Article
Biochemistry & Molecular Biology
Guilherme Ribeiro de Carvalho, Amanda Miki Kudaka, Rafael Affonso Netto, Camila Delarmelina, Marta Cristina Teixeira Duarte, Liliane Maria Ferrareso Lona
Summary: This study developed a polyelectrolyte film with antiviral and antibacterial activity using sodium alginate and poly(diallyldimethylammonium chloride). The film showed continuous and compact structures, and the addition of poly(diallyldimethylammonium chloride) improved its mechanical properties and thermal stability. The polyelectrolyte film exhibited inhibitory effects against SARS-CoV-2, Staphylococcus aureus, and Escherichia coli.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Environmental
Abdullah M. Aldawsari, Hassan M. A. Hassan, Abdulelah Nashmi Alrashidi, Ibrahim Hotan Alsohaimi, Hotan Alsohaimi, Shaima M. N. Moustafa, Hany M. Youssef, Raghda Hamdi, Maged A. Azzam
Summary: This study successfully prepared PVDF-co-PAAm/MGO nanocomposite membrane using a nonsolvent induced phase separation method, which exhibited strong ultrafiltration morphology, improved water flux and rejection, as well as excellent antibacterial activity.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Engineering, Biomedical
Yingchao Su, Jiayin Fu, Juncen Zhou, Elias Georgas, Shaokang Du, Yi-Xian Qin, Yadong Wang, Yufeng Zheng, Donghui Zhu
Summary: Zinc (Zn) is a bioresorbable metal that has potential applications in cardiovascular stent material, orthopedic implants, wound closure devices, etc. However, pure Zn is not ideal for these applications due to its low mechanical strength and localized degradation behavior. This study explores the alloying of Zn with selective transition metals (vanadium-V, chromium-Cr, and zirconium-Zr) to improve its properties. The blended alloys showed improved mechanical strength, suitable degradation rate, and acceptable biocompatibility, making them potential candidates for bioresorbable medical implants.
BIOACTIVE MATERIALS
(2023)
Article
Chemistry, Applied
Yuyi Du, Shikai Zhang, Liangjie Sheng, Hangyu Ma, Fangzhou Xu, Geoffrey I. N. Waterhouse, Dongxiao Sun-Waterhouse, Peng Wu
Summary: This study aims to improve the mechanical properties, hydrophobicity, and antibacterial activities of konjac glucomannan (KGM) films. By incorporating zein-pectin nanoparticle-stabilized corn germ oil-oregano essential oil Pickering emulsion (ZPCEO) into KGM and ionically crosslinking the resulting film with metal ions (Ca2+, Cu2+, or Fe3+), the researchers achieved enhanced water resistance, UV-blocking properties, antioxidant activity, and antimicrobial activity. The ZPCEO/KGM-Fe3+ film showed the best overall performance. This research demonstrates the potential application of ionically crosslinked ZPCEO/KGM films in high humidity food packaging.
Article
Polymer Science
Xiaowei Xu, Jie Pang
Summary: The study introduced SL and ε-PL to fabricate a KGM/SL/ε-PL composite film, significantly enhancing its mechanical strength and antibacterial properties. The composite film showed good inhibitory effect on Escherichia coli and Staphylococcus aureus, indicating its potential for food packaging applications.
Article
Chemistry, Applied
Chenguang Jiang, Yonggang Wang, Haiyong Zhang, Xiongchao Lin, KeChang Xie
Summary: In this study, H beta zeolites and NiMoC/H beta-Mx catalysts were successfully prepared using different molecular weight of PDADMAC as a template. The influence of PDADMAC molecular weight on the catalyst performance and the importance of mesopore diameter and acid sites ratio were studied for aromatics hydrogenation. The NMCH-M3 catalyst with PDADMAC molecular weight of 400,000-500,000 exhibited excellent hydrogenation performance in both model compounds and real oils.
FUEL PROCESSING TECHNOLOGY
(2021)
Article
Polymer Science
Noha G. Madian, Basant A. El-Ashmanty, Hadeel K. Abdel-Rahim
Summary: Chitosan films blended with natural biomaterials such as cellulose, honey, and curcumin were studied to improve their physical properties. Fourier transform infrared spectroscopy, mechanical tensile properties, X-ray diffraction, antibacterial effects, and scanning electron microscopy were investigated. Films blended with curcumin showed higher rigidity, compatibility, and antibacterial effects. Moreover, blending chitosan films with curcumin reduced the crystallinity of the chitosan matrix due to increased intermolecular hydrogen bonding, as observed through X-ray diffraction and scanning electron microscopy.
