Fluoxetine inhibits monocrotaline-induced pulmonary arterial remodeling involved in inhibition of RhoA–Rho kinase and Akt signalling pathways in rats

Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats

(2011) Xue-qin Li et al.   ACTA PHARMACOLOGICA SINICA

Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats

(2011) Yun Wang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Effects of HIV Protease Inhibitors on Progression of Monocrotaline- and Hypoxia-Induced Pulmonary Hypertension in Rats

(2010) Guillaume Gary-Bobo et al.   CIRCULATION

KMUP-1 inhibits pulmonary artery proliferation by targeting serotonin receptors/transporter and NO synthase, inactivating RhoA and suppressing AKT/ERK phosphorylation

(2010) Hui-Hsuan Chung et al.   VASCULAR PHARMACOLOGY

RhoA and Rho Kinase Activation in Human Pulmonary Hypertension

(2009) Christophe Guilluy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Analysis of Pulmonary Vasodilator Responses to SB-772077-B [4-(7-((3-Amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], a Novel Aminofurazan-Based Rho Kinase Inhibitor

(2009) J. S. Dhaliwal et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone

(2008) Noriyuki Homma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts

(2008) K M Mair et al.   BRITISH JOURNAL OF PHARMACOLOGY

Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension

(2008) M Oka et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dexfenfluramine discontinuous treatment does not worsen hypoxia-induced pulmonary vascular remodeling but activates RhoA/ROCK pathway: Consequences on pulmonary hypertension

(2008) Nicolas Desbuards et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide

(2007) Patrick J. McNamara et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY