Eicosanoids and other lipid mediators and the tumor hypoxic microenvironment

Identification of the Orphan G Protein-coupled Receptor GPR31 as a Receptor for 12-(S)-Hydroxyeicosatetraenoic Acid

(2011) Yande Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclooxygenase-2 and Cancer Treatment: Understanding the Risk Should Be Worth the Reward

(2010) D. G. Menter et al.   CLINICAL CANCER RESEARCH

12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells

(2010) Sriram Krishnamoorthy et al.   EXPERIMENTAL CELL RESEARCH

Hypoxia-Mediated Expression of 5-Lipoxygenase-Activating Protein Involves HIF-1  and NF- B and MicroRNAs 135a and 199a-5p

(2010) C. S. Gonsalves et al.   JOURNAL OF IMMUNOLOGY

EP1 Prostanoid Receptor Coupling to Gi/o Up-Regulates the Expression of Hypoxia-Inducible Factor-1  through Activation of a Phosphoinositide-3 Kinase Signaling Pathway

(2010) R. Ji et al.   MOLECULAR PHARMACOLOGY

An update on sphingosine-1-phosphate and other sphingolipid mediators

(2010) Henrik Fyrst et al.   Nature Chemical Biology

Sphingosine-1-Phosphate

(2009) Maude D. Michaud et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

When the Sphingosine Kinase 1/Sphingosine 1-Phosphate Pathway Meets Hypoxia Signaling: New Targets for Cancer Therapy

(2009) I. Ader et al.   CANCER RESEARCH

Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis

(2009) James J. Lee et al.   CARCINOGENESIS

HGF/Met signalling promotes PGE2 biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells

(2009) A. E. Moore et al.   CARCINOGENESIS

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

The expression level of sphingosine-1-phosphate receptor type 1 is related to MIB-1 labeling index and predicts survival of glioblastoma patients

(2009) Yuya Yoshida et al.   JOURNAL OF NEURO-ONCOLOGY

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Repression of 15-Hydroxyprostaglandin Dehydrogenase Involves Histone Deacetylase 2 and Snail in Colorectal Cancer

(2008) M. G. Backlund et al.   CANCER RESEARCH

Sphingosine Kinase 1: A New Modulator of Hypoxia Inducible Factor 1  during Hypoxia in Human Cancer Cells

(2008) I. Ader et al.   CANCER RESEARCH