Article
Gastroenterology & Hepatology
Sara van Gennep, Sanne W. Evers, Svend T. Rietdijk, Marieke E. Gielen, Nanne K. H. de Boer, Krisztina B. Gecse, Cyriel I. J. Ponsioen, Marjolijn Duijvestein, Geert R. D'Haens, Angela G. E. M. de Boer, Mark Lowenberg
Summary: This study found that almost half of employed individuals with inflammatory bowel disease experience work productivity loss, mainly due to fatigue. Disease activity and disease burden were identified as predictors of work productivity loss.
INFLAMMATORY BOWEL DISEASES
(2021)
Article
Clinical Neurology
RuthAnne Kavelaars, Haley Ward, deMauri S. Mackie, Kushal M. Modi, Anita Mohandas
Summary: This study examined the impact of self-reported and unrecognized anxiety symptoms on costs and quality of life. The research found that individuals with anxiety symptoms experienced worse quality of life, higher direct and indirect costs compared to those without symptoms. The severity of anxiety symptoms further worsened the outcomes.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Developmental
Yanan Zhao, Yanan Luo, Rong Zhang, Xiaoying Zheng
Summary: Autism spectrum disorder has gained international attention due to its prevalence and its impact on families. This study found that families of children with autism spectrum disorder in China bear a significant economic burden, with nonmedical costs and productivity loss being the major components.
Review
Economics
Kimberley Hubens, Marieke Krol, Joanna Coast, Michael F. Drummond, Werner B. F. Brouwer, Carin A. Uyl-de Groot, Leona Hakkaart-van Roijen
Summary: This study aimed to review instruments for measuring productivity loss of paid and unpaid work, and evaluate their suitability for health economic evaluations from a societal perspective. Most identified instruments were not suitable for capturing productivity changes for economic evaluations, highlighting the need for future research to make informed instrument choices.
Article
Gastroenterology & Hepatology
Renata de Sa Brito Froes, Andre da Luz Moreira, Antonio Jose de V. Carneiro, Jessica P. L. Moreira, Ronir R. Luiz, Adriana Maria Hilu de Barros Moreira, Camila Cesar Monnerat, Heitor Siffert Pereira de Souza, Ana Teresa Pugas Carvalho
Summary: In Rio de Janeiro, one-sixth of Crohn's disease patients are affected by work disability, with risk factors mainly related to disease duration and complications. As this disability impacts young patients after a relatively short period of illness, the socioeconomic burden of CD is expected to increase in the future due to the rising prevalence.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Leigh Anne Shafer, Seth Shaffer, Julia Witt, Zoann Nugent, Charles N. Bernstein
Summary: This study aimed to determine the direct and indirect costs of inflammatory bowel disease (IBD) and explore the association between the degree of IBD-related disability and costs. The results showed that higher levels of disability were associated with higher medical and wage loss costs. The study also found that the indirect costs of absenteeism and presenteeism accounted for a significant portion of the total costs among IBD patients.
INFLAMMATORY BOWEL DISEASES
(2022)
Article
Clinical Neurology
Edoardo Caronna, Victor Jose Gallardo, Alicia Alpuente, Marta Torres-Ferrus, Patricia Pozo-Rosich
Summary: Migraine is prevalent among employees in a Spanish tertiary hospital, with 71.2% meeting criteria for migraine. However, awareness and treatment rates are low, resulting in a significant economic loss of 439,848.90 euro/month for the hospital.
JOURNAL OF NEUROLOGY
(2022)
Article
Dermatology
N. Li, A. Teeple, E. Muser, Y. You, M. Song, A. W. Armstrong
Summary: The effects of guselkumab and adalimumab on work productivity loss and associated cost savings in patients with moderate-to-severe psoriasis were compared. Guselkumab was found to be superior to adalimumab in improving work productivity loss and reducing indirect costs.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2022)
Article
Agronomy
Haruna M. Moda, Christopher Nwadike, Mela Danjin, Francis Fatoye, Chidozie E. Mbada, Louise Smail, Pauline J. S. Doka
Summary: This study examined the impact of Quality of Work Life (QoWL) on farm workers in Nigeria, highlighting issues such as long working hours and gender differences. It also emphasized the importance of job satisfaction in enhancing productivity and sustainability in Low- and Middle-Income Countries (LMICs).
