miRNA biogenesis: Biological impact in the development of cancer

Polymorphisms in MicroRNA-Related Genes Are Associated With Survival of Patients With T-Cell Lymphoma

(2014) X. Li et al.   ONCOLOGIST

Estrogen Regulates the Tumour Suppressor MiRNA-30c and Its Target Gene, MTA-1, in Endometrial Cancer

(2014) Xiangyi Kong et al.   PLoS One

DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification

(2013) C. Vanesa Díaz-García et al.   CARCINOGENESIS

Nuclear Death Receptor TRAIL-R2 Inhibits Maturation of Let-7 and Promotes Proliferation of Pancreatic and Other Tumor Cells

(2013) Verena Haselmann et al.   GASTROENTEROLOGY

Mutant p53 Regulates Dicer through p63-dependent and -independent Mechanisms to Promote an Invasive Phenotype

(2013) Patricia A. J. Muller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

(2013) Yael Nemlich et al.   JOURNAL OF CLINICAL INVESTIGATION

A low dicer expression is associated with resistance to 5-FU-based chemoradiotherapy and a shorter overall survival in patients with oral squamous cell carcinoma

(2013) Kenta Kawahara et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma

(2013) Seyed Mehdi Jafarnejad et al.   MODERN PATHOLOGY

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

(2013) Jia Shen et al.   NATURE

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Loop-miRs: active microRNAs generated from single-stranded loop regions

(2013) Julia Winter et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs Distinguish Cytogenetic Subgroups in Pediatric AML and Contribute to Complex Regulatory Networks in AML-Relevant Pathways

(2013) Svenja Daschkey et al.   PLoS One

Dynamic Localisation of Mature MicroRNAs in Human Nucleoli is Influenced by Exogenous Genetic Materials

(2013) Zhou Fang Li et al.   PLoS One

Prognostic Significance of Deregulated Dicer Expression in Breast Cancer

(2013) Emer Caffrey et al.   PLoS One

RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators

(2013) A. D. Redfern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Argonaute-3 activates the let-7a passenger strand microRNA

(2013) Julia Winter et al.   RNA Biology

Deep Sequencing and High-Resolution Imaging Reveal Compartment-Specific Localization of Bdnf mRNA in Hippocampal Neurons

(2013) T. J. Will et al.   Science Signaling

Disruption of CTCF at the miR-125b1 locus in gynecological cancers

(2012) Ernesto Soto-Reyes et al.   BMC CANCER

Rolling the Dice to Discover the Role of DICER in Tumorigenesis

(2012) Veronica Davalos et al.   CANCER CELL

miR-23b Represses Proto-oncogene Src Kinase and Functions as Methylation-Silenced Tumor Suppressor with Diagnostic and Prognostic Significance in Prostate Cancer

(2012) S. Majid et al.   CANCER RESEARCH

Downregulated Dicer expression predicts poor prognosis in chronic lymphocytic leukemia

(2012) Dan-Xia Zhu et al.   CANCER SCIENCE

Human RNA Methyltransferase BCDIN3D Regulates MicroRNA Processing

(2012) Blerta Xhemalce et al.   CELL

Mono-Uridylation of Pre-MicroRNA as a Key Step in the Biogenesis of Group II let-7 MicroRNAs

(2012) Inha Heo et al.   CELL

Effect of miR-451 on the Biological Behavior of the Esophageal Carcinoma Cell Line EC9706

(2012) Tao Wang et al.   DIGESTIVE DISEASES AND SCIENCES

Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients

(2012) Bruno Vincenzi et al.   EUROPEAN JOURNAL OF CANCER

Epigenetics of Colorectal Cancer

(2012) Ajay Goel et al.   GASTROENTEROLOGY

Androgen-regulated processing of the oncomir MiR-27a, which targets Prohibitin in prostate cancer

(2012) Claire E. Fletcher et al.   HUMAN MOLECULAR GENETICS

BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex

(2012) Shinji Kawai et al.   JOURNAL OF CELL BIOLOGY

Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells

(2012) Yukti Choudhury et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of Dicer and Drosha in triple-negative breast cancer

(2012) Nadia Passon et al.   JOURNAL OF CLINICAL PATHOLOGY

The Multiple Functions of TRBP, at the Hub of Cell Responses to Viruses, Stress, and Cancer

(2012) S. M. Daniels et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Argonaute identity defines the length of mature mammalian microRNAs

(2012) Prasanna Kumar Juvvuna et al.   NUCLEIC ACIDS RESEARCH

microRNAs associated with the different human Argonaute proteins

(2012) A. Dueck et al.   NUCLEIC ACIDS RESEARCH

Direct regulation of microRNA biogenesis and expression by estrogen receptor beta in hormone-responsive breast cancer

(2012) O Paris et al.   ONCOGENE

Immunohistochemical study of Dicer and Drosha expression in the benign and malignant lesions of gallbladder and their clinicopathological significances

(2012) Guo-shun Shu et al.   PATHOLOGY RESEARCH AND PRACTICE

Identification and Pathway Analysis of microRNAs with No Previous Involvement in Breast Cancer

