ions on the co-doping Faraday effect in fluorophosphate glasses and glass ceramics is studied. The crystallization process and the composition law of TbOF glass ceramics are investigated, and the Verdet constants of co-doped glass ceramics are compared to those of parent glasses. It is found that the structural organization around the lanthanide cation site increases the co-doping influence on the Faraday Effect by optimizing the superexchange interaction.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Materials Science, Ceramics
V. Fuertes, F. E. Durak, V. A. G. Rivera, N. Gregorie, S. Morency, M. Sharma, L. Wang, Y. Messaddeq, S. LaRochelle
Summary: By adjusting the glass composition, preform, and fiber fabrication conditions, the number density of bismuth active centers (BACs) in the E and S bands can be significantly tailored and increased, resulting in enhanced luminescence and gain.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Materials Science, Ceramics
Samar Aouji, Theo Guerineau, Rayan Zaiter, Evelyne Fargin, Younes Messaddeq, Thierry Cardinal
Summary: In this study, two barium gallo-germanate glass series were investigated to understand the impact of yttrium introduction on their physicochemical properties and crystallization behavior. Yttrium oxide (YO3/2) was added into the glass matrix or substituted for gallium oxide in concentrations ranging from 1 to 20 mol%. Raman spectroscopy was used to analyze the glass structure, while thermal, optical, thermo-mechanical, and physical properties were examined. The introduction of yttrium ions increased various properties of the glasses, such as glass transition temperature, crystallization temperature, softening temperature, coefficient of linear thermal expansion, and density. Competition between the gallo-germanate zeolite-type phase and the yttrium-containing phase was observed, with the yttrium introduction inhibiting the formation of surface crystallization in the glasses from 13 mol% of YO3/2 onwards.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Materials Science, Ceramics
Victor Fuertes, Nicolas Gregoire, Philippe Labranche, Steohane Gagnon, V. A. G. Rivera, Sophie LaRochelle, Younes Messaddeq
Summary: Rayleigh scattering enhanced nanoparticle-doped silica-based optical fibers have gained attention for distributed sensing applications. Adding in situ growth Ba-rich nanoparticles to alkaline earth-based compositions allows customization of nucleated nanoparticles in the preform core. The fiber drawing process further impacts their size and composition, resulting in optimized trade-off between Rayleigh scattering enhancement and optical losses, enabling sensing lengths from 6.5 to 28.7 m. The ability to easily tailor Ba-rich nanoparticle characteristics strengthens the potential of in situ grown alkaline earth nanoparticles for future distributed optical fiber sensors.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2023)
Article
Energy & Fuels
Marivone Gusatti, Daniel A. R. Souza, Sidney J. L. Ribeiro, Marcelo Nalin
Summary: In this study, a novel all-solid-state electrochromic device (ECD) was prepared using a cost-effective and industrially applicable spray coating technique, eliminating the use of indium tin oxide (ITO), tungsten(VI) oxide (WO3), and Li+ or any other liquid/gel electrolytes. The fabricated ECD demonstrated a reversible color change between a light-blue (off) and darkblue (on) state, with good and homogeneous contrast. The device exhibited a coloration efficiency of 174.62 cm2/C and cycle stability for at least 150 times.
SOLAR ENERGY MATERIALS AND SOLAR CELLS
(2023)
Article
Chemistry, Multidisciplinary
Antsar R. Hlil, Jean-Sebastien Boisvert, Hatem M. Titi, Yalina Garcia-Puente, Wagner Correr, Sebastien Loranger, Jyothis Thomas, Ali Riaz, Younes Messaddeq, Raman Kashyap
Summary: This study thoroughly investigated the impact of femtosecond (fs) laser on PDMS-based composites, revealing the influence of photoinitiators on mechanical properties and refractive index change of PDMS. It showed a significant improvement in optical performance levels of PDMS composites, providing guidance for future research in photonics and polymer chemistry.
Article
Chemistry, Multidisciplinary
Antsar R. Hlil, Jean-Sebastien Boisvert, Hatem M. Titi, Yalina Garcia-Puente, Wagner Correr, Sebastien Loranger, Jyothis Thomas, Ali Riaz, Younes Messaddeq, Raman Kashyap
Summary: This study characterizes the effect of fs-laser writing on various PDMS-based composites, demonstrating the influence of photoinitiators on the mechanical and optical properties of PDMS. The findings provide insights for selecting photoinitiators for specific applications in photonics and polymer chemistry.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
