Article
Nutrition & Dietetics
Raul Zamora-Ros, Leila Lujan-Barroso, David Achaintre, Silvia Franceschi, Cecilie Kyro, Kim Overvad, Anne Tjonneland, Therese Truong, Lucie Lecuyer, Marie-Christine Boutron-Ruault, Verena Katzke, Theron S. Johnson, Matthias B. Schulze, Antonia Trichopoulou, Eleni Peppa, Carlo La Vechia, Giovanna Masala, Valeria Pala, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Guri Skeie, J. Ramon Quiros, Miguel Rodriguez-Barranco, Pilar Amiano, Maria-Dolores Chirlaque, Eva Ardanaz, Martin Almquist, Joakim Hennings, Roel Vermeulen, Nicholas J. Wareham, Tammy Y. N. Tong, Dagfinn Aune, Graham Byrnes, Elisabete Weiderpass, Augustin Scalbert, Sabina Rinaldi, Antonio Agudo
Summary: This study found that caffeic acid and its dehydrogenated metabolite, 3,4-dihydroxyphenylpropionic acid, were inversely associated with differentiated thyroid cancer risk, particularly with papillary thyroid cancer, but these associations were not significant after Bonferroni correction for multiple testing. High blood concentrations of caffeic, 3,4-dihydroxyphenylpropionic, and ferulic acids may potentially be related to a lower risk of papillary thyroid cancer, but overall, blood polyphenol concentrations were mostly not associated with differentiated thyroid cancer risk in women.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Lucie Lecuyer, Nasser Laouali, Laure Dossus, Nitin Shivappa, James R. Hebert, Antonio Agudo, Anne Tjonneland, Jytte Halkjaer, Kim Overvad, Verena A. Katzke, Charlotte Le Cornet, Matthias B. Schulze, Franziska Jannasch, Domenico Palli, Claudia Agnoli, Rosario Tumino, Luca Dragna, Gabriella Iannuzzo, Torill Enget Jensen, Magritt Brustad, Guri Skeie, Raul Zamora-Ros, Miguel Rodriguez-Barranco, Pilar Amiano, Maria-Dolores Chirlaque, Eva Ardanaz, Martin Almquist, Emily Sonestedt, Maria Sandstrom, Lena Maria Nilsson, Elisabete Weiderpass, Inge Huybrechts, Sabina Rinaldi, Marie-Christine Boutron-Ruault, Therese Truong
Summary: This study investigates the association between diet and thyroid cancer risk. The results suggest that diet-associated inflammation is weakly positively associated with the risk of thyroid cancer in European adults, and further validation is needed in independent studies.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Oncology
Nathalie Kliemann, Romain Ould Ammar, Carine Biessy, Audrey Gicquiau, Verena Katzke, Rudolf Kaaks, Anne Tjonneland, Anja Olsen, Maria-Jose Sanchez, Marta Crous-Bou, Fabrizio Pasanisi, Sandar Tin Tin, Aurora Perez-Cornago, Dagfinn Aune, Sofia Christakoudi, Alicia K. Heath, Sandra M. Colorado-Yohar, Sara Grioni, Guri Skeie, Hanna Sartor, Annika Idahl, Charlotta Rylander, Anne M. May, Elisabete Weiderpass, Heinz Freisling, Mary C. Playdon, Sabina Rinaldi, Neil Murphy, Inge Huybrechts, Laure Dossus, Marc J. Gunter
Summary: Metabolic dysfunction is associated with higher risk of endometrial cancer in women, regardless of their body size. Obesity increases the risk of endometrial cancer, even among women with lower insulin levels. Classifying women by metabolic health may be more effective in identifying those at higher risk for endometrial cancer than solely relying on anthropometry.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Endocrinology & Metabolism
