Improving Radioresponse Through Modification of the Tumor Immunological Microenvironment

Influence of bone marrow-derived hematopoietic cells on the tumor response to radiotherapy: Experimental models and clinical perspectives

(2011) G-One Ahn et al.   CELL CYCLE

Metronomic scheduling of anticancer treatment: the next generation of multitarget therapy?

(2011) Nicolas André et al.   Future Oncology

Immunomodulatory effects of anti-angiogenic drugs

(2011) A Heine et al.   LEUKEMIA

Upfront gefitinib/erlotinib treatment followed by concomitant radiotherapy for advanced lung cancer: A mono-institutional experience

(2011) Chih-Chia Chang et al.   LUNG CANCER

Immune parameters affecting the efficacy of chemotherapeutic regimens

(2011) Laurence Zitvogel et al.   Nature Reviews Clinical Oncology

Colony stimulating factor-1 receptor as a target for small molecule inhibitors

(2010) Baratali Mashkani et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Neoadjuvant Immunotherapy Enhances Radiosensitivity Through Natural Killer Cell Activation

(2010) Chau-Hwa Chi et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation

(2010) Kavya Rakhra et al.   CANCER CELL

PDGFR Signaling Blockade in Marrow Stroma Impairs Lung Cancer Bone Metastasis

(2010) R. Catena et al.   CANCER RESEARCH

Direct and Differential Suppression of Myeloid-Derived Suppressor Cell Subsets by Sunitinib Is Compartmentally Constrained

(2010) Jennifer S. Ko et al.   CANCER RESEARCH

Depletion of Tumor-Associated Macrophages Enhances the Effect of Sorafenib in Metastatic Liver Cancer Models by Antimetastatic and Antiangiogenic Effects

(2010) W. Zhang et al.   CLINICAL CANCER RESEARCH

Differential Gene Expression Profiles of Radioresistant Non–Small-Cell Lung Cancer Cell Lines Established by Fractionated Irradiation: Tumor Protein p53-Inducible Protein 3 Confers Sensitivity to Ionizing Radiation

(2010) Young Sook Lee et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Angiogenic Blockade and Radiotherapy in Hepatocellular Carcinoma

(2010) Kwan-Hwa Chi et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Immune Regulation of Cancer

(2010) Mary L. Disis   JOURNAL OF CLINICAL ONCOLOGY

Future directions of bone-targeted therapy for metastatic breast cancer

(2010) Tomifumi Onishi et al.   Nature Reviews Clinical Oncology

Combination of sunitinib, cetuximab and irradiation in an orthotopic head and neck cancer model

(2009) A. Bozec et al.   ANNALS OF ONCOLOGY

Silencing or Fueling Metastasis with VEGF Inhibitors: Antiangiogenesis Revisited

(2009) Sonja Loges et al.   CANCER CELL

Role of polymorphic Fc gamma receptor IIIa and EGFR expression level in cetuximab mediated, NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells

(2009) Andrés López-Albaitero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies

(2009) J. Ozao-Choy et al.   CANCER RESEARCH

A “Vascular Normalization Index” as Potential Mechanistic Biomarker to Predict Survival after a Single Dose of Cediranib in Recurrent Glioblastoma Patients

(2009) A. Gregory Sorensen et al.   CANCER RESEARCH

Phase I/II Trial of Bevacizumab and Radiotherapy for Locally Advanced Inoperable Colorectal Cancer: Vasculature-Independent Radiosensitizing Effect of Bevacizumab

(2009) M. I. Koukourakis et al.   CLINICAL CANCER RESEARCH

Increasing Sensitivity to Radiotherapy and Chemotherapy by Using Novel Biological Agents that Alter the Tumor Microenvironment

(2009) E. Shinohara et al.   CURRENT MOLECULAR MEDICINE

Overcoming the Hurdles of Tumor Immunity by Targeting Regulatory Pathways in Innate and Adaptive Immune Cells

(2009) Norberto Zwirner et al.   CURRENT PHARMACEUTICAL DESIGN

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

Epidermal Growth Factor Receptor Inhibition Modulates the Microenvironment by Vascular Normalization to Improve Chemotherapy and Radiotherapy Efficacy

(2009) George J. Cerniglia et al.   PLoS One

Combined effects of bevacizumab with erlotinib and irradiation: a preclinical study on a head and neck cancer orthotopic model

(2008) A Bozec et al.   BRITISH JOURNAL OF CANCER

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

(2008) C. Marcela Diaz-Montero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Molecular Interactions between Dying Tumor Cells and the Innate Immune System Determine the Efficacy of Conventional Anticancer Therapies

(2008) L. Apetoh et al.   CANCER RESEARCH

TS-1 enhances the effect of radiotherapy by suppressing radiation-induced hypoxia-inducible factor-1 activation and inducing endothelial cell apoptosis

(2008) Lihua Zeng et al.   CANCER SCIENCE

T-Cell Responses to Survivin in Cancer Patients Undergoing Radiation Therapy

(2008) D. Schaue et al.   CLINICAL CANCER RESEARCH

Combination of Vascular Endothelial Growth Factor Receptor/Platelet-Derived Growth Factor Receptor Inhibition Markedly Improves Radiation Tumor Therapy

(2008) C. Timke et al.   CLINICAL CANCER RESEARCH

Enhancement of Antitumor Radiation Efficacy and Consistent Induction of the Abscopal Effect in Mice by ECI301, an Active Variant of Macrophage Inflammatory Protein-1 

(2008) K. Shiraishi et al.   CLINICAL CANCER RESEARCH

The anticancer immune response: indispensable for therapeutic success?

(2008) Laurence Zitvogel et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of Recombinant Adenovirus-p53 Combined With Radiotherapy on Long-Term Prognosis of Advanced Nasopharyngeal Carcinoma

(2008) Jian-ji Pan et al.   JOURNAL OF CLINICAL ONCOLOGY

Mechanisms Involved in Radiation Enhancement of Intratumoral Dendritic Cell Therapy

(2008) Seagal Teitz-Tennenbaum et al.   JOURNAL OF IMMUNOTHERAPY

The essential role of the in situ immune reaction in human colorectal cancer

(2008) Franck Pagès et al.   JOURNAL OF LEUKOCYTE BIOLOGY