Arecoline downregulates levels of p21 and p27 through the reactive oxygen species/mTOR complex 1 pathway and may contribute to oral squamous cell carcinoma

Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines

(2011) Masako Abe et al.   BMC CANCER

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Eukaryotic elongation factor-2 (eEF2): its regulation and peptide chain elongation

(2011) Gautam Kaul et al.   CELL BIOCHEMISTRY AND FUNCTION

Cytotoxic Effects Produced by Arecoline Correlated to Epigenetic Regulation in Human K-562 Cells

(2011) Pei-Chin Lin et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Levels of p27 Sensitize to Dual PI3K/mTOR Inhibition

(2011) M. Lee et al.   MOLECULAR CANCER THERAPEUTICS

α-Catulin knockdown induces senescence in cancer cells

(2011) L-C Fan et al.   ONCOGENE

Arecoline-mediated inhibition of AMP-activated protein kinase through reactive oxygen species is required for apoptosis induction

(2011) Ching-Yu Yen et al.   ORAL ONCOLOGY

Areca nut extract induced oxidative stress and upregulated hypoxia inducing factor leading to autophagy in oral cancer cells

(2010) Hsuan-Hsuan Lu et al.   Autophagy

Hemeoxygenase-1 expression in response to arecoline-induced oxidative stress in human umbilical vein endothelial cells

(2010) Thu-Ching Hung et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Salivary arecoline levels during areca nut chewing in human volunteers

(2010) Stephen Cox et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Decreased GRP78 Protein Expression is a Potential Prognostic Marker of Oral Squamous Cell Carcinoma in Taiwan

(2010) Tze-Ta Huang et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis

(2010) Yu-Chu Wang et al.   ORAL ONCOLOGY

Autophagy induction by the 30–100kDa fraction of areca nut in both normal and malignant cells through reactive oxygen species

(2010) Mei-Huei Lin et al.   ORAL ONCOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Interfering with ROS Metabolism in Cancer Cells: The Potential Role of Quercetin

(2010) Lara Gibellini et al.   Cancers

p27Kip1 Stabilization Is Essential for the Maintenance of Cell Cycle Arrest in Response to DNA Damage

(2009) M. Cuadrado et al.   CANCER RESEARCH

A Prostatic Intraepithelial Neoplasia-Dependent p27Kip1 Checkpoint Induces Senescence and Inhibits Cell Proliferation and Cancer Progression

(2008) Pradip K. Majumder et al.   CANCER CELL

mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

(2008) Feng Hong et al.   MOLECULAR CELL

Arecoline, a major alkaloid of areca nut, inhibits p53, represses DNA repair, and triggers DNA damage response in human epithelial cells

(2008) Yi-Shan Tsai et al.   TOXICOLOGY

Cell Density and Serum Exposure Modify the Function of the Glucocorticoid Receptor C/EBP Complex

(2007) Jing-Qing Yang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Molecular mechanisms of p21 and p27 induction by 3-methylcholanthrene, an aryl-hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells

(2007) Pai-Huei Pang et al.   JOURNAL OF CELLULAR PHYSIOLOGY