Review
Nutrition & Dietetics
Raymond Pranata, Andrea Feraldho, Michael Anthonius Lim, Joshua Henrina, Rachel Vania, Nyoman Golden, Julius July
Summary: This systematic review and meta-analysis examined the association between coffee and tea consumption and the risk of glioma. The findings suggest that higher coffee consumption may be associated with a lower risk of glioma, and higher tea consumption is linked to a decreased risk of glioma.
BRITISH JOURNAL OF NUTRITION
(2022)
Review
Nutrition & Dietetics
Hui Luo, Hong Ge
Summary: This meta-analysis suggests that drinking hot tea is significantly associated with an increased risk of esophageal squamous cell carcinoma (ESCC), but not with esophageal adenocarcinoma (EAC).
FRONTIERS IN NUTRITION
(2022)
Review
Oncology
Weichunbai Zhang, Jing Jiang, Yongqi He, Xinyi Li, Shuo Yin, Feng Chen, Wenbin Li
Summary: This meta-analysis study found that nitrite increases the risk of glioma in adults, while nitrate increases the risk of brain tumors in children. Therefore, the effects of nitrite and nitrate on glioma should not be ignored.
FRONTIERS IN ONCOLOGY
(2022)
Review
Nutrition & Dietetics
Kimia Torabynasab, Hossein Shahinfar, Nastaran Payandeh, Shima Jazayeri
Summary: This study aimed to examine the correlation between dietary caffeine (coffee and tea) intake and the presence of depressive symptoms in adults. The findings suggest that coffee and dietary caffeine may have a protective effect against the development of depression, while no evidence suggesting a link between tea consumption and reduced depressive symptoms has been found.
FRONTIERS IN NUTRITION
(2023)
Article
Multidisciplinary Sciences
Irma Karabegovic, Eliana Portilla-Fernandez, Yang Li, Jiantao Ma, Silvana C. E. Maas, Daokun Sun, Emily A. Hu, Brigitte Kuhnel, Yan Zhang, Srikant Ambatipudi, Giovanni Fiorito, Jian Huang, Juan E. Castillo-Fernandez, Kerri L. Wiggins, Niek de Klein, Sara Grioni, Brenton R. Swenson, Silvia Polidoro, Jorien L. Treur, Cyrille Cuenin, Pei-Chien Tsai, Ricardo Costeira, Veronique Chajes, Kim Braun, Niek Verweij, Anja Kretschmer, Lude Franke, Joyce B. J. van Meurs, Andre G. Uitterlinden, Robert J. de Knegt, M. Arfan Ikram, Abbas Dehghan, Annette Peters, Ben Schottker, Sina A. Gharib, Nona Sotoodehnia, Jordana T. Bell, Paul Elliott, Paolo Vineis, Caroline Relton, Zdenko Herceg, Hermann Brenner, Melanie Waldenberger, Casey M. Rebholz, Trudy Voortman, Qiuwei Pan, Myriam Fornage, Daniel Levy, Manfred Kayser, Mohsen Ghanbari
Summary: This study found that coffee intake is associated with differential DNA methylation levels at multiple CpGs in a large cohort of European and African-American participants from 15 cohorts.
NATURE COMMUNICATIONS
(2021)
Article
Oncology
Yun Zhu, Yirong Teng, Shuangyan Xu, Yinde Xu, Boheng Zhu, Weimin Yan, Jie Liu
Summary: Eczema may be inversely associated with the risk of brain cancer, glioma, meningioma, and acoustic neuroma, especially in individuals over the age of 16. Additionally, eczema significantly decreases the risk of glioma in Europeans.
Review
Oncology
Jinchuan Yu, Di Liang, Jiujiu Li, Zhengxiang Liu, Fuding Zhou, Ting Wang, Shaodi Ma, Guangjun Wang, Baochun Chen, Wenjun Chen
Summary: Multiple studies suggest that higher intake of coffee or green tea may be associated with a lower risk of hepatocellular carcinoma (HCC). A meta-analysis of observational studies, involving a total of 32 studies and over 4 million participants, confirmed this association. Drinking coffee or green tea may be a potentially effective approach for the prevention or mitigation of HCC, but further well-designed observational studies and clinical experimental research are needed for confirmation.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2023)
Article
Pharmacology & Pharmacy
Jie Wang, Jing Gao, Hong-li Xu, Ying Qian, Li Xie, Herbert Yu, Bi-yun Qian
Summary: This study found a negative association between Citrus fruit intake and lung cancer risk. Moreover, there was a nonlinear dose-response relationship between Citrus intake and lung cancer risk within a certain range.
PHARMACOLOGICAL RESEARCH
(2021)
Review
Geriatrics & Gerontology
Mengyuan Shi, Limin Cao, Huiyuan Liu, Yuhan Zhou, Yuhong Zhao, Yang Xia
Summary: A meta-analysis was conducted to investigate the association between tea drinking and cognitive disorders in older adults. The results showed that tea drinking was negatively associated with cognitive disorders, and a dose-response relationship was found.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Nutrition & Dietetics
Farzaneh Asoudeh, Fatemeh Dashti, Ahmad Jayedi, Amirhossein Hemmati, Abdulmannan Fadel, Hamed Mohammadi
Summary: This meta-analysis examined the association between dietary caffeine, different types of coffee and tea consumption, and the risk of rheumatoid arthritis (RA). The results showed that higher intake of coffee and decaffeinated coffee was associated with an increased risk of RA, while there was no significant association between caffeinated coffee, tea, or caffeine intake and RA risk.
FRONTIERS IN NUTRITION
(2022)
Review
Nutrition & Dietetics
Jiaying Ni, Ping Wang, Tao Zheng, Long Lv, Hao Peng
Summary: The study suggests that there is no significant association between coffee intake and the risk of gestational diabetes mellitus, but in studies conducted in non-Asia countries, coffee consumption may have an inverse relationship with GDM risk. Further large-scale cohort studies are needed to confirm these findings.
FRONTIERS IN NUTRITION
(2021)
Review
Nutrition & Dietetics
Long Shu, Dan Yu, Fubi Jin
Summary: This systematic review and meta-analysis found that healthy dietary patterns, as well as high intakes of vegetables and fruits, were significantly associated with a lower risk of glioma. However, there was no significant association between intakes of fresh fish, nuts, whole grains, dairy products, and glioma risk.
FRONTIERS IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Weichunbai Zhang, Jing Jiang, Xinyi Li, Yongqi He, Feng Chen, Wenbin Li
Summary: This study quantitatively evaluated the association between dietary intakes and glioma using a meta-analysis. The results indicated that increased intakes of tea, total vegetables, green vegetables, and orange vegetables may reduce the risk of glioma, while increased intakes of grains, processed meats, and processed fish may increase the risk of glioma. The findings highlight the importance of dietary factors in glioma prevention.
FRONTIERS IN NUTRITION
(2022)
Review
Food Science & Technology
Farzaneh Asoudeh, Amir Bagheri, Bagher Larijani, Ahmad Esmaillzadeh
Summary: The association between coffee consumption and risk of fracture is inconclusive, while caffeine intake is positively associated with risk, according to this updated systematic review and meta-analysis.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Public, Environmental & Occupational Health
Zining Luo, Zhenglong Liu, Hongjie Chen, Ying Liu, Nenghuan Tang, Haoran Li
Summary: This meta-analysis evaluates the impact of light at night (LAN) exposure on breast cancer risk. The results show that exposure to LAN is associated with an increased risk of breast cancer, particularly in the Asian population.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Oncology
Luca Giraldi, Jovana Stojanovic, Dario Arzani, Roberto Persiani, Jinfu Hu, Kenneth C. Johnson, Zuo-Feng Zhang, Monica Ferraroni, Domenico Palli, Guo-Pei Yu, Carlo La Vecchia, Claudio Pelucchi, Nuno Lunet, Ana Ferro, Reza Malekzadeh, Joshua Muscat, David Zaridze, Dmitry Maximovich, Nuria Aragones, Vicente Martin, Jesus Vioque, Eva M. Navarrete-Munoz, Mohammadreza Pakseresht, Eva Negri, Matteo Rota, Farhad Pourfarzi, Lina Mu, Robert C. Kurtz, Areti Lagiou, Pagona Lagiou, Roberta Pastorino, Stefania Boccia
Summary: This study aimed to examine the association between height and risk of gastric cancer. Through a large pooled analysis of case-control studies, the study found no significant association between adult height and gastric cancer.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2023)
Article
Nutrition & Dietetics
Federica Turati, Marta Rossi, Panagiota Strikoudi, Monica Ferraroni, Maria Parpinel, Diego Serraino, Eva Negri, Carlo La Vecchia