Junyu Zhao, Yutian Tian, Zhen Jia, Jinming Yao, Lin Liao, Jianjun Dong
Summary: The study found that abnormal glucose metabolism parameters, such as diabetes mellitus, hyperinsulinemia, and insulin resistance, are significantly associated with the carcinogenesis and aggressiveness of differentiated thyroid carcinoma (DTC). More DTC patients exhibited multifocality, extra-glandular invasion, and lymph node metastasis.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Tiberiu A. Pana, Mamas A. Mamas, Nicholas J. Wareham, Kay-Tee Khaw, Dana K. Dawson, Phyo K. Myint
Summary: This study aims to understand the sex-specific lifetime trajectories of different heart and circulatory disorders and their relationship with death from heart disease. The results of the study show that men have a higher lifetime risk of heart and circulatory disorders compared with women. Men are more likely to experience myocardial infarction as the first manifestation, while women are more likely to develop atrial fibrillation and stroke after a certain age. The excess risk of death from heart disease observed in men with pre-existing heart disease is attenuated compared with those free of heart disease at baseline. In conclusion, our study highlights the marked sex disparities in heart disease and death over the very long-term, emphasizing the need for tailored heart disease prevention efforts for both men and women.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Wenqing Zhang, Xiaoquan Feng, Yan Zhou, Jing-Huo Chen, Seik Weng Ng, Guang Yang
Summary: Four silver(I) pyrazolato complexes were synthesized and characterized, and their structural transformations were investigated through experimental and theoretical analyses. The study provides insights into the solvent-assisted, acid-base interaction promoted, and thermodynamically favored process of isomeric transformation.
CRYSTAL GROWTH & DESIGN
(2022)
Article
Medicine, General & Internal
Marie Breeur, Pietro Ferrari, Laure Dossus, Mazda Jenab, Mattias Johansson, Sabina Rinaldi, Ruth C. Travis, Mathilde His, Tim J. Key, Julie A. Schmidt, Kim Overvad, Anne Tjonneland, Cecilie Kyro, Joseph A. Rothwell, Nasser Laouali, Gianluca Severi, Rudolf Kaaks, Verena Katzke, Matthias B. Schulze, Fabian Eichelmann, Domenico Palli, Sara Grioni, Salvatore Panico, Rosario Tumino, Carlotta Sacerdote, Bas Bueno-de-Mesquita, Karina Standahl Olsen, Torkjel Manning Sandanger, Therese Haugdahl Nost, J. Ramon Quiros, Catalina Bonet, Miguel Rodriguez Barranco, Maria-Dolores Chirlaque, Eva Ardanaz, Malte Sandsveden, Jonas Manjer, Linda Vidman, Matilda Rentoft, David Muller, Kostas Tsilidis, Alicia K. Heath, Hector Keun, Jerzy Adamski, Pekka Keski-Rahkonen, Augustin Scalbert, Marc J. Gunter, Vivian Viallon
Summary: This study identified metabolites potentially associated with multiple cancer types and provided insights into shared pathways for cancer development.
Article
Gastroenterology & Hepatology
Edoardo Botteri, Giulia Peveri, Paula Berstad, Vincenzo Bagnardi, Sairah L. F. Chen, Torkjel M. Sandanger, Geir Hoff, Christina C. Dahm, Christian S. Antoniussen, Anne Tjonneland, Anne Kirstine Eriksen, Guri Skeie, Aurora Perez-Cornago, Jose Maria Huerta, Paula Jakszyn, Sophia Harlid, Bjoern Sundstroem, Aurelio Barricarte, Evelyn M. Monninkhof, Jeroen W. G. Derksen, Matthias B. Schulze, Bas Bueno-de-Mesquita, Maria-Jose Sanchez, Amanda J. Cross, Konstantinos K. Tsilidis, Maria Santucci De Magistris, Rudolf Kaaks, Verena Katzke, Joseph A. Rothwell, Nasser Laouali, Gianluca Severi, Pilar Amiano, Paolo Contiero, Carlotta Sacerdote, Marcel Goldberg, Mathilde Touvier, Heinz Freisling, Vivian Viallon, Elisabete Weiderpass, Elio Riboli, Marc J. Gunter, Mazda Jenab, Pietro Ferrari
Summary: This study investigated the impact of changes in lifestyle habits on the risk of colorectal cancer. The results showed that adhering to a healthy lifestyle was associated with a lower risk of colorectal cancer, while not adhering to a healthy lifestyle was associated with an increased risk of colorectal cancer.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Nutrition & Dietetics
Roland Wedekind, Joseph A. Rothwell, Vivian Viallon, Pekka Keski-Rahkonen, Julie A. Schmidt, Veronique Chajes, Vna Katzke, Theron Johnson, Maria Santucci de Magistris, Vittorio Krogh, Pilar Amiano, Carlotta Sacerdote, Daniel Redondo-Sanchez, Jose Maria Huerta, Anne Tjonneland, Pratik Pokharel, Paula Jakszyn, Rosario Tumino, Eva Ardanaz, Torkjel M. Sandanger, Anna Winkvist, Johan Hultdin, Matthias B. Schulze, Elisabete Weiderpass, Marc J. Gunter, Inge Huybrechts, Augustin Scalbert
Summary: Circulating levels of acylcarnitines (ACs) are influenced by various factors such as age, sex, diet, and fasting status. Different types of ACs are associated with corresponding fatty acids in plasma, specific food intake, and concentrations of branched-chain amino acids. Understanding the determinants of ACs can help interpret their associations with disease risk and provide insights into potential dietary and lifestyle factors for disease prevention.
CLINICAL NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Catalina Londono, Valerie Cayssials, Izar de Villasante, Marta Crous-Bou, Augustin Scalbert, Elisabete Weiderpass, Antonio Agudo, Anne Tjonneland, Anja Olsen, Kim Overvad, Verena Katzke, Matthias Schulze, Domenico Palli, Vittorio Krogh, Maria Santucci de Magistris, Rosario Tumino, Fulvio Ricceri, Inger T. Gram, Charlotta Rylander, Guri Skeie, Maria-Jose Sanchez, Pilar Amiano, Jose Maria Huerta, Aurelio Barricarte, Hanna Sartor, Emily Sonestedt, Anders Esberg, Annika Idahl, Yahya Mahamat-Saleh, Nasser Laouali, Marina Kvaskoff, Renee Turzanski-Fortner, Raul Zamora-Ros
Summary: The study found that total, classes, and subclasses of polyphenol intake were not significantly associated with epithelial ovarian cancer (EOC) risk in a large prospective study, except for a possible association with phenolic acid intake. Further investigation is needed to clarify the relationship between phenolic acid intake and EOC risk.
Article
Oncology
S. G. Yammine, I. Huybrechts, C. Biessy, L. Dossus, S. Panico, M. J. Sanchez, V. Benetou, R. Turzanski-Fortner, V. Katzke, A. Idahl, G. Skeie, K. Standahl Olsen, A. Tjonneland, J. Halkjaer, S. Colorado-Yohar, A. K. Heath, E. Sonestedt, H. Sartor, M. B. Schulze, D. Palli, M. Crous-Bou, A. Dorronsoro, K. Overvad, A. Barricarte Gurrea, G. Severi, R. C. H. Vermeulen, T. M. Sandanger, R. C. Travis, T. Key, P. Amiano, B. Van Guelpen, M. Johansson, M. Sund, R. Tumino, N. Wareham, C. Sacerdote, V. Krogh, P. Brennan, E. Riboli, E. Weiderpass, M. J. Gunter, V. Chajes
Summary: Specific dietary fatty acids, such as gamma-linolenic acid and alpha-linolenic acid from plant sources, may be associated with lower risk of endometrial cancer.
