Review
Polymer Science
Hao Hu, Binshen Wang, Bihua Chen, Xi Deng, Guohua Gao
Summary: Swellable poly(ionic liquid)s (SPILs) are ionic polymers with unique swelling ability, which depends on the compatibility of polymer chains with solvent molecules and the dissociation of ionic groups in solvents. Compared to non-swellable poly(ionic liquid)s, SPILs have good solvent affinity and distinctive physicochemical properties, making them widely applicable in catalysts, actuators, sensors, absorbents, and separation membranes, among others.
PROGRESS IN POLYMER SCIENCE
(2022)
Article
Environmental Sciences
Humaira Gul Zaman, Lavania Baloo, Shamsul Rahman Kutty, Khalid Aziz, Muhammad Altaf, Aniqa Ashraf, Faissal Aziz
Summary: Heavy metal contamination has become a global issue, necessitating the removal of metals from water bodies. This study introduces a composite material (chitosan-UiO-66-glycidyl methacrylate MOF) with excellent adsorption properties for Pb(II) ions. The Langmuir model fits well with the adsorption data, and the composite demonstrates high thermal stability and recyclability, making it a sustainable adsorbent for metal recovery.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Polymer Science
Katia Bacha, Julien Estager, Sylvie Brassart-Pasco, Catherine Chemotti, Antony E. Fernandes, Jean-Pierre Mbakidi, Magali Deleu, Sandrine Bouquillon
Summary: New dendrimers were synthesized from PPI and PAMAM dendrimers using an efficient acid-base reaction with various phenolic acids, and the syntheses were optimized in both microwave and microfluidic reactors. These dendrimers, which are ionic and hydrophilic, exhibited excellent antioxidant properties and showed cytotoxic effects on fibroblast dermal cells.
Article
Engineering, Chemical
Junshuo Cui, Wenkang Li, Xinlun Song, Zetao Zhang, Haibiao Yu, Weijun Shan, Ying Xiong
Summary: This study presents a method for recovering rhenium by synthesizing chitosan functionalized mesoporous silica composites, which showed high adsorption capacity and regeneration performance.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Marija Gizdavic-Nikolaidis, Julia Moreira Pupe, Luciano Paulino Silva, Dragomir Stanisavljev, Darren Svirskis, Simon Swift
Summary: This study presents a facile and rapid method for the synthesis of PANI and PANI/Ch composites using enhanced microwave synthesis. The morphology and structure of the composites can be fine-tuned by adjusting the synthesis conditions. The PANI/Ch composites exhibit enhanced antibacterial efficacy against both Gram-negative and Gram-positive bacteria compared to pure Chs and PANI samples. This eco-friendly method can serve as an alternative for large-scale industrial production of these polymer composites.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Review
Chemistry, Organic
Qingqing You, Mingjie Liao, Huangdi Feng, Junhai Huang
Summary: The decarboxylation or decarboxylative coupling reactions of carboxylic acids and their derivatives are essential tools for organic synthesis. Microwave-assisted technology, recognized by both industry and academia, has been employed for sustainable organic synthesis. This review focuses on the recent developments in microwave-assisted decarboxylative reactions, including transition-metal-catalyzed and metal-free approaches.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Physical
Yang Zheng, Sven Herbers, Qian Gou, Walther Caminati, Jens-Uwe Grabow
Summary: Besides its typical halogen donor behavior, CF3Cl is shown to reveal a new interaction site with CO2, forming a C-dot-dot-dot-Cl tetrel bond through the Cl equatorial belt. Additionally, a secondary C-dot-dot-dot-O tetrel bond and a F-dot-dot-dot-O halogen bond may also contribute to the relative orientation of the moieties in the complex.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Biochemistry & Molecular Biology
Dana Mustafa, Justin M. Overhulse, Boris A. Kashemirov, Charles E. McKenna
Summary: Phosphonic acids are important organophosphorus compounds widely used in various fields. A convenient and efficient method for the preparation of phosphonic acids is silyldealkylation with bromotrimethylsilane (BTMS), followed by desilylation. We investigated microwave irradiation as an acceleration method for BTMS reactions and found that it had significant advantages over conventional heating, including higher yields and chemoselectivity. This method was also applied to the preparation of antiviral and anticancer drugs, showing great potential.