Summary: This study found a positive association between dietary intake of branched-chain amino acids (BCAA) and pancreatic cancer risk. The association persisted even after excluding subjects with diabetes and family history of pancreatic cancer. These findings support previous research on the link between circulating BCAA and pancreatic cancer.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Dentistry, Oral Surgery & Medicine
Neerav Goyal, Max Hennessy, Erik Lehman, Wenxue Lin, Antonio Agudo, Wolfgang Ahrens, Stefania Boccia, Paul Brennan, Hermann Brenner, Gabriella Cadoni, Cristina Canova, Chu Chen, David Conway, Maria Paula Curado, Luigino Dal Maso, Alexander W. Daudt, Valeria Edefonti, Eleonora Fabianova, Leticia Fernandez, Silvia Franceschi, Werner Garavello, Maura Gillison, Richard B. Hayes, Claire Healy, Rolando Herrero, Ivana Holcatova, Jossy L. Kanda, Karl Kelsey, Bo T. Hansen, Rosalina Koifman, Pagona Lagiou, Carlo La Vecchia, Fabio Levi, Guojun Li, Jolanta Lissowska, Rossana Mendoza Lopez, Daniele Luce, Gary Macfarlane, Dana Mates, Keitaro Matsuo, Michael McClean, Ana Menezes, Gwenn Menvielle, Hal Morgenstern, Kirsten Moysich, Eva Negri, Andrew F. Olshan, Tamas Pandics, Jerry Polesel, Mark Purdue, Loredana Radoi, Heribert Ramroth, Lorenzo Richiardi, Stimson Schantz, Stephen M. Schwartz, Diego Serraino, Oxana Shangina, Elaine Smith, Erich M. Sturgis, Beata Swiatkowska, Peter Thomson, Thomas L. Vaughan, Marta Vilensky, Deborah M. Winn, Victor Wunsch-Filho, Guo-Pei Yu, Jose P. Zevallos, Zuo-Feng Zhang, Tongzhang Zheng, Ariana Znaor, Paolo Boffetta, Mia Hashibe, Yuan-Chin A. Lee, Joshua E. Muscat
Summary: This study analyzed the relationship between cigarette smoking, alcohol consumption, and head and neck cancer risk factors in less developed and more developed countries. The results showed that the duration of smoking and alcohol consumption had different effects on the risk of specific cancer sites depending on the country's level of development. These findings suggest that the degree of industrialization and economic development affects the relationship between smoking, alcohol, and head and neck cancer.
Review
Public, Environmental & Occupational Health
Periklis Charalampous, Juanita A. Haagsma, Lea S. Jakobsen, Vanessa Gorasso, Isabel Noguer, Alicia Padron-Monedero, Rodrigo Sarmiento, Joao Vasco Santos, Scott A. McDonald, Dietrich Plass, Grant M. A. Wyper, Ricardo Assuncao, Elena von der Lippe, Balazs Adam, Ala'a AlKerwi, Jalal Arabloo, Ana Lucia Baltazar, Boris Bikbov, Maria Borrell-Pages, Iris Brus, Genc Burazeri, Serafeim C. Chaintoutis, Jose Chen-Xu, Nino Chkhaberidze, Seila Cilovic-Lagarija, Barbara Corso, Sarah Cuschieri, Carlotta Di Bari, Keren Dopelt, Mary Economou, Theophilus Emeto, Peter Fantke, Florian Fischer, Alberto Freitas, Juan Manuel Garcia-Gonzalez, Federica Gazzelloni, Mika Gissler, Artemis Gkitakou, Hakan Gulmez, Sezgin Gunes, Sebastian Haller, Romana Haneef, Cesar A. Hincapie, Paul Hynds, Jane Idavain, Milena Ilic, Irena Ilic, Gaetano Isola, Zubair Kabir, Maria Kamusheva, Pavel Kolkhir, Naime Meric Konar, Polychronis Kostoulas, Mukhtar Kulimbet, Carlo La Vecchia, Paolo Lauriola, Miriam Levi, Marjeta Majer, Enkeleint A. Mechili, Lorenzo Monasta, Stefania Mondello, Javier Munoz Laguna, Evangelia Nena, Edmond S. W. Ng, Paul Nguewa, Vikram Niranjan, Iskra Alexandra Nola, Ronan O'Caoimh, Marija Obradovic, Elena Pallari, Mariana Peyroteo, Vera Pinheiro, Nurka Pranjic, Miguel Reina Ortiz, Silvia Riva, Cornelia Melinda Adi Santoso, Milena Santric Milicevic, Tugce Schmitt, Niko Speybroeck, Maximilian Sprugel, Paschalis Steiropoulos, Aleksandar Stevanovic, Lau Caspar Thygesen, Fimka Tozija, Brigid Unim, Hilal Bektas Uysal, Orsolya Varga, Milena Vasic, Rafael Jose Vieira, Vahit Yigit, Brecht Devleesschauwer, Sara M. Pires
Summary: This systematic literature review provides an overview of studies applying the disability-adjusted life years (DALY) concept for infectious diseases in European countries. Among the 105 included studies, food- and water-borne diseases were the most frequently studied. The number of burden of infectious disease studies has increased over time, but there is less consensus in methodological approaches.
