The role of the tissue omega-6/omega-3 fatty acid ratio in regulating tumor angiogenesis

Fat-1 transgenic mice with elevated omega-3 fatty acids are protected from allergic airway responses

(2011) Sueleyman Bilal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Omega-3: A link between global climate change and human health

(2011) Jing X. Kang   BIOTECHNOLOGY ADVANCES

Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF- 

(2011) K. H. Weylandt et al.   CARCINOGENESIS

Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinogenesis

(2011) Mary Chatterjee et al.   MOLECULAR CARCINOGENESIS

A high ratio of dietary n-6/n-3 polyunsaturated fatty acids is associated with increased risk of prostate cancer

(2011) Christina D. Williams et al.   NUTRITION RESEARCH

Endogenously Decreasing Tissue n-6/n-3 Fatty Acid Ratio Reduces Atherosclerotic Lesions in Apolipoprotein E –Deficient Mice by Inhibiting Systemic and Vascular Inflammation

(2010) Jian-Bo Wan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis modelOmega-3 fatty acids prevent liver neoplasia

(2010) J. Griffitts et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion

(2010) Y Wu et al.   BRITISH JOURNAL OF CANCER

Healing fats of the skin: the structural and immunologic roles of the ω-6 and ω-3 fatty acids

(2010) Meagen M. McCusker et al.   CLINICS IN DERMATOLOGY

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat-Fed Mice

(2010) P. J. White et al.   DIABETES

Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/ AP-1 pathway

(2009) Ming-Hsien Chien et al.   CARCINOGENESIS

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

The effect of omega-3 FAs on tumour angiogenesis and their therapeutic potential

(2009) Laura Spencer et al.   EUROPEAN JOURNAL OF CANCER

Inhibition of arachidonic acid metabolism and its implication on cell proliferation and tumour-angiogenesis

(2009) C.A.C. Hyde et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Leukotriene D4 Stimulates the Migration but Not Proliferation of Endothelial Cells Mediated by the Cysteinyl Leukotriene CysLT1 Receptor via the Extracellular Signal-Regulated Kinase Pathway

(2009) Yu-Mei Yuan et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking  -catenin and cyclooxygenase-2

(2009) K. Lim et al.   MOLECULAR CANCER THERAPEUTICS

Attenuation of the Systemic Inflammatory Response and Infectious Complications After Gastrectomy with Preoperative Oral Arginine and ω-3 Fatty Acids Supplemented Immunonutrition

(2009) Yoshiki Okamoto et al.   WORLD JOURNAL OF SURGERY

Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis

(2008) Anke C. Webler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reduction of inflammation and chronic tissue damage by omega-3 fatty acids in fat-1 transgenic mice with pancreatitis

(2008) Karsten H. Weylandt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reduced Colitis-Associated Colon Cancer in Fat-1 (n-3 Fatty Acid Desaturase) Transgenic Mice

(2008) Q. Jia et al.   CANCER RESEARCH

Fish oil fed prior to ethanol administration prevents acute ethanol-induced fatty liver in mice

(2008) Satoshi Wada et al.   JOURNAL OF HEPATOLOGY

Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3β phosphorylation

(2008) Yi Lu et al.   MOLECULAR CANCER THERAPEUTICS

A randomised interventional trial of  -3-polyunsaturated fatty acids on endothelial function and disease activity in systemic lupus erythematosus

(2007) S A Wright et al.   ANNALS OF THE RHEUMATIC DISEASES