Article
Chemistry, Multidisciplinary
David M. Williams, Sally B. Morton, L. David Finger, Roxanne van der Sluijs, William D. Mulcrone, Michael Hodskinson, Christopher L. Millington, Christina Vanhinsbergh, Ketan J. Patel, Mark J. Dickman, Puck Knipscheer, Jane A. Grasby
Summary: DNA cross-link (ICLs) can cause lethal events such as cancer or bone marrow failure during replication and transcription. The Fanconi Anemia (FA) pathway proteins are responsible for repairing ICLs, but the details of the pathway are not fully known. Methods to create DNA containing ICLs are crucial for further understanding cross-link repair. A major method to form ICLs in vivo is through DNA reaction with acetaldehyde from ethanol metabolism. This research presents an efficient approach using a novel N2-((R)-4-trifluoroacetamidobutan-2-yl)-2'-deoxyguanosine phosphoramidite for preparing reduced acetaldehyde ICLs. The simplicity, efficiency, and stability of this method will contribute to future studies on cross-link repair.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Sally B. Morton, L. David Finger, Roxanne van der Sluijs, William D. Mulcrone, Michael Hodskinson, Christopher L. Millington, Christina Vanhinsbergh, Ketan J. Patel, Mark J. Dickman, Puck Knipscheer, Jane A. Grasby, David M. Williams
Summary: DNA interstrand cross-links (ICLs) have significant implications for DNA replication and transcription, and understanding their repair is crucial. This study presents an efficient method for generating reduced acetaldehyde ICLs, which can be used to study their recognition and repair. The methodology described here shows promising results and will facilitate further research in cross-link repair.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Engineering, Environmental
Nur Shazwani Abdul Mubarak, N. N. Bahrudin, Ali H. Jawad, B. H. Hameed, S. Sabar
Summary: In this study, sulfonated chitosan montmorillonite composite beads were successfully synthesized using a microwave irradiation method for efficient dye removal. The adsorption of methylene blue onto the composite followed Pseudo-second-order kinetic and Langmuir isotherm model, with a maximum adsorption capacity of 188.2 mg g(-1) at 303 K. Thermodynamic analysis showed that the adsorption reaction was favorable and spontaneous, indicating the potential efficacy of the composite as a biohybrid adsorbent for cationic dyes.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Chemistry, Organic
David E. Q. Jimenez, Lucas L. L. Zanin, Irlon M. M. Ferreira, Victor Deflon, Luan F. F. Diniz, Javier Ellena, Roberto L. A. Haiduke, Andre L. M. Porto
Summary: A green methodology was developed for the synthesis of Knoevenagel adducts using microwave irradiation and under catalyst-free conditions, resulting in high yields. Furthermore, a novel [2+2] photochemical cycloaddition product was discovered and its complex structure was confirmed experimentally.
CURRENT ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Ting-Ting Deng, Yi-Bing Xie, Wen-Wu Sun, Jie Huang, Ting-Ting He, Ji-Kai Liu, Bin Wu
Summary: In this study, a highly efficient method for the synthesis of M1dG and its analogues was developed, which has wide functional group tolerance and provides possibilities for studying DNA damage and repair processes.
Article
Polymer Science
Viktoryia Nikalaichuk, Kseniya Hileuskaya, Aliaksandr Kraskouski, Viktoryia Kulikouskaya, Helen Nedved, Joanna Kalatskaja, Ekaterina Rybinskaya, Kanstantsin Herasimovich, Nikolai Laman, Vladimir Agabekov
Summary: The study showed that there are differences in stability of chitosan-caffeic and chitosan-ferulic acid conjugates in different forms, with freeze-dried conjugates being more stable than freshly synthesized ones. It was also found that freeze-dried conjugates are more stable under UV irradiation and have an influence on the growth of barley seedlings.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Dominik Sikorski, Marta Bauer, Justyna Fraczyk, Zbigniew Draczynski
Summary: This article presents a comparative study on the antibacterial and antifungal activity of chitosan nonwovens modified with various acids. The results showed that chitosan salts with acetic acid and hydrochloric acid exhibited antimicrobial activity. The study also investigated the influence of acid concentration, treatment time, and rinsing process on the antimicrobial activity of the modified materials.
