Driving transcriptional regulators in melanoma metastasis

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PKCε Promotes Oncogenic Functions of ATF2 in the Nucleus while Blocking Its Apoptotic Function at Mitochondria

(2012) Eric Lau et al.   CELL

Hyaluronan-binding protein 1 (HABP1/p32/gC1qR) induces melanoma cell migration and tumor growth by NF-kappa B dependent MMP-2 activation through integrin αvβ3 interaction

(2011) Mansi Prakash et al.   CELLULAR SIGNALLING

An Antibody-Drug Conjugate Targeting the Endothelin B Receptor for the Treatment of Melanoma

(2011) J. Asundi et al.   CLINICAL CANCER RESEARCH

Searching for the ‘melano-miRs’: miR-214 drives melanoma metastasis

(2011) Menashe Bar-Eli   EMBO JOURNAL

microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C

(2011) Elisa Penna et al.   EMBO JOURNAL

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Integrin-linked kinase regulates melanoma angiogenesis by activating NF-κB/interleukin-6 signaling pathway

(2011) A A Wani et al.   ONCOGENE

Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells

(2011) Y Cheli et al.   ONCOGENE

Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny

(2011) Y Cheli et al.   ONCOGENE

Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways

(2011) Yongmei Feng et al.   Pigment Cell & Melanoma Research

MicroRNA-193b Represses Cell Proliferation and Regulates Cyclin D1 in Melanoma

(2010) Jiamin Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Transcriptional control of the melanoma malignant phenotype

(2010) Vladislava O. Melnikova et al.   CANCER BIOLOGY & THERAPY

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

(2010) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-148 Regulates Mitf in Melanoma Cells

(2010) Benedikta S. Haflidadóttir et al.   PLoS One

CREB Inhibits AP-2α Expression to Regulate the Malignant Phenotype of Melanoma

(2010) Vladislava O. Melnikova et al.   PLoS One

Protease activated receptor-1 inhibits the Maspin tumor-suppressor gene to determine the melanoma metastatic phenotype

(2010) G. J. Villares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for ATF2 in Regulating MITF and Melanoma Development

(2010) Meera Shah et al.   PLoS Genetics

Role of miRNAs in the progression of malignant melanoma

(2009) D W Mueller et al.   BRITISH JOURNAL OF CANCER

Overexpression of Protease-Activated Receptor-1 Contributes to Melanoma Metastasis via Regulation of Connexin 43

(2009) G. J. Villares et al.   CANCER RESEARCH

Blockade of PAR1 Signaling with Cell-Penetrating Pepducins Inhibits Akt Survival Pathways in Breast Cancer Cells and Suppresses Tumor Survival and Metastasis

(2009) E. Yang et al.   CANCER RESEARCH

Regulation of RUNX3 Tumor Suppressor Gene Expression in Cutaneous Melanoma

(2009) M. Kitago et al.   CLINICAL CANCER RESEARCH

Crosstalk between Protease-activated Receptor 1 and Platelet-activating Factor Receptor Regulates Melanoma Cell Adhesion Molecule (MCAM/MUC18) Expression and Melanoma Metastasis

(2009) Vladislava O. Melnikova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silencing cAMP-response Element-binding Protein (CREB) IdentifiesCYR61as a Tumor Suppressor Gene in Melanoma

(2009) Andrey S. Dobroff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melanoma Prognostic Model Using Tissue Microarrays and Genetic Algorithms

(2009) Bonnie E. Gould Rothberg et al.   JOURNAL OF CLINICAL ONCOLOGY

Final Version of 2009 AJCC Melanoma Staging and Classification

(2009) Charles M. Balch et al.   JOURNAL OF CLINICAL ONCOLOGY

miRNA Expression Profiling in Melanocytes and Melanoma Cell Lines Reveals miRNAs Associated with Formation and Progression of Malignant Melanoma

(2009) Daniel W. Mueller et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

NF-κB Inhibition through Proteasome Inhibition or IKKβ Blockade Increases the Susceptibility of Melanoma Cells to Cytostatic Treatment through Distinct Pathways

(2009) Katharina Amschler et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study

(2009) Richard C Becker et al.   LANCET

A Gene Expression Signature of Invasive Potential in Metastatic Melanoma Cells

(2009) Aaron R. Jeffs et al.   PLoS One

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

(2009) Miguel F. Segura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activated Wnt/ss-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

(2009) A. J. Chien et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Melanoma Growth and Metastasis with Systemic Delivery of Liposome-Incorporated Protease-Activated Receptor-1 Small Interfering RNA

(2008) Gabriel J. Villares et al.   CANCER RESEARCH

MicroRNA-137 Targets Microphthalmia-Associated Transcription Factor in Melanoma Cell Lines

(2008) L. T. Bemis et al.   CANCER RESEARCH

The Promyelocytic Leukemia Zinc Finger-MicroRNA-221/-222 Pathway Controls Melanoma Progression through Multiple Oncogenic Mechanisms

(2008) F. Felicetti et al.   CANCER RESEARCH

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

(2008) Julia Schultz et al.   CELL RESEARCH

Frequencies of NRAS and BRAF Mutations Increase from the Radial to the Vertical Growth Phase in Cutaneous Melanoma

(2008) Victoria R. Greene et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Integrin β3 expression is regulated by let-7a miRNA in malignant melanoma

(2008) D W Müller et al.   ONCOGENE

Melanoma and the tumor microenvironment

(2008) Jessie Villanueva et al.   Current Oncology Reports