Intravenous administration of adenoviruses targeting transforming growth factor beta signaling inhibits established bone metastases in 4T1 mouse mammary tumor model in an immunocompetent syngeneic host

The role of antiresorptive therapies in improving patient care in early and metastatic breast cancer

(2011) Dulcinea Candelaria-Quintana et al.   BREAST CANCER RESEARCH AND TREATMENT

TGFβ-dependent induction of interleukin-11 and interleukin-8 involves SMAD and p38 MAPK pathways in breast tumor models with varied bone metastases potential

(2011) Janhavi Gupta et al.   CANCER BIOLOGY & THERAPY

Adenoviral Vector Immunity: Its Implications and Circumvention Strategies

(2011) Yadvinder S. Ahi et al.   CURRENT GENE THERAPY

Systemic Delivery of a Novel Liver-Detargeted Oncolytic Adenovirus Causes Reduced Liver Toxicity but Maintains the Antitumor Response in a Breast Cancer Bone Metastasis Model

(2011) Zhenwei Zhang et al.   HUMAN GENE THERAPY

Oncolytic Adenovirus Expressing Soluble TGFβ Receptor II-Fc-mediated Inhibition of Established Bone Metastases: A Safe and Effective Systemic Therapeutic Approach for Breast Cancer

(2011) Zebin Hu et al.   MOLECULAR THERAPY

TGF-β in cancer and bone: Implications for treatment of bone metastases

(2010) Patricia Juárez et al.   BONE

Biology of breast cancer bone metastasis

(2010) Mojtaba Akhtari et al.   CANCER BIOLOGY & THERAPY

Oncolytic (replication-competent) adenoviruses as anticancer agents

(2010) Karoly Toth et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Systemic Delivery of an Oncolytic Adenovirus Expressing Soluble Transforming Growth Factor-β Receptor II–Fc Fusion Protein Can Inhibit Breast Cancer Bone Metastasis in a Mouse Model

(2010) Zebin Hu et al.   HUMAN GENE THERAPY

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

A modified hTERT promoter-directed oncolytic adenovirus replication with concurrent inhibition of TGFβ signaling for breast cancer therapy

(2009) Z Hu et al.   CANCER GENE THERAPY

Targeting the transforming growth factor-β signaling pathway in human cancer

(2009) Nagathihalli S Nagaraj et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors

(2009) John Nemunaitis et al.   MOLECULAR THERAPY

Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis

(2009) Manav Korpal et al.   NATURE MEDICINE

Transforming Growth Factor   Subverts the Immune System into Directly Promoting Tumor Growth through Interleukin-17

(2008) J.-S. Nam et al.   CANCER RESEARCH

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Roles of TGFβ in metastasis

(2008) David Padua et al.   CELL RESEARCH

Immunosuppression Enhances Oncolytic Adenovirus Replication and Antitumor Efficacy in the Syrian Hamster Model

(2008) Maria A Thomas et al.   MOLECULAR THERAPY