Review
Oncology
Alessandro Prete, Antonio Matrone, Carla Gambale, Liborio Torregrossa, Elisa Minaldi, Cristina Romei, Raffaele Ciampi, Eleonora Molinaro, Rossella Elisei
Summary: Researchers have produced promising data on the genetics and tumor microenvironment of poorly differentiated thyroid cancer and anaplastic thyroid cancer. Despite their rarity, these cancers pose a significant clinical problem due to poor survival and the inefficacy of traditional therapies. New evidence is changing the treatment landscape for these cancers.
Article
Nutrition & Dietetics
Leila Lujan-Barroso, Lucia Iglesias, Raul Zamora-Ros, Cristina Lasheras, Maria-Jose Sanchez, Natalia Cabrera-Castro, Josu Delfrad, Pilar Amiano, Esther Molina-Montes, Sandra Colorado-Yohar, Conchi Moreno-Iribas, Ane Dorronsoro, Miguel Rodriguez-Barranco, Maria Dolores Chirlaque, Amaia Aizpurua, Antonio Agudo, Jose Ramon Quiros, Paula Jakszyn
Summary: Recent evidence suggests that energy distribution during the daytime could be a potential determinant for the development of metabolic syndrome (MetS). This study aimed to assess the association between breakfast size and the prevalence of MetS in Spanish adults. The results showed that a larger breakfast size was associated with a lower prevalence of MetS.
Article
Nutrition & Dietetics
Heleen Van Puyvelde, Nikos Papadimitriou, Joanna Clasen, David Muller, Carine Biessy, Pietro Ferrari, Jytte Halkjaer, Kim Overvad, Anne Tjonneland, Renee T. Fortner, Verena Katzke, Matthias B. Schulze, Paolo Chiodini, Giovanna Masala, Valeria Pala, Carlotta Sacerdote, Rosario Tumino, Marije F. Bakker, Antonio Agudo, Eva Ardanaz, Maria Dolores Chirlaque Lopez, Maria-Jose Sanchez, Ulrika Ericson, Bjorn Gylling, Therese Karlsson, Jonas Manjer, Julie A. Schmidt, Genevieve Nicolas, Corinne Casagrande, Elisabete Weiderpass, Alicia K. Heath, Lode Godderis, Koen Van Herck, Dirk De Bacquer, Marc J. Gunter, Inge Huybrechts
Summary: The study did not find strong evidence for an association between methyl-group donors involved in one-carbon metabolism and breast cancer risk. However, there was a potential U-shaped trend suggested for dietary folate intake and breast cancer risk. Further research is needed to clarify this association.
Article
Oncology
Rosie K. Singleton, Alicia K. Heath, Joanna L. Clasen, Ghislaine Scelo, Mattias Johansson, Florence Le Calvez-Kelm, Elisabete Weiderpass, Fredrik Liedberg, Borje Ljungberg, Justin Harbs, Anja Olsen, Anne Tjonneland, Christina C. Dahm, Rudolf Kaaks, Renee T. Fortner, Salvatore Panico, Giovanna Tagliabue, Giovanna Masala, Rosario Tumino, Fulvio Ricceri, Inger T. Gram, Carmen Santiuste, Catalina Bonet, Miguel Rodriguez-Barranco, Mattias B. Schulze, Manuela M. Bergmann, Ruth C. Travis, Ioanna Tzoulaki, Elio Riboli, David C. Muller
Summary: The study found that the currently available RCC risk prediction models have limitations in identifying individuals at substantial risk of RCC in the general population. Further development, potentially incorporating biomarkers, is needed for more effective risk stratification of RCC.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Immunology
Feixue Wei, Ningshao Xia, Rebeca Ocampo, Marc T. Goodman, Nancy A. Hessol, Beatriz Grinsztejn, Ana P. Ortiz, Fanghui Zhao, Erna M. Kojic, Rupert Kaul, Isabelle Heard, Imran O. Morhason-Bello, Anna-Barbara Moscicki, Alexandra de Pokomandy, Joel M. Palefsky, Luana L. S. Rodrigues, Racheal S. Dube Mandishora, Reshmie A. Ramautarsing, Silvia Franceschi, Sheela Godbole, Fernanda K. Tso, Lynette J. Menezes, Chunqing Lin, Gary M. Clifford
