The Hsp90 chaperone machinery: from structure to drug development

Identification of new Hsp90 inhibitors by structure-based virtual screening

(2009) Tae-Joon Hong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Hsp90 mosaic: a picture emerges

(2009) Matthias P Mayer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90

(2009) Martin Hessling et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Specific Arabidopsis HSP90.2 alleles recapitulate RAR1 cochaperone function in plant NB-LRR disease resistance protein regulation

(2009) D. A. Hubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HSP90-SGT1 Chaperone Complex for NLR Immune Sensors

(2008) Ken Shirasu   Annual Review of Plant Biology

The Hsp90 molecular chaperone: an open and shut case for treatment

(2008) Laurence H. Pearl et al.   BIOCHEMICAL JOURNAL

Incapacitating the evolutionary capacitor: Hsp90 modulation of disease

(2008) Patricia L. Yeyati et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

NLR, the nucleotide-binding domain leucine-rich repeat containing gene family

(2008) Zhengmao Ye et al.   CURRENT OPINION IN IMMUNOLOGY

Targeting Hsp90: small-molecule inhibitors and their clinical development

(2008) Tony Taldone et al.   CURRENT OPINION IN PHARMACOLOGY

Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes

(2008) Minghao Zhang et al.   EMBO JOURNAL

Structural and functional analysis of SGT1–HSP90 core complex required for innate immunity in plants

(2008) Yasuhiro Kadota et al.   EMBO REPORTS

The mammalian CHORD-containing protein melusin is a stress response protein interacting with Hsp90 and Sgt1

(2008) Mauro Sbroggiò et al.   FEBS LETTERS

Function of Nod-like receptors in microbial recognition and host defense

(2008) Luigi Franchi et al.   IMMUNOLOGICAL REVIEWS

The Hsp90 Chaperone Machinery Regulates Signaling by Modulating Ligand Binding Clefts

(2008) William B. Pratt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hsp90 Chaperone Machinery

(2008) Sebastian Karl Wandinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unc45 Activates Hsp90-dependent Folding of the Myosin Motor Domain

(2008) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

(2008) Séverine Boulon et al.   JOURNAL OF CELL BIOLOGY

Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

(2008) Rongmin Zhao et al.   JOURNAL OF CELL BIOLOGY

Hsp90-Dependent Activation of Protein Kinases Is Regulated by Chaperone-Targeted Dephosphorylation of Cdc37

(2008) Cara K. Vaughan et al.   MOLECULAR CELL