The Multiple Functions of TRBP, at the Hub of Cell Responses to Viruses, Stress, and Cancer

TRBP and eIF6 Homologue in Marsupenaeus japonicus Play Crucial Roles in Antiviral Response

(2012) Shuai Wang et al.   PLoS One

Stress-Induced Phosphorylation of PACT Reduces Its Interaction with TRBP and Leads to PKR Activation

(2011) Madhurima Singh et al.   BIOCHEMISTRY

MicroRNAs and the cell cycle

(2011) María José Bueno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Small RNAs in early mammalian development: from gametes to gastrulation

(2011) N. Suh et al.   DEVELOPMENT

The Many Faces of RNAi

(2011) René F. Ketting   DEVELOPMENTAL CELL

Inhibition of RNase L and RNA-dependent Protein Kinase (PKR) by Sunitinib Impairs Antiviral Innate Immunity

(2011) Babal Kant Jha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cellular TAR RNA Binding Protein, TRBP, Promotes HIV-1 Replication Primarily by Inhibiting the Activation of Double-Stranded RNA-Dependent Kinase PKR

(2011) V. R. Sanghvi et al.   JOURNAL OF VIROLOGY

Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase

(2011) J.-F. Gelinas et al.   JOURNAL OF VIROLOGY

Ebolavirus Proteins Suppress the Effects of Small Interfering RNA by Direct Interaction with the Mammalian RNA Interference Pathway

(2011) G. Fabozzi et al.   JOURNAL OF VIROLOGY

siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes

(2011) Cameron L. Noland et al.   MOLECULAR CELL

Reconstitution of human RNA interference in budding yeast

(2011) K. Suk et al.   NUCLEIC ACIDS RESEARCH

A Re-Examination of Global Suppression of RNA Interference by HIV-1

(2011) Viraj R. Sanghvi et al.   PLoS One

The Role of Dicer Protein Partners in the Processing of MicroRNA Precursors

(2011) Edyta Koscianska et al.   PLoS One

Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing

(2011) S. Melo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes

(2011) S. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions

(2011) Ghislaine Laraki et al.   RNA Biology

On the nature of in vivo requirements forrde-4in RNAi and developmental pathways inC. elegans

(2011) Daniel Blanchard et al.   RNA Biology

Virus-encoded microRNAs

(2011) Adam Grundhoff et al.   VIROLOGY

A proteomic study of TAR-RNA binding protein (TRBP)-associated factors

(2011) Ya-Hui Chi et al.   Cell and Bioscience

Biochemical Principles of Small RNA Pathways

(2010) Qinghua Liu et al.   Annual Review of Biochemistry

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors

(2010) Julia J.M. Eekels et al.   ANTIVIRAL RESEARCH

Recognition of siRNA Asymmetry by TAR RNA Binding Protein

(2010) Joseph A. Gredell et al.   BIOCHEMISTRY

Uncovering the PKR pathway’s potential for treatment of tumors

(2010) Zineb Mounir et al.   Future Oncology

The Role of Protein Kinase R in the Interferon Response

(2010) Agnieszka Pindel et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Substrate-Specific Kinetics of Dicer-Catalyzed RNA Processing

(2010) Srinivas Chakravarthy et al.   JOURNAL OF MOLECULAR BIOLOGY

Somatic mutations and losses of expression of microRNA regulation-related genes AGO2 and TNRC6A in gastric and colorectal cancers

(2010) Min S Kim et al.   JOURNAL OF PATHOLOGY

Tracking a century of global expansion and evolution of HIV to drive understanding and to combat disease

(2010) Denis M Tebit et al.   LANCET INFECTIOUS DISEASES

The activity and expression of microRNAs in prostate cancers

(2010) XuPing Fu et al.   Molecular BioSystems

Reassessing the TARBP2 mutation rate in hereditary nonpolyposis colorectal cancer

(2010) Pilar Garre et al.   NATURE GENETICS

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

A role for human Dicer in pre-RISC loading of siRNAs

(2010) Kumi Sakurai et al.   NUCLEIC ACIDS RESEARCH

Hepatitis C Virus Controls Interferon Production through PKR Activation

(2010) Noëlla Arnaud et al.   PLoS One

Structures of the first and second double-stranded RNA-binding domains of human TAR RNA-binding protein

(2010) Seisuke Yamashita et al.   PROTEIN SCIENCE

Multiple levels of PKR inhibition during HIV-1 replication

(2010) Guerline Clerzius et al.   REVIEWS IN MEDICAL VIROLOGY

The NFAR's (Nuclear Factors Associated with dsRNA): Evolutionarily conserved members of the dsRNA binding protein family

(2010) Glen N. Barber   RNA Biology

Characterization of the TRBP domain required for Dicer interaction and function in RNA interference

(2009) Sylvanne M Daniels et al.   BMC MOLECULAR BIOLOGY

Cancer/testis (CT) antigens: Potential targets for immunotherapy

(2009) Otavia L. Caballero et al.   CANCER SCIENCE

Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling

(2009) Zain Paroo et al.   CELL

Hepatitis C Virus Blocks Interferon Effector Function by Inducing Protein Kinase R Phosphorylation

(2009) Urtzi Garaigorta et al.   Cell Host & Microbe

Effect of siRNA terminal mismatches on TRBP and Dicer binding and silencing efficacy

(2009) Hemant K. Kini et al.   FEBS Journal

Binding and Cleavage Specificities of Human Argonaute2

(2009) Walt F. Lima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRBP Homolog Interacts with Eukaryotic Initiation Factor 6 (eIF6) in Fenneropenaeus chinensis

(2009) S. Wang et al.   JOURNAL OF IMMUNOLOGY

The Interferon System and Vaccinia Virus Evasion Mechanisms

(2009) Beatriz Perdiguero et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

ADAR1 Interacts with PKR during Human Immunodeficiency Virus Infection of Lymphocytes and Contributes to Viral Replication

(2009) G. Clerzius et al.   JOURNAL OF VIROLOGY

Hsp90 Regulates the Function of Argonaute 2 and Its Recruitment to Stress Granules and P-Bodies

(2009) Justin M. Pare et al.   MOLECULAR BIOLOGY OF THE CELL

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

Structural insights into RNA processing by the human RISC-loading complex

(2009) Hong-Wei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the Human Dicer-TRBP Complex by Electron Microscopy

(2009) Pick-Wei Lau et al.   STRUCTURE

The evolution of core proteins involved in microRNA biogenesis

(2008) Dennis Murphy et al.   BMC EVOLUTIONARY BIOLOGY

Autoinhibition of Human Dicer by Its Internal Helicase Domain

(2008) Enbo Ma et al.   JOURNAL OF MOLECULAR BIOLOGY

dsRNA Binding Properties of RDE-4 and TRBP Reflect Their Distinct Roles in RNAi

(2008) Greg S. Parker et al.   JOURNAL OF MOLECULAR BIOLOGY

TRBP Control of PACT-Induced Phosphorylation of Protein Kinase R Is Reversed by Stress

(2008) A. Daher et al.   MOLECULAR AND CELLULAR BIOLOGY

A small molecule enhances RNA interference and promotes microRNA processing

(2008) Ge Shan et al.   NATURE BIOTECHNOLOGY

A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs

(2008) Harris S. Soifer et al.   NUCLEIC ACIDS RESEARCH

In vitro reconstitution of the human RISC-loading complex

(2008) I. J. MacRae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Argonaute protein family

(2008) Julia Höck et al.   GENOME BIOLOGY

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY