Combination of an agonistic anti-CD40 monoclonal antibody and the COX-2 inhibitor celecoxib induces anti-glioma effects by promotion of type-1 immunity in myeloid cells and T-cells

Inhibition of STAT3 Promotes the Efficacy of Adoptive Transfer Therapy Using Type-1 CTLs by Modulation of the Immunological Microenvironment in a Murine Intracranial Glioma

(2014) M. Fujita et al.   JOURNAL OF IMMUNOLOGY

Chemokine (C–X–C motif) ligand (CXCL)10 in autoimmune diseases

(2013) Alessandro Antonelli et al.   AUTOIMMUNITY REVIEWS

CD40 immunotherapy for pancreatic cancer

(2013) Robert H. Vonderheide et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid-derived suppressor cells in cancer: recent progress and prospects

(2013) Yazan S Khaled et al.   IMMUNOLOGY AND CELL BIOLOGY

Profound Impairment of Adaptive Immune Responses by Alkylating Chemotherapy

(2013) A. J. Litterman et al.   JOURNAL OF IMMUNOLOGY

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010

(2013) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Vaccine Injection Site Matters: Qualitative and Quantitative Defects in CD8 T Cells Primed as a Function of Proximity to the Tumor in a Murine Glioma Model

(2012) J. R. Ohlfest et al.   JOURNAL OF IMMUNOLOGY

Differentiation and gene expression profile of tumor-associated macrophages

(2012) Astrid Schmieder et al.   SEMINARS IN CANCER BIOLOGY

COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells

(2011) M. Fujita et al.   CANCER RESEARCH

Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment

(2011) P. Allavena et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Aberrant PGE2 metabolism in bladder tumor microenvironment promotes immunosuppressive phenotype of tumor-infiltrating myeloid cells

(2011) Evgeniy Eruslanov et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

(2011) G. L. Beatty et al.   SCIENCE

COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function

(2010) Joris D Veltman et al.   BMC CANCER

CD40 is a regulator for vascular endothelial growth factor in the tumor microenvironment of glioma

(2010) Fang Xie et al.   JOURNAL OF NEUROIMMUNOLOGY

Arginase: an emerging key player in the mammalian immune system

(2009) Markus Munder   BRITISH JOURNAL OF PHARMACOLOGY

De novo Induction of Genetically Engineered Brain Tumors in Mice Using Plasmid DNA

(2009) S. M. Wiesner et al.   CANCER RESEARCH

Effective Immunotherapy against Murine Gliomas Using Type 1 Polarizing Dendritic Cells—Significant Roles of CXCL10

(2009) Mitsugu Fujita et al.   CANCER RESEARCH

Altered Expression of 15-Hydroxyprostaglandin Dehydrogenase in Tumor-Infiltrated CD11b Myeloid Cells: A Mechanism for Immune Evasion in Cancer

(2009) E. Eruslanov et al.   JOURNAL OF IMMUNOLOGY

Improved therapeutic efficacy using vaccination with glioma lysate-pulsed dendritic cells combined with IP-10 in murine glioma

(2009) Xiao-bing Jiang et al.   VACCINE

TNF-α and the IFN-γ-inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act in synergy to induce antitumor effects in mouse glioblastoma

(2008) M Enderlin et al.   CANCER GENE THERAPY

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

(2008) Naoki Umemura et al.   JOURNAL OF LEUKOCYTE BIOLOGY