Article
Nanoscience & Nanotechnology
Ge Zhang, Yuke Li, Qining Ke, Junchen Bai, Fushuai Luo, Jiacheng Zhang, Yanfen Ding, Juan Chen, Peng Liu, Shu Wang, Chong Gao, Mingshu Yang
Summary: In this study, a polymeric antibacterial agent was prepared using the melt grafting method. It was found that the resulting composite material showed high antibacterial activity against E. coli and S. aureus, and the antibacterial effect became more pronounced with the prolongation of chlorinated time.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Fang Wu, Jie Tan, Jin-Hui Wu, Jun-Chi Zhou, Yao Wu
Summary: A bifunctional additive b-PBAUi was synthesized to simultaneously improve the toughness and antibacterial activity of PLLA. Microvoids were found to be the main tensile toughening mechanism for PLLA/b-PBAUi blends. Additionally, the antibacterial activity of PLLA was significantly enhanced by adding b-PBAUi.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Analytical
Quang Khanh Nguyen, Thi Hieu Hoang, Xuan Thanh Bui, Thi Anh Huong Nguyen, Tien Duc Pham, Thi Ngoc Mai Pham
Summary: Positively charged and stable gold nanoparticles were successfully synthesized using HAuCl4 solution and NaBH4, with PDADMAC as stabilizing agent. A colorimetric method for detecting cysteine was developed based on the interaction with gold surfaces, showing high selectivity and precision in real pharmaceutical samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Pia Ramos, Shashank Singh Kalra, Nicholas W. Johnson, Chia Miang Khor, Annesh Borthakur, Brian Cranmer, Gregory Dooley, Sanjay K. Mohanty, David Jassby, Jens Blotevogel, Shaily Mahendra
Summary: The study demonstrates that modifying granular activated carbon (GAC) with cationic polymer poly dia-llyldimethylammonium chloride (polyDADMAC) enhances its adsorption capacity for per- and polyfluoroalkyl substances (PFASs). The modified GAC shows effective adsorption even in the presence of competing ions. Additionally, low-power ultrasound can be used to desorb PFASs from the polyDADMAC-GAC, making it a regenerable adsorbent.
ENVIRONMENTAL POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Wenli Yan, Tao Yin, Shanbai Xiong, Juan You, Yang Hu, Qilin Huang
Summary: The deacetylation degree of konjac glucomannan (KGM) has significant effects on the properties of silver carp surimi gel. With increasing deacetylation degree, viscosity, solubility, water absorption capability, gel strength, water distribution, and microstructure of the surimi gel are all affected. A deacetylation degree of 50.72% is identified as the most suitable for surimi products due to the observed changes in these properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Tien Duc Pham, Viet Phuong Bui, Thuy Nga Pham, Thi Mai Dung Le, Kim Thuy Nguyen, Van Hoi Bui, The Dung Nguyen
Summary: This study demonstrated the effective adsorption of anionic azo dye NCC on PDADMAC modified silica and silica-gel in an aquatic environment. The removal efficiencies of NCC using PMS and PMSG were higher than 87%, indicating their potential as novel and reusable adsorbents for anionic dye removal. The electrostatic interaction between positively charged adsorbents' surfaces and negative sulfonic groups of NCC was identified as the main driving force for anionic azo dye adsorption onto PMS and PMGS adsorbents through analysis of adsorption isotherms and surface group changes.
Article
Materials Science, Paper & Wood
Yujiao Wu, Fan Wang, Yuyan Wu, Bo Yan, Qinchuan Li
Summary: In this study, a high-performance and high-durability ionic electroactive polymer actuator was introduced for developing active components in micrototal analysis systems and microelectromechanical systems. The actuator was fabricated by hot pressing a novel ionic actuator with a free-standing bacterial cellulose reinforced polyelectrolyte membrane sandwiched between two free-standing conductive polymer membranes. The addition of bacterial cellulose resulted in high mechanical properties of the polyelectrolyte membrane. The resulting actuator exhibited excellent actuation performances, high reproducibility, stability, and durability, and showed potential biomimetic applications in microsystems.
Article
Engineering, Environmental
N. R. H. Rao, A. M. Granville, R. K. Henderson
Summary: The study tested a novel modified-bubble DAF process with biomolecular additives, finding that proteins and carbohydrates play a crucial role in cell separation. Enhanced separation of up to 79% was achieved by simultaneously dosing high MW and high charge protein- and carbohydrate additives, forming protein-carbohydrate-cell suprastructures. This suggests that interactions between proteins, carbohydrates, and cells are essential for improving cell separation in the presence of a flocculant like PDADMAC.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)