Summary: Age-specific shifts in HPV16 prevalence from cervix to anus suggest that HPV infections may persist longer, or occur later in life, in the anus than cervix. This has important implications for using cervical screening results to direct anal cancer prevention.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Nutrition & Dietetics
Raul Zamora-Ros, Valerie Cayssials, Ramon Cleries, Maria Torrents, Graham Byrnes, Elisabete Weiderpass, Maria Sandstrom, Martin Almquist, Marie-Christine Boutron-Ruault, Anne Tjonneland, Cecilie Kyro, Verena A. Katzke, Charlotte Le Cornet, Giovanna Masala, Vittorio Krogh, Gabriella Iannuzzo, Rosario Tumino, Lorenzo Milani, Guri Skeie, Esther Ubago-Guisado, Pilar Amiano, Maria-Dolores Chirlaque, Eva Ardanaz, Suzanne Janzi, Linda Eriksson, Heinz Freisling, Alicia K. Heath, Sabina Rinaldi, Antonio Agudo
Summary: This study found that consumption of sweetened beverages was associated with an increased risk of differentiated thyroid cancer, while a dietary pattern characterized by alcohol consumption was associated with a decreased risk of thyroid cancer.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Oncology
Marko Lukic, Idlir Licaj, Maarit A. Laaksonen, Elisabete Weiderpass, Kristin B. Borch, Charlotta Rylander
Summary: This study assessed the burden of colon cancer in Norwegian women and identified modifiable risk factors associated with the disease. The findings indicate that a significant proportion of colon cancer cases among women in Norway can be attributed to modifiable risk factors, highlighting the potential of adopting a healthy lifestyle for prevention.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Nutrition & Dietetics
Anastasia Kanellou, Eleni Maria Papatesta, Georgia Martimianaki, Eleni Peppa, Maria Stratou, Antonia Trichopoulou
Summary: The use of dietary supplements is increasing worldwide, including in Greece where 31% of adults report using them. The most common supplements used are multivitamins with minerals, calcium, multivitamins, and iron. Women have a higher usage rate compared to men.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Oncology
Carlota Castro-Espin, Catalina Bonet, Marta Crous-Bou, Verena Katzke, Charlotte Le Cornet, Franziska Jannasch, Matthias B. Schulze, Anja Olsen, Anne Tjonneland, Christina C. Dahm, Christian S. Antoniussen, Maria Jose Sanchez, Pilar Amiano, Maria Dolores Chirlaque, Marcela Guevara, Claudia Agnoli, Rosario Tumino, Carlotta Sacerdote, Maria Santucci De Magistris, Malin Sund, Stina Boden, Torill Enget Jensen, Karina Standahl Olsen, Guri Skeie, Marc J. Gunter, Sabina Rinaldi, Esther M. Gonzalez-Gil, Elisabete Weiderpass, Sofia Christakoudi, Alicia K. Heath, Laure Dossus, Antonio Agudo
Summary: This study aimed to investigate the relationship between pre-diagnostic dietary patterns related to inflammatory, insulin, and estrogenic pathways and breast cancer (BC) survival. The results showed that adherence to an anti-diabetic and anti-inflammatory diet was associated with lower overall mortality among BC survivors, while no significant association was found with the estrogen-related dietary pattern. Therefore, following these dietary patterns could potentially improve the prognosis of BC survivors.
