Gli2 silencing enhances TRAIL-induced apoptosis and reduces tumor growth in human hepatoma cells in vivo

Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells

(2012) Shuijun Zhang et al.   PLoS One

Role of apoptotic and necrotic cell death under physiologic conditions

(2011) Song-Iy Han et al.   BMB Reports

shRNA-mediated silencing of Gli2 gene inhibits proliferation and sensitizes human hepatocellular carcinoma cells towards TRAIL-induced apoptosis

(2011) Dawei Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Therapeutic Potential and Molecular Mechanism of a Novel, Potent, Nonpeptide, Smac Mimetic SM-164 in Combination with TRAIL for Cancer Treatment

(2011) J. Lu et al.   MOLECULAR CANCER THERAPEUTICS

The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP

(2010) Hee Jung Um et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage

(2009) Cheng-Yun Jin et al.   ANTI-CANCER DRUGS

NASH and HCC

(2009) John M. Page et al.   Clinics in Liver Disease

The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation

(2009) Daniela Carlisi et al.   EUROPEAN JOURNAL OF CANCER

KAAD-cyclopamine augmented TRAIL-mediated apoptosis in malignant glioma cells by modulating the intrinsic and extrinsic apoptotic pathway

(2009) Markus David Siegelin et al.   NEUROBIOLOGY OF DISEASE

GLI2 Knockdown Using an Antisense Oligonucleotide Induces Apoptosis and Chemosensitizes Cells to Paclitaxel in Androgen-Independent Prostate Cancer

(2008) S. Narita et al.   CLINICAL CANCER RESEARCH

BH3 Mimetic Obatoclax Enhances TRAIL-Mediated Apoptosis in Human Pancreatic Cancer Cells

(2008) S. Huang et al.   CLINICAL CANCER RESEARCH

Ligand-Based Targeting of Apoptosis in Cancer: The Potential of Recombinant Human Apoptosis Ligand 2/Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (rhApo2L/TRAIL)

(2008) Avi Ashkenazi et al.   JOURNAL OF CLINICAL ONCOLOGY