Article
Psychology, Multidisciplinary
Serana Chun Yee So, Danielle Wing Lam Ng, Qiuyan Liao, Richard Fielding, Inda Soong, Karen Kar Loen Chan, Conrad Lee, Alice Wan Ying Ng, Wing Kin Sze, Wing Lok Chan, Victor Ho Fun Lee, Wendy Wing Tak Lam
Summary: This study aimed to document the rates and correlates of return to work, work productivity, and activity impairment among Chinese cancer survivors in Hong Kong at one year post-treatment. The results showed that physically demanding jobs and poorer physical functioning delayed return to work, and unmanaged physical symptom and psychological distress hindered work productivity.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Ana Maria Alcalde, Maria Angeles Martinez-Zamora, Meritxell Gracia, Cristina Ros, Mariona Rius, Inmaculada Nicolas, Francisco Carmona
Summary: This study found that patients with adenomyosis have lower scores in health-related quality of life domains, higher levels of anxiety and depression, and increased work productivity loss compared to those without adenomyosis. The presence of adenomyosis is associated with higher yearly estimated indirect costs and significantly impacts women's mental health and daily activities.
JOURNAL OF WOMENS HEALTH
(2021)
Article
Psychology, Developmental
William Spalding, Sepehr Farahbakhshian, Martine C. Maculaitis, Eugenia Y. Peck, Amir Goren
Summary: The study found that in adults with ADHD using oral psychostimulants, lower medication adherence was associated with higher levels of absenteeism and related indirect costs.
JOURNAL OF ATTENTION DISORDERS
(2022)
Article
Rheumatology
Alan Xu, Caitlyn Sun, Robert Metcalf, Vidya Limaye
Summary: The study examined the impact of idiopathic inflammatory myopathies (IIM) on health-related quality of life (HRQOL) and work productivity (WP) in a South Australian cohort. Various assessment tools were used to measure the impacts, and the results showed significantly lower HRQOL outcome scores in most SF-36 domains compared to population norms. There were also significant associations between muscle strength testing scores and HRQOL and WP.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2021)
Article
Dermatology
Manabu Ohyama, Kazumasa Kamei, Akira Yuasa, Peter Anderson, Gary Milligan, Masayo Sakaki-Yumoto
Summary: This study aimed to quantify the personal and nationwide economic burden of alopecia areata (AA) in Japan. The findings from physician and patient questionnaires revealed that AA significantly impacted patients' productivity and daily activities, resulting in substantial economic losses. These data highlight the need for targeted interventions to reduce the effects of AA on the Japanese economy.
JOURNAL OF DERMATOLOGY
(2023)
Article
Green & Sustainable Science & Technology
Walter Stefanoni, Francesco Latterini, Javier Prieto Ruiz, Simone Bergonzoli, Nadia Palmieri, Luigi Pari
Summary: The growing demand for camelina oil in food and non-food industries is driving interest in investment from farmers and contractors. A study conducted in Spain showed that camelina seeds can be harvested using the same combine harvester used for cereal harvesting, with some seed loss. Adjusting the working speed and rotation speed of the combine harvester may help reduce this loss.
Letter
Rheumatology
Maja Skov Kragsnaes, Jens Kjeldsen, Hans Christian Horn, Heidi Lausten Munk, Jens Kristian Pedersen, Soren Andreas Just, Palle Ahlquist, Jesper Romhild Davidsen, Anna Christine Nilsson, Richard Rottger, Mogens Kruhoffer, Julian R. Marchesi, Karsten Kristiansen, Robin Christensen, Torkell Ellingsen
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Editorial Material
Gastroenterology & Hepatology
Casper Steenholdt, John Gade
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Editorial Material
Gastroenterology & Hepatology
Casper Steenholdt, Lene Buhl Riis
FRONTLINE GASTROENTEROLOGY
(2023)
Article
Gastroenterology & Hepatology
Kristin H. Bjorlykke, Jorgen Jahnsen, Jorn Brynskov, Pauliina Molander, Michael Eberhardson, Loa G. Davidsdottir, Taina Sipponen, Henrik Hjortswang, Guro Lovik Goll, Silje Watterdal Syversen, Ebbe Langholz, Kristin K. Jorgensen, Casper Steenholdt
Summary: Therapeutic drug monitoring (TDM) is widely implemented and utilized in Scandinavia to optimize biologic and thiopurine therapies in inflammatory bowel disease (IBD). However, the lack of guidelines and delayed test response time are the main barriers to the use of TDM.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2023)
Editorial Material
Gastroenterology & Hepatology
Emilie K. Dahl, Osama K. Abed, Jens Kjeldsen, Marco Donia, Inge M. Svane, Anders Dige, Jorgen S. Agnholt, Jacob T. Bjerrum, Jakob B. Seidelin
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Casper Steenholdt, Ruben Due Lorentsen, Pernille Norgaard Petersen, Jorn Brynskov
Summary: Improvement in health-related quality of life (QoL) and fatigue is observed in patients with inflammatory bowel disease (IBD) receiving vedolizumab therapy. The improvement in QoL is rapid, while the improvement in fatigue is slow.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Christian Borup, Lars Vinter-Jensen, Soren Peter German Jorgensen, Signe Wildt, Jesper Graff, Tine Gregersen, Anna Zaremba, Trine Borup Andersen, Camilla Nojgaard, Hans Bording Timm, Dominique Rainteau, Svend Hoime Hansen, Juri Johannes Rumessen, Lars Kristian Munck
Summary: This study investigated the efficacy and safety of colesevelam in the treatment of bile acid diarrhoea. The results showed that colesevelam was superior to placebo in inducing remission of bile acid diarrhoea, and it was well-tolerated with no serious adverse events.