BRITISH JOURNAL OF CANCER
(2023)
Article
Nutrition & Dietetics
Conor James MacDonald, Anne-Laure Madkia, Claire Mounier-Vehier, Gianluca Severi, Marie-Christine Boutron-Ruault
Summary: This study finds that higher intake of saturated fat is associated with a higher risk of hypertension among women compared to other macronutrients such as monounsaturated or polyunsaturated fat.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Oncology
Manon Cairat, Anton Pottegard, Morten Olesen, Laure Dossus, Agnes Fournier, Blanaid Hicks
Summary: The use of antiplatelet drugs, including low-dose aspirin, clopidogrel, and dipyridamole, does not appear to be associated with a reduced risk of breast cancer. However, there may be a potential inverse association between dipyridamole use and breast cancer risk in women under 55 years old.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Ziling Mao, Jacqueline Roshelli Baker, Masayoshi Takeuchi, Hideyuki Hyogo, Anne Tjonneland, Anne Kirstine Eriksen, Gianluca Severi, Joseph Rothwell, Nasser Laouali, Verena Katzke, Rudolf Kaaks, Matthias B. Schulze, Domenico Palli, Sabina Sieri, Maria Santucci de Magistris, Rosario Tumino, Carlotta Sacerdote, Jeroen W. G. Derksen, Inger T. Gram, Guri Skeie, Torkjel M. Sandanger, Jose Ramon Quiros, Marta Crous-Bou, Maria-Jose Sanchez, Pilar Amiano, Sandra M. Colorado-Yohar, Marcela Guevara, Sophia Harlid, Ingegerd Johansson, Aurora Perez-Cornago, Heinz Freisling, Marc Gunter, Elisabete Weiderpass, Alicia K. Heath, Elom Aglago, Mazda Jenab, Veronika Fedirko
Summary: Glyceraldehyde-derived advanced glycation end products (glycer-AGEs) are associated with the development and progression of colorectal cancer due to their oxidative and inflammatory properties. This study found that circulating glycer-AGEs concentrations are positively associated with both colorectal cancer-specific and all-cause mortality. The association between glycer-AGEs and colorectal cancer-specific mortality is stronger in patients with distal colon cancer.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Elom K. Aglago, Amanda J. Cross, Elio Riboli, Veronika Fedirko, David J. Hughes, Agnes Fournier, Paula Jakszyn, Heinz Freisling, Marc J. Gunter, Christina C. Dahm, Kim Overvad, Anne Tjonneland, Cecilie Kyro, Marie-Christine Boutron-Ruault, Joseph A. Rothwell, Gianluca Severi, Verena Katzke, Bernard Srour, Matthias B. Schulze, Clemens Wittenbecher, Domenico Palli, Sabina Sieri, Fabrizio Pasanisi, Rosario Tumino, Fulvio Ricceri, Bas Bueno-de-Mesquita, Jeroen W. G. Derksen, Guri Skeie, Torill Enget Jensen, Marko Lukic, Maria-Jose Sanchez, Pilar Amiano, Sandra Colorado-Yohar, Aurelio Barricarte, Ulrika Ericson, Bethany van Guelpen, Keren Papier, Anika Knuppel, Corinne Casagrande, Inge Huybrechts, Alicia K. Heath, Konstantinos K. Tsilidis, Mazda Jenab
Summary: This study examined the association between dietary iron intake and colorectal cancer (CRC) risk. The results showed that in men, higher intake of non-heme iron was associated with a lower risk of CRC, while there was no significant association with total or heme iron intake. In women, there was no significant association between iron intake and CRC risk. Substituting heme iron with non-heme iron was associated with a lower risk of CRC in men.
