Effects of fibroblast growth factor 21 on the heart

FGF21 attenuates pathological myocardial remodeling following myocardial infarction through the adiponectin-dependent mechanism

(2015) Yusuke Joki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Serum fibroblast growth factor 21 levels is associated with lower extremity atherosclerotic disease in Chinese female diabetic patients

(2015) Xiaoyan Zhang et al.   Cardiovascular Diabetology

Serum fibroblast growth factor 21 levels are increased in atrial fibrillation patients

(2015) Xinyuan Han et al.   CYTOKINE

Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway

(2015) Chi Zhang et al.   DIABETOLOGIA

FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation

(2015) Xiaoqing Yan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Fibroblast growth factor (FGF21) protects mouse liver against d-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways

(2015) Yinhang Yu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Fibroblast growth factor 21 protects the heart from oxidative stress

(2014) Anna Planavila et al.   CARDIOVASCULAR RESEARCH

The relationship of fibroblast growth factor 21 with cardiovascular outcome events in the Fenofibrate Intervention and Event Lowering in Diabetes study

(2014) Kwok-Leung Ong et al.   DIABETOLOGIA

Possible role of fibroblast growth factor 21 on atherosclerosis via amelioration of endoplasmic reticulum stress-mediated apoptosis in apoE−/− mice

(2014) Xi Wu et al.   HEART AND VESSELS

Novel Insights into the Cardio-Protective Effects of FGF21 in Lean and Obese Rat Hearts

(2014) Vanlata Patel et al.   PLoS One

Serum Fibroblast Growth Factor-21 Levels Are Associated With Carotid Atherosclerosis Independent of Established Cardiovascular Risk Factors

(2013) Wing Sun Chow et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteomic study on the protective mechanism of fibroblast growth factor 21 to ischemia–reperfusion injury

(2013) Wei-Tao Cong et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Additive relationship between serum fibroblast growth factor 21 level and coronary artery disease

(2013) Yun Shen et al.   Cardiovascular Diabetology

Serum fibroblast growth factor 21 is predictive of combined cardiovascular morbidity and mortality in patients with type 2 diabetes at a relatively short-term follow-up

(2013) M. Lenart-Lipińska et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Exploring mechanisms of FGF signalling through the lens of structural biology

(2013) Regina Goetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fibroblast growth factor 21 protects against cardiac hypertrophy in mice

(2013) A. Planavila et al.   Nature Communications

Endocrine Protection of Ischemic Myocardium by FGF21 from the Liver and Adipose Tissue

(2013) Shu Q. Liu et al.   Scientific Reports

Pathophysiological roles of FGF signaling in the heart

(2013) Nobuyuki Itoh et al.   Frontiers in Physiology

Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia

(2012) Shu Q. Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

(2012) Xunshan Ding et al.   Cell Metabolism

Serum FGF21 concentration is associated with hypertriglyceridaemia, hyperinsulinaemia and pericardial fat accumulation, independently of obesity, but not with current coronary artery status

(2012) Yenna Lee et al.   CLINICAL ENDOCRINOLOGY

Lack of Overt FGF21 Resistance in Two Mouse Models of Obesity and Insulin Resistance

(2011) Clarence Hale et al.   ENDOCRINOLOGY

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

(2011) N. Itoh et al.   JOURNAL OF BIOCHEMISTRY

Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone

(2011) Wasana Pratchayasakul et al.   LIFE SCIENCES

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

(2010) f. M. Fisher et al.   DIABETES

Serum Levels of FGF-21 Are Increased in Coronary Heart Disease Patients and Are Independently Associated with Adverse Lipid Profile

(2010) Zhuofeng Lin et al.   PLoS One

FGFs and metabolism

(2009) Alexei Kharitonenkov   CURRENT OPINION IN PHARMACOLOGY

Fibroblast Growth Factor 21-Deficient Mice Demonstrate Impaired Adaptation to Ketosis

(2009) Michael K. Badman et al.   ENDOCRINOLOGY

Fibroblast Growth Factor 21 Regulates Lipolysis in White Adipose Tissue But Is Not Required for Ketogenesis and Triglyceride Clearance in Liver

(2009) Yuhei Hotta et al.   ENDOCRINOLOGY

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

FGF21 induces PGC-1  and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

(2009) M. J. Potthoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FGF21 N- and C-termini play different roles in receptor interaction and activation

(2008) Junming Yie et al.   FEBS LETTERS

βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3c

(2008) Masashi Suzuki et al.   MOLECULAR ENDOCRINOLOGY

FGF-21/FGF-21 receptor interaction and activation is determined by βKlotho

(2007) Alexei Kharitonenkov et al.   JOURNAL OF CELLULAR PHYSIOLOGY