Article
Chemistry, Analytical
Ya Li, Zhiling Liu, Wenbo Lu, Man Zhao, He Xiao, Tianjun Hu, Jianchun Ma, Zhanfeng Zheng, Jianfeng Jia, Haishun Wu
Summary: The novel core-shell nanoarchitecture consisting of Cu-based metal-organic frameworks (Cu-MOFs) and covalent organic frameworks (TpBD-COFs) can be used to prepare an aptasensor for the detection of platelet-derived growth factor-BB (PDGF-BB), achieving sensitive and selective detection of specific biomarkers.
Article
Biotechnology & Applied Microbiology
Xiuxia Wei, Yiwei Sun, Yuting Luo, Ruxin Shu, Huaqing Lin, Dongpo Xu
Summary: The widespread use of antibiotics can lead to residues in the environment and food, which in turn affects health problems. Therefore, it is crucial to detect antibiotic residues. In this study, an efficient and sensitive AMP electrochemical ensemble sensor was successfully prepared, and by optimizing the experimental conditions, AMP can be detected in real samples.
BIOCHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Yujie Han, Xujie Su, Lifang Fan, Zhiguang Liu, Yujing Guo
Summary: In this study, an electrochemical aptasensor was developed for the detection of cTnI using CuNWs/MoS2/rGO structure, showing excellent detection performance with a wide linear range and low detection limit. The sensor demonstrated good selectivity, stability, and reproducibility, making it applicable for cTnI analysis in human blood samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Kaiwen Li, Zhuo Shi, Yuwei Wang, Feng Yan, Zhanhong Li, Zifeng Wang, Zhigang Zhu
Summary: This study developed a label-free electrochemical aptasensor using Ti3C2Tx-Ag/Au NPs for CRP detection. The sensor showed a dual-amplified signal strategy and excellent detection performance, with great potential for clinical diagnostic applications.
MICROCHEMICAL JOURNAL
(2023)
Article
Electrochemistry
Miao Liu, Bingchen Pan, Shanshan Tang, Wei Wang, Huipeng Hou, Bingteng Xie, Axin Liang, Aiqin Luo
Summary: A label-free molecularly imprinted electrochemical sensor (MIECS) based on MXene@AuNPs was developed for the determination of homocysteine (Hcy) in serum. The sensor showed high sensitivity with a linear response in the detection range and favorable selectivity, stability, reproducibility, and ruggedness. It has potential applications in disease surveillance.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Electrochemistry
Yan Wang, Chengju Gong, Yan Zhu, Qianqian Wang, Liping Geng
Summary: A novel electroactive material CQDs-WS2 was prepared and used in a label-free electrochemical aptasensing strategy for sensitive determination of SMZ. The sensor showed wide linear response range from 10 pM to 1.0 pM and a low detection limit of 4.0 mu M, making it suitable for quantitation analysis of antibiotic residue in food and environmental samples.
ELECTROCHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Ya-Shin Yeh, Yi-Kuang Yen, Ragurethinam Shanmugam
Summary: This study developed a cost-efficient, disposable, and highly sensitive paper-based electrochemical biosensor that can detect the concentration of interferon-gamma (IFN-?), which is related to Tuberculosis. It has the potential to assist in disease diagnosis.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Yanling Zhang, Min Liu, Shuai Pan, Lulu Yu, Shaoshuai Zhang, Ruijiang Liu
Summary: In this study, a label-free electrochemical aptasensor was developed using magnetic Fe3O4/Fe2O3@Au nanoparticles as a signal amplifier for the detection of VEGF(165). The aptasensor showed excellent linear relationship and low detection limits, indicating its potential as an efficient and cost-effective method for early screening of VEGF(165)-related diseases.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Applied
Tingting Zhong, Shanshan Li, Xin Li, Yishang JiYe, Yuanyuan Mo, Liying Chen, Zhiqing Zhang, Hejun Wu, Meiliang Li, Qingying Luo
Summary: An electrochemical aptasensor was fabricated for sensitive detection of AFB1 using a modified ZIF-8. The developed aptasensor exhibited a wider linear range and lower detection limit, as well as outstanding selectivity, reproducibility and stability. The method successfully detected AFB1 in corn oil and peanut oil samples, demonstrating its potential application value.
Article
Chemistry, Analytical
Yingying Wang, Huixin Wang, Yaliang Bai, Guanhui Zhao, Nuo Zhang, Yong Zhang, Yaoguang Wang, Hong Chi
Summary: In this study, an electrochemical immunoassay method based on molybdenum disulfide (MoS2) was proposed to detect neuron-specific enolase (NSE) sensitively. The MoS2@Au nanozyme, formed by composite MoS2 and Au nanoclusters (Au NCs), was used to catalyze the decomposition of H2O2, which amplified the amperometric response and improved sensitivity. The detection range of this strategy was 0.1 pg·mL(-1)-10 ng·mL(-1) with a limit of detection of 0.05 pg·mL(-1). This sensing strategy showed potential for sensitive detection of NSE and can provide a theoretical basis and technical support for detecting other disease markers.