LANCET GASTROENTEROLOGY & HEPATOLOGY
(2023)
Letter
Gastroenterology & Hepatology
Emilie Dahl, Osama Abed, Jorgen Agnholt, Jacob Bjerrum, Anders Dige, Jens Kjeldsen, Inge Svane, Marco Donia, Jakob Seidelin
Summary: This article is linked to Dahl et al papers. To view these articles, visit...
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Bente Mertz Norgard, Floor Dijkstra Zegers, Torben Knudsen, Jens Kjeldsen, Ken Lund, Jacob Broder Brodersen, Jan Nielsen
Summary: This study investigated the initiation of medications, drug persistency, and surgeries in elderly patients with inflammatory bowel disease (IBD). The results showed a significantly lower chance of medication initiation in elderly patients, but comparable drug persistency to adult patients. Clinicians should carefully consider the use of IBD-specific medications in elderly patients and timely discontinuation of corticosteroids.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Bente Mertz Norgard, Floor Dijkstra Zegers, Jan Nielsen, Torben Knudsen, Jens Kjeldsen
Summary: This study examined the association between COVID-19 infection and corticosteroid prescriptions in patients with inflammatory bowel diseases (IBD). The results showed that COVID-19 infection did not result in a higher rate of corticosteroid prescriptions, which is reassuring for patients with IBD.
INFLAMMATORY BOWEL DISEASES
(2023)
Review
Gastroenterology & Hepatology
Casper Steenholdt, Pernille Dige Ovesen, Jorn Brynskov, Jakob Benedict Seidelin
Summary: This systematic review analyzed the efficacy, safety, and integration of Tofacitinib in the treatment of acute severe ulcerative colitis (ASUC). The results showed that Tofacitinib has promising results in ASUC with high short-term colectomy-free survival. However, larger and high-quality studies are still needed to further evaluate its effectiveness.
JOURNAL OF CROHNS & COLITIS
(2023)
Article
Gastroenterology & Hepatology
Ken Lund, Floor Dijkstra Zegers, Jan Nielsen, Jacob Broder Brodersen, Torben Knudsen, Jens Kjeldsen, Michael Due Larsen, Bente Mertz Norgard
Summary: This study investigated the effect of inflammatory bowel disease (IBD) onset on the prescription pattern of non-IBD medication and the risk of becoming a new user. The results showed that the prescription of non-IBD medication significantly increased after IBD onset in patients of different age groups. Elderly patients had an increased risk of becoming new users of non-IBD medication.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Nursing
Janni Petersen Fallesen, Marie Louise Krogh, Lisbeth Rosenbek Minet, Mette Maria Skjoth, Torben Knudsen, Jens Kjeldsen
Summary: This study aims to explore the communication experiences between patients with Inflammatory bowel disease and healthcare professionals in outpatient clinics, and to identify the important factors such as easy access, predictability of follow-up appointments, privacy, and quality of time with healthcare professionals.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Medicine, General & Internal
Ruben D. Lorentsen, Lene B. Riis, Casper Steenholdt
Summary: Small bowel villous atrophy is commonly caused by celiac disease in the Western world, but the possibility of other diseases should be explored in patients without positive serology. This article reports a case of autoimmune enteropathy in an 82-year-old woman with autoimmune thyroiditis, presenting with weight loss and non-responsive watery diarrhea. Diagnosis was based on chronic diarrhea, autoimmune predisposition, villous atrophy, typical histological findings, and no evidence of immunodeficiency or medication-induced villous atrophy. The patient responded well to corticosteroids but required total parenteral nutrition during admission. The possibility of autoimmune enteropathy should be considered in cases of villous atrophy without positive celiac serology.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Medicine, Research & Experimental
Ken Lund, Torben Knudsen, Jens Kjeldsen, Rasmus Gaardskaer Nielsen, Carsten Bogh Juhl, Bente Mertz Norgard
Summary: This study aims to investigate the effect of exercise intervention on moderately active IBD patients, evaluating its impact on disease-specific health-related quality of life, general health status, and biomarkers.