Article
Biotechnology & Applied Microbiology
Vaibhav A. Mantri, M. Ganesan, Vishal Gupta, P. Krishnan, A. K. Siddhanta
JOURNAL OF APPLIED PHYCOLOGY
(2019)
Article
Chemistry, Multidisciplinary
Supratim Chakraborty, Manohara Halanur Mruthunjayappa, Kanakaraj Aruchamy, Nripat Singh, Kamalesh Prasad, Dharmalingam Kalpana, Debasis Ghosh, Nataraj Sanna Kotrappanavar, Dibyendu Mondal
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2019)
Article
Biochemistry & Molecular Biology
Jitkumar Bhatt, Matheus M. Pereira, Kamalesh Prasad
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Chemistry, Multidisciplinary
Jeremy Depoorter, Adeline Mourlevat, Guillaume Sudre, Isabelle Morfin, Kamalesh Prasad, Anatoli Serghei, Julien Bernard, Etienne Fleury, Aurelia Charlot
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2019)
Article
Chemistry, Multidisciplinary
Rosy Alphons Sequeira, Mukesh Sharma, Matheus M. Pereira, Nripat Singh, Sourish Bhattacharya, Nishith A. Chudasama, Kamalesh Prasad
Summary: The study demonstrated the successful separation of ε-PL using the synthesized ionic liquids and polypropylene glycol to form aqueous biphasic systems, achieving extraction efficiency of over 98% while maintaining the chemical and structural stability of ε-PL.
SEPARATION SCIENCE AND TECHNOLOGY
(2021)
Article
Environmental Sciences
Denish Kubavat, Khanjan Trivedi, Pradeep Vaghela, Kamalesh Prasad, Gopalakrishnan K. Vijay Anand, Hardik Trivedi, Rajesh Patidar, Jayesh Chaudhari, Bhoomi Andhariya, Arup Ghosh
LAND DEGRADATION & DEVELOPMENT
(2020)
Article
Chemistry, Multidisciplinary
Rosy Alphons Sequeira, Sonam Dubey, Matheus M. Pereira, Tapan Kumar Maity, Sanju Singh, Sandhya Mishra, Kamalesh Prasad
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2020)
Article
Polymer Science
Sanjay Tiwari, Jayant Sarolia, Vrushti Kansara, Nishith A. Chudasama, Kamalesh Prasad, Debes Ray, Vinod K. Aswal, Pratap Bahadur
Article
Biotechnology & Applied Microbiology
Vaibhav A. Mantri, Yashesh Shah, Nikunj Balar, Keval Chavda, Mayur Mavani, Mayur Kolhe, Kanchan Sambhwani, Ramavatar Meena, Kamlaesh Prasad, Monica G. Kavale, Rajendra Singh Thakur
Summary: This study compared different life cycle stages of the red alga Gracilaria dura, focusing on morphological structures, growth performance, agarose characteristics, biochemical, and molecular profiling. Significant differences were found in growth rates and agarose yield among male gametophytes, tetrasporophytes, and cystocarpic female gametophytes. Metabolomic analysis revealed critical differences in alanine, lactate, and isethionic acid among stages, while genetic correlation analysis showed an average polymorphism of 47.02%. The study concludes that characterizing and differentiating isomorphic life phases of G. dura could be valuable for selecting appropriate cultivars for commercial farming and breeding programs.
JOURNAL OF APPLIED PHYCOLOGY
(2021)
Article
Chemistry, Physical
Gyanendra Sharma, Rosy Alphons Sequeira, Matheus M. Pereira, Tapan Kumar Maity, Nishith A. Chudasama, Kamalesh Prasad
Summary: The study found that ILs are more advantageous than DESs in terms of the dissolution and stability of DNA, mainly due to the higher dissolution capacity and better hydrogen bonding ability with DNA of ILs as compared to DESs.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Multidisciplinary
Jitkumar Bhatt, Rosy Alphons Sequeira, Aliasgar Vohra, Ranjitsinh Vijaysingh Devkar, Tapan Kumar Maity, Kamalesh Prasad
Summary: The sustainable method developed in this study allows for the facile production of nonviral gene vectors using ionic liquids, producing stable nanosized polyplexes that are hemocompatible and noncytotoxic. The one-pot strategy produces no byproducts, maximizing atom economy for bulk production. The single-step process is energy efficient and cost-effective, making it suitable for advanced gene delivery applications.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Chemistry, Applied
Arun Kumar Das, Rosy Alphons Sequeira, Tapan Kumar Maity, Kamalesh Prasad
Summary: Seven different bio-based ionic liquids were investigated for their ability to coagulate kappa-carrageenan, with two showing promising results in terms of polysaccharide extraction yield and properties similar to the conventional method. This coagulation method using bio-based ionic liquids may serve as a suitable alternative for eco-friendly downstream processing of carrageenophytes.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Multidisciplinary
Mukesh Sharma, Ana Paula M. Tavares, Joao C. F. Nunes, Nripat Singh, Dibyendu Mondal, Marcia C. Neves, Kamalesh Prasad, Mara G. Freire
Article
Chemistry, Multidisciplinary
Kamalesh Prasad, Mukesh Sharma
CURRENT OPINION IN GREEN AND SUSTAINABLE CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Nripat Singh, Kamalesh Prasad
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