Article
Chemistry, Analytical
Meijuan Du, Qian Chen, Xueqin Xu
Summary: A novel label-free electrochemical aptasensor was developed to detect metronidazole with high sensitivity and selectivity, and it was successfully applied in the detection of metronidazole in tap water and honey samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Applied
Ghazal Behjati Asl, Majid Arvand, Maryam Farahmand Habibi
Summary: Aflatoxin B-1 is a potent liver toxin that poses high hazards to human health by easily accumulating in food and the environment through the food chain. A photo-electrochemical aptasensor can be used for rapid and simple detection of aflatoxin B-1, with excellent reusability, storage stability, reproducibility, and specificity.
Article
Materials Science, Multidisciplinary
Ming Yin, Li Zhang, Yan Chen, Shuyan Qi, Xiuxia Wei, Xinxin Tian, Jingxuan Qiu, Dongpo Xu
Summary: A mesoporous In2O3@Au nanofiber was proposed as an electrochemical aptasensor for the detection of ampicillin. The sensor exhibited good selectivity and cycle stability, and it could effectively and sensitively detect ampicillin in milk.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Analytical
Kaicha Chen, Hongli Zhao, Zhenxing Wang, Fangfang Zhou, Minbo Lan
Summary: A sandwich-type electrochemical aptasensor was constructed for the simultaneous detection of cardiac troponin I (cTnI) and myoglobin (Myo). The aptasensor demonstrated excellent performance in clinical diagnosis of acute myocardial infarction. The results showed wide linear ranges and low detection limits, indicating the potential application of the aptasensor.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Agriculture, Multidisciplinary
Xiaobo Zhang, Zhiru Li, Lin Hong, Xiuwen Wang, Jijuan Cao
Summary: In this study, a paper-based electrochemical aptasensor was designed, utilizing TDNs technology to improve the recognition efficiency of the aptamer towards FB1. The aptasensor showed sensitivity and reliability in the analysis of FB1 at low concentrations, demonstrating its great potential in food safety and public health.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Analytical
Gang Qu, Yuxin Zhao, Qiaoli Zhang, Jina Wu, Xiaosen Li, Yang Yang, Shilei Liu
Summary: In this study, magnetic mesoporous materials combined with real-time in situ mass spectrometry were used for the high-throughput detection of hydrolyzed products of organophosphorus nerve agents. The method showed good linearity, low limits of detection and quantification, and high extraction recoveries. The magnetic preparation method used was quick, cost-effective, rugged, and safe. The results demonstrated the potential of this method for rapid and efficient determination of the target analytes in environmental samples.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Anna Hildebrand, Mariam Merchant, Danny O'Hare
Summary: Substandard and falsified artemisinin derivatives in antimalarials have caused significant deaths and economic losses. This study evaluates the feasibility of voltammetric methods for identifying and quantifying artemether. The findings suggest that electrochemical analysis shows promise as a method for artemether identification and quantification.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Marx Osorio Araujo Pereira, Alvaro Ferreira Junior, Edson Silvio Batista Rodrigues, Helena Mulser, Giovanna Nascimento de Mello e Silva, Wallans Torres Pio dos Santos, Eric de Souza Gil
Summary: Brazilian spotted fever (BSF) is a serious and rapidly evolving disease. A new impedimetric immunosensor was developed for rapid diagnosis by measuring specific antibodies in plasma. The sensor demonstrated selectivity and accuracy, and has potential for important applications in diagnostic testing.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Kathrin Schilling, Ronald A. Glabonjat, Olgica Balac, Marta Galvez-Fernandez, Arce Domingo-Relloso, Vesna Slavkovich, Jeff Goldsmith, Miranda R. Jones, Tiffany R. Sanchez, Ana Navas-Acien
Summary: Analysis of trace elements in urine is an important tool for assessing exposures, diagnosing nutritional status, and guiding public health and healthcare intervention. This study provides a sensitive method for analyzing 18 elements in urine samples, using only 100 μL. The results show good accuracy and sensitivity of the method.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Mengya Li, Shijie Liu, Shiliang Guo, Dong Liang, Miaoyun Li, Yaodi Zhu, Lijun Zhao, Jong-Hoon Lee, Gaiming Zhao, Yangyang Ma, Yanxia Liu
Summary: In this study, a magnetic flow device was developed to purify spores in a culture medium system. The device used magnetic nanoparticles to absorb vegetative cells, separating them from the spores. The achieved purity of the collected spores was over 95%. The study also demonstrated a rapid quantitative detection method using Raman spectroscopy.
ANALYTICAL METHODS
(2024)
Article
Chemistry, Analytical
Wanqiong Liu, Zixuan Wu, Jianwei Peng, Zebin Xu, Yong Liang
Summary: Metal-organic frameworks (MOFs) are effective carriers for molecular imprinting, but their poor dispersibility in aqueous solution is a significant drawback. In this study, we have applied amphiphilic block copolymers and molecularly imprinted technology on MOFs to improve the hydrophilicity of molecularly imprinted fluorescent materials.
ANALYTICAL METHODS
(2024)