EPIDEMIOLOGY AND INFECTION
(2023)
Article
Oncology
Giulia Collatuzzo, Carlo La Vecchia, Fabio Parazzini, Gianfranco Alicandro, Federica Turati, Matteo Di Maso, Matteo Malvezzi, Claudio Pelucchi, Eva Negri, Paolo Boffetta
Summary: This study provides a comprehensive assessment of infection-related cancers burden in Italy. It shows that 7.6% of cancer deaths and 6.9% of incident cases are attributable to infections, with higher proportions in men than women. Helicobacter pylori is the leading cause of infection-related cancer deaths, followed by hepatitis C virus, human immunodeficiency virus, and hepatitis B virus.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Oncology
Margherita Pizzato, Giulia Collatuzzo, Claudia Santucci, Matteo Malvezzi, Paolo Boffetta, Alessandro Comandone, Fabio Levi, Carlo La Vecchia, Paola Bertuccio, Eva Negri
Summary: This study provides mortality trends for soft-tissue sarcomas (STSs) in selected countries worldwide over the last 2 decades, along with predicted figures for 2025. The results show an increase in the number of deaths and mortality rates in most countries for both sexes. In 2025, the number of STS deaths is predicted to continue increasing in most countries and both sexes.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2023)
Article
Nutrition & Dietetics
Federica Turati, Federica Concina, Paola Bertuccio, Federica Fiori, Maria Parpinel, Martina Taborelli, Valentina Rosato, Werner Garavello, Eva Negri, Carlo La Vecchia
Summary: This study aimed to evaluate the association between the intake of specific fibers with prebiotic activity and laryngeal cancer risk. The results showed that the intake of kestose, raffinose, and stachyose was inversely associated with laryngeal cancer risk, while ITFs, nystose, and 1F-beta-fructofuranosylnystose were not associated with the risk. Current smokers and heavy drinkers with low intake of prebiotic fibers had a significantly higher risk of laryngeal cancer compared to never smokers and moderate drinkers with high intake of prebiotic fibers.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Review
Oncology
Antonio Cioffi, Ottavio De Cobelli, Paolo Veronesi, Carlo La Vecchia, Patrick Maisonneuve, Giovanni Corso
Summary: This systematic review and meta-analysis found that germline BRCA1 variants are more prevalent in Ashkenazi Jewish men with prostate cancer, while BRCA2 variants show a similar distribution between Ashkenazi and non-Ashkenazi populations. This suggests that genetic screening for prostate cancer in Ashkenazi men should not be limited to the BRCA2 gene.
Review
Biochemistry & Molecular Biology
Simona Servida, Elena Panzeri, Laura Tomaino, Giovanni Marfia, Emanuele Garzia, Giuseppe Ciniglio Appiani, Gianluca Moroncini, Vito De Gennaro Colonna, Carlo La Vecchia, Luisella Vigna
Summary: This article discusses a case study of a helicopter pilot who experienced transient loss of consciousness during a low-altitude flight under curcumin and piperine treatment. Further investigation revealed the presence of previously asymptomatic insulinoma. The researchers hypothesize that the combined effects of curcumin and piperine may have caused severe hypoglycemia and subsequent loss of consciousness. Thus, more studies are needed to evaluate the safety of curcumin and piperine supplementation in individuals with impaired glucose metabolism and insulin secretion.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, Legal
Sofia Pavanello, Angelo Moretto, Carlo La Vecchia, Gianfranco Alicandro
Summary: Many studies have been conducted on the relationship between non-sugar sweeteners (NSS) and cancer in the past five decades, but the issue still remains of interest. In this comprehensive review, both toxicological and epidemiological evidence on the possible link between NSS consumption and cancer risk were quantitatively evaluated. The majority of studies showed no associations between NSS consumption and cancer, and the risks found in a few studies were not confirmed by others. Based on the review of both experimental and epidemiological data, it can be concluded that there is no evidence of cancer risk associated with NSS consumption.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Oncology
Michele Sassano, Marco Mariani, Claudio Pelucchi, Nuno Lunet, Samantha Morais, Vicente Martin, Victor Moreno, Maria Paula Curado, Emmanuel Dias-Neto, Marcis Leja, Evita Gasenko, Carlo La Vecchia, Stefania Boccia, Roberta Pastorino
Summary: This study found a potential association between proton-pump inhibitors (PPI) and gastric cancer, which may be mainly due to reverse causality. The results showed that short-term use of PPIs may increase the risk of gastric cancer, but this association becomes non-significant after using PPIs for more than 3 years.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Nutrition & Dietetics
Marta Rossi, Malak Khalifeh, Federica Fiori, Maria Parpinel, Diego Serraino, Claudio Pelucchi, Eva Negri, Attilio Giacosa, Anna Crispo, Giulia Collatuzzo, Yusuf Hannun, Chiara Luberto, Carlo La Vecchia, Paolo Boffetta
Summary: This study found an inverse association between choline intake and colorectal cancer (CRC) risk, but inconsistent findings were observed. On the other hand, sphingomyelin (SM) choline moiety was not associated with CRC risk. These results suggest that choline intake may be a favorable factor for preventing CRC.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Medical Laboratory Technology
Ali Esmaeili-Nadimi, Fatemeh Imanparast, Samira Alizadeh, Akram Vatannejad, Pegah Mohaghegh, Seyed M. Seyedmehdi, Carlo La Vecchia, Zahra Jamali
Summary: This study investigated the relationship between total antioxidant capacity (TAC), total oxidant status (TOS), TAC/TOS levels, and disease severity in hospitalized patients with COVID-19. The results showed no significant difference in serum levels of TAC, TOS, and TAC/TOS in terms of disease severity.
CLINICAL LABORATORY
(2023)
Article
Oncology
Mark Lawler, Lynne Davis, Simon Oberst, Kathy Oliver, Alexander Eggermont, Anna Schmutz, Carlo La Vecchia, Claudia Allemani, Yolande Lievens, Peter Naredi, Tanja Cufer, Ajay Aggarwal, Matti Aapro, Kathi Apostolidis, Anne-Marie Baird, Fatima Cardoso, Andreas Charalambous, Michel P. Coleman, Alberto Costa, Mirjam Crul, Csaba L. Degi, Federica Di Nicolantonio, Sema Erdem, Marius Geanta, Jan Geissler, Jacek Jassem, Beata Jagielska, Bengt Jonsson, Daniel Kelly, Olaf Kelm, Teodora Kolarova, Tezer Kutluk, Grant Lewison, Francoise Meunier, Jana Pelouchova, Thierry Philip, Richard Price, Beate Rau, Isabel T. Rubio, Peter Selby, Maja Juznic Sotlar, Gilliosa Spurrier-Bernard, Jolanda C. van Hoeve, Eduard Vrdoljak, Willien Westerhuis, Urszula Wojciechowska, Richard Sullivan
Summary: Cancer research is vital for improving cancer care, and patients treated in research-active hospitals have better outcomes. However, the COVID-19 pandemic has negatively impacted cancer outcomes in Europe and set back progress by almost a decade. The Lancet Oncology European Groundshot Commission aims to use detailed data on cancer research to inform future cancer care strategies in Europe.
Article
Health Care Sciences & Services
Andrea Piccinini, Paolo Bailo, Giussy Barbara, Monica Miozzo, Silvia Tabano, Patrizia Colapietro, Claudia Fare, Silvia Maria Sirchia, Elena Battaglioli, Paola Bertuccio, Giulia Manenti, Laila Micci, Carlo La Vecchia, Alessandra Kustermann, Simona Gaudi
Summary: Violence against women has negative consequences on their health. The EpiWE project aims to investigate the epigenetic signatures associated with intimate partner and sexual violence-induced stress-related disorders. The study found abnormal methylation levels of brain-derived neurotrophic factor, dopamine receptor D2, and insulin-like growth factor 2 genes in victims, indicating potential molecular pathways for addressing the long-term effects of violence and implementing precision medicine protocols.