BRITISH JOURNAL OF CANCER
(2023)
Article
Oncology
Xiaoshuang Feng, Wendy Yi-Ying Wu, Justina Ucheojor Onwuka, Zahra Haider, Karine Alcala, Karl Smith-Byrne, Hana Zahed, Florence Guida, Renwei Wang, Julie K. Bassett, Victoria Stevens, Ying Wang, Stephanie Weinstein, Neal D. Freedman, Chu Chen, Lesley Tinker, Therese Haugdahl Nost, Woon-Puay Koh, David Muller, Sandra M. Colorado-Yohar, Rosario Tumino, Rayjean J. Hung, Christopher Amos, Xihong Lin, Xuehong Zhang, Alan A. Arslan, Maria-Jose Sanchez, Elin Pettersen Sorgjerd, Gianluca Severi, Kristian Hveem, Paul Brennan, Arnulf Langhammer, Roger L. Milne, Jian-Min Yuan, Beatrice Melin, Mikael Johansson, Hilary A. Robbins, Mattias Johansson
Summary: This study aimed to develop a proteomics-based risk model for lung cancer and compare its performance with a smoking-based risk model and a commercially available autoantibody biomarker test. We conducted a case-control study in 6 prospective cohorts, involving 624 lung cancer participants and 624 smoking-matched cancer free participants. The protein-based risk model showed promise in predicting incident lung cancer and outperformed the standard risk prediction model and the commercialized EarlyCDT-Lung.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Clinical Neurology
Thi Thu Ha Nguyen, Agnes Fournier, Emeline Courtois, Fanny Artaud, Sylvie Escolano, Pascale Tubert-Bitter, Marie-Christine Boutron-Ruault, Isabelle Degaey, Emmanuel Roze, Marianne Canonico, Ismail Ahmed, Anne C. M. Thiebaut, Alexis Elbaz
Summary: This study examined the association between statin use and Parkinson's disease (PD) incidence using data from a cohort study of French women. The results showed that the use of lipophilic statins at least 5 years earlier was associated with a reduced incidence of PD in women, with a dose-response relationship for the mean daily dose.
MOVEMENT DISORDERS
(2023)
Article
Endocrinology & Metabolism
Sofia Christakoudi, Konstantinos K. Tsilidis, Evangelos Evangelou, Elio Riboli
Summary: Obesity is associated with low-grade inflammation and increased risk of venous thromboembolism, but the associations with platelet count and body shape are unclear. This study used different body shape indices to evaluate the associations of body mass index (BMI), allometric body shape index (ABSI), and hip index (HI) with platelet count and size. The results showed that the associations vary between different groups and factors such as sex, age, alcohol consumption, and smoking play a role.
BIOLOGY OF SEX DIFFERENCES
(2023)
Article
Hematology
Monique J. T. Crobach, Rayna J. S. Anijs, Sigrid K. Braekkan, Marianne T. Severinsen, Jens Hammerstrom, Hanne Skille, Soren R. Kristensen, Benedikte Paulsen, Anne Tjonneland, Henri H. Versteeg, Kim Overvad, John-Bjarne Hansen, Inger A. Naess, Suzanne C. Cannegieter
Summary: Patients with cancer have a higher risk of developing venous thromboembolism (VTE), which leads to poorer survival compared to cancer alone. This study aimed to investigate the impact of VTE on cancer patients' survival in a general population. The findings showed that cancer patients with VTE had a 3.4-fold higher risk of death compared to those without VTE, regardless of cancer type.
Article
Nutrition & Dietetics
Inge Huybrechts, Inarie Jacobs, Elom K. Aglago, Sahar Yammine, Michele Matta, Julie A. Schmidt, Corinne Casagrande, Genevieve Nicolas, Carine Biessy, Heleen Van Puyvelde, Augustin Scalbert, Jeroen W. G. Derksen, Yvonne T. van der Schouw, Sara Grioni, Pilar Amiano, Jytte Halkjaer, Anne Tjonneland, Jose M. Huerta, Leila Lujan-Barroso, Domenico Palli, Marc J. Gunter, Aurora Perez-Cornago, Veronique Chajes
Summary: This study aims to investigate the relationship between dietary fatty acid (FA) intake and plasma phospholipid (PL) FA levels in the EPIC cohort. Dietary intake of 60 individual FAs was estimated using validated questionnaires, and plasma PL FA concentrations were measured in non-fasting venous plasma samples. The results showed moderate positive correlations between FA intakes and plasma PL FA levels for certain FAs, especially for health-enhancing long-chain polyunsaturated FAs and health-deteriorating trans-FA.
