Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells

SMAC Mimetic (JP1201) Sensitizes Non-Small Cell Lung Cancers to Multiple Chemotherapy Agents in an IAP-Dependent but TNF- -Independent Manner

(2011) R. M. Greer et al.   CANCER RESEARCH

c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma

(2011) Hanning You et al.   HEPATOLOGY

Are there opportunities for chemotherapy in the treatment of hepatocellular cancer?

(2011) Uzma Asghar et al.   JOURNAL OF HEPATOLOGY

Therapeutic Potential and Molecular Mechanism of a Novel, Potent, Nonpeptide, Smac Mimetic SM-164 in Combination with TRAIL for Cancer Treatment

(2011) J. Lu et al.   MOLECULAR CANCER THERAPEUTICS

IAP Regulation of Metastasis

(2010) Swarna Mehrotra et al.   CANCER CELL

Smac Mimetic Increases Chemotherapy Response and Improves Survival in Mice with Pancreatic Cancer

(2010) Sean P. Dineen et al.   CANCER RESEARCH

Smac mimetics increase cancer cell response to chemotherapeutics in a TNF-α-dependent manner

(2010) B L Probst et al.   CELL DEATH AND DIFFERENTIATION

Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation

(2010) Terence Kin Wah Lee et al.   HEPATOLOGY

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

(2010) S Whittaker et al.   ONCOGENE

Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma

(2009) Claudia Augello et al.   BMC CANCER

Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound

(2009) H. H. Cheung et al.   CANCER RESEARCH

Targeting of the Akt-Nuclear Factor- B Signaling Network by [1-(4-Chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a Novel Indole-3-Carbinol Derivative, in a Mouse Model of Hepatocellular Carcinoma

(2009) H. A. Omar et al.   MOLECULAR PHARMACOLOGY

Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance

(2008) M. Fakler et al.   BLOOD

SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP

(2008) J. Lu et al.   CANCER RESEARCH

Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence

(2008) Ying-Hong Shi et al.   HEPATOLOGY

IAPs: What's in a Name?

(2008) Srinivasa M. Srinivasula et al.   MOLECULAR CELL

IAP-targeted therapies for cancer

(2008) E C LaCasse et al.   ONCOGENE

Synergistic antitumor activity of XIAP-shRNA and TRAIL expressed by oncolytic adenoviruses in experimental HCC

(2007) Qiuwei Pan et al.   ACTA ONCOLOGICA