(2012) Sandra Romero-Cordoba et al.   PLoS One

A comprehensive analysis of precursor microRNA cleavage by human Dicer

(2012) Y. Feng et al.   RNA

Functional parameters of Dicer-independent microRNA biogenesis

(2012) J.-S. Yang et al.   RNA

Alternative RISC assembly: Binding and repression of microRNA-mRNA duplexes by human Ago proteins

(2012) M. M. Janas et al.   RNA

Crosstalk between TGF-β signaling and the microRNA machinery

(2012) Henriett Butz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Modulation of microRNA Activity by Semi-microRNAs

(2012) Isabelle Plante et al.   Frontiers in Genetics

Prognostic Significance of Dicer Cellular Levels in Soft Tissue Sarcomas

(2011) Dionysios J. Papachristou et al.   CANCER INVESTIGATION

miR-125b Is Methylated and Functions as a Tumor Suppressor by Regulating the ETS1 Proto-oncogene in Human Invasive Breast Cancer

(2011) Y. Zhang et al.   CANCER RESEARCH

MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer

(2011) Seong O. Suh et al.   CARCINOGENESIS

A precursor microRNA in a cancer cell nucleus

(2011) Sonia A. Melo et al.   CELL CYCLE

Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome

(2011) Rocio G. Urdinguio et al.   Epigenetics

The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma

(2011) Xiaofang Guo et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

(2011) Taewan Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prognostic values of the miR-17-92 cluster and its paralogs in colon cancer

(2011) Ge Yu et al.   JOURNAL OF SURGICAL ONCOLOGY

Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2

(2011) C. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

EGFR Signals Downregulate Tumor Suppressors miR-143 and miR-145 in Western Diet-Promoted Murine Colon Cancer: Role of G1 Regulators

(2011) H. Zhu et al.   MOLECULAR CANCER RESEARCH

Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

(2011) Suhwan Chang et al.   NATURE MEDICINE

PDGF induced microRNA alterations in cancer cells

(2011) Minghai Shao et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia

(2011) X-N Gao et al.   ONCOGENE

Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

(2011) V Davalos et al.   ONCOGENE

Argonaute proteins regulate microRNA stability: Increased microRNA abundance by Argonaute proteins is due to microRNA stabilization

(2011) Julia Winter et al.   RNA Biology

MicroRNA-451 Is Involved in the Self-renewal, Tumorigenicity, and Chemoresistance of Colorectal Cancer Stem Cells

(2011) Nerea Bitarte et al.   STEM CELLS

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

(2011) Nicolas Léveillé et al.   Nature Communications

MicroRNAs and their isomiRs function cooperatively to target common biological pathways

(2011) Nicole Cloonan et al.   GENOME BIOLOGY

A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells

(2010) Sonia A. Melo et al.   CANCER CELL

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells

(2010) Ronald T.K. Pang et al.   CARCINOGENESIS

Posttranscriptional Regulation of MicroRNA Biogenesis in Animals

(2010) Haruhiko Siomi et al.   MOLECULAR CELL

Smad Proteins Bind a Conserved RNA Sequence to Promote MicroRNA Maturation by Drosha

(2010) Brandi N. Davis et al.   MOLECULAR CELL

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

(2010) Li Ma et al.   NATURE CELL BIOLOGY

CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer

(2010) A Lujambio et al.   ONCOGENE

p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication

(2010) I. G. Cannell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MYCN-regulated microRNAs repress estrogen receptor-  (ESR1) expression and neuronal differentiation in human neuroblastoma

(2010) J. Loven et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia

(2009) X. Agirre et al.   CANCER RESEARCH

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Ars2 Regulates Both miRNA- and siRNA- Dependent Silencing and Suppresses RNA Virus Infection in Drosophila

(2009) Leah R. Sabin et al.   CELL

Ars2 Links the Nuclear Cap-Binding Complex to RNA Interference and Cell Proliferation

(2009) Joshua J. Gruber et al.   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

(2009) Brandi N Davis et al.   Cell Communication and Signaling

Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis

(2009) Tetsuya Ueda et al.   LANCET ONCOLOGY

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

(2009) Michele Trabucchi et al.   NATURE

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

(2009) T.-C. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DICER1 Mutations in Familial Pleuropulmonary Blastoma

(2009) D. A. Hill et al.   SCIENCE

The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators

(2008) Frances V. Fuller-Pace et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

Getting to the Root of miRNA-Mediated Gene Silencing

(2008) Ana Eulalio et al.   CELL

Argonaute-2 Expression Is Regulated by Epidermal Growth Factor Receptor and Mitogen-Activated Protein Kinase Signaling and Correlates with a Transformed Phenotype in Breast Cancer Cells

(2008) Brian D. Adams et al.   ENDOCRINOLOGY

Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype

(2008) Brandi N. Davis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

(2008) T. H. Davis et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-155 Is Regulated by the Transforming Growth Factor  /Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

(2008) W. Kong et al.   MOLECULAR AND CELLULAR BIOLOGY

Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops

(2008) Gracjan Michlewski et al.   MOLECULAR CELL

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Primary microRNA transcripts are processed co-transcriptionally

(2008) Mariangela Morlando et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

(2008) William M. Merritt et al.   NEW ENGLAND JOURNAL OF MEDICINE

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY