Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex

The Hsp90 chaperone machinery: from structure to drug development

(2011) Ji-Sook Hahn   BMB Reports

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes

(2010) H. Takai et al.   GENES & DEVELOPMENT

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

(2010) K. E. Hurov et al.   GENES & DEVELOPMENT

The Pih1-Tah1 Cochaperone Complex Inhibits Hsp90 Molecular Chaperone ATPase Activity

(2010) Kelvin Eckert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly

(2010) Takeshi Kaizuka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability

(2010) Zuzana Hořejší et al.   MOLECULAR CELL

HSP90 and Its R2TP/Prefoldin-like Cochaperone Are Involved in the Cytoplasmic Assembly of RNA Polymerase II

(2010) Séverine Boulon et al.   MOLECULAR CELL

Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

(2010) Fernando Pastor et al.   NATURE

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AAA+ Proteins RUVBL1 and RUVBL2 Coordinate PIKK Activity and Function in Nonsense-Mediated mRNA Decay

(2010) N. Izumi et al.   Science Signaling

SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay

(2009) A. Yamashita et al.   GENES & DEVELOPMENT

Hsp90 inhibitors as promising agents for radiotherapy

(2009) Alexander E. Kabakov et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

RVB1/RVB2: Running Rings around Molecular Biology

(2009) Sudhakar Jha et al.   MOLECULAR CELL

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chaperone ligand-discrimination by the TPR-domain protein Tah1

(2008) Stefan H. Millson et al.   BIOCHEMICAL JOURNAL

ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function

(2008) N. B. Collins et al.   BLOOD

Silencing of HSP90 Cochaperone AHA1 Expression Decreases Client Protein Activation and Increases Cellular Sensitivity to the HSP90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin

(2008) J. L. Holmes et al.   CANCER RESEARCH

Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly

(2008) Andrew S. Venteicher et al.   CELL

Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break

(2008) C. M. Anderson et al.   GENES & DEVELOPMENT

HCLK2 Is Required for Activity of the DNA Damage Response Kinase ATR

(2008) Jannie M. Rendtlew Danielsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hsp90 Chaperone Machinery

(2008) Sebastian Karl Wandinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

(2008) Séverine Boulon et al.   JOURNAL OF CELL BIOLOGY

Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

(2008) Rongmin Zhao et al.   JOURNAL OF CELL BIOLOGY

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

(2008) Martin F. Lavin   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nonsense-Mediated mRNA Decay Impacts MSI-Driven Carcinogenesis and Anti-Tumor Immunity in Colorectal Cancers

(2008) Jamila El-Bchiri et